Results 11 to 20 of about 102,448 (310)
Are Viral Vectors Any Good for RNAi Antiviral Therapy?
Viruses, 2020 RNA interference (RNAi) represents a novel approach for alternative antiviral therapy. However, issues related to RNA delivery and stability have presented serious obstacles for obtaining good therapeutic efficacy.
Kenneth Lundstrom
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Tree Shrew as an Emerging Small Animal Model for Human Viral Infection: A Recent Overview
Viruses, 2021 Viral infection is a global public health threat causing millions of deaths. A suitable small animal model is essential for viral pathogenesis and host response studies that could be used in antiviral and vaccine development.
Mohammad Enamul Hoque Kayesh +3 more
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Animal Models for Hepatitis E Virus [PDF]
Viruses, 2019 Hepatitis E virus (HEV) is an underdiagnosed pathogen with approximately 20 million infections each year and currently the most common cause of acute viral hepatitis.
Laura Corneillie +2 more
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Viruses, 2023 Hepatitis E virus (HEV) is the major cause of acute viral hepatitis worldwide. This virus is responsible for waterborne outbreaks in low-income countries and zoonosis transmission in industrialized regions.
Oliver Viera-Segura +3 more
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JHEP Reports, 2022 Background & Aims: HBV has a narrow host restriction, with humans and chimpanzees representing the only known natural hosts. The molecular correlates of resistance in species that are commonly used in biomedical research, such as mice, are currently ...
Lei Wei +6 more
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Frontiers in Microbiology, 2023 IntroductionPaslahepevirus balayani (Hepatitis E virus; HEV) is an emerging virus that poses as a public health threat. The virus is now reported to be the leading cause of acute viral hepatitis, with a unique impact on African settings.
Adeolu S. Oluremi +13 more
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Frontiers in Microbiology, 2021 Hepatitis B virus (HBV) infection is a global public health problem that plagues approximately 240 million people. Chronic hepatitis B (CHB) often leads to liver inflammation and aberrant repair which results in diseases ranging from liver fibrosis ...
Xiaonan Zhang +5 more
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New animal models for hepatitis C viral infection and pathogenesis studies [PDF]
World Journal of Gastroenterology, 2007 Hepatitis C virus (HCV) is a major cause of chronic liver disease, cirrhosis and hepatocellular carcinoma (HCC). In man, the pathobiological changes associated with HCV infection have been attributed to both the immune system and direct viral cytopathic effects.
Dina, Kremsdorf, Nicolas, Brezillon
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The Hepatitis E Virus Open Reading Frame 2 Protein: Beyond Viral Capsid
Frontiers in Microbiology, 2021 Hepatitis E virus (HEV) is a zoonotic pathogen causing hepatitis in both human and animal hosts, which is responsible for acute hepatitis E outbreaks worldwide. The 7.2 kb genome of the HEV encodes three well-defined open reading frames (ORFs), where the
Zhaobin Zhou +6 more
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Interferon signaling in viral hepatitis [PDF]
, 2013 Hepatitis C virus (HCV) is a single stranded positive RNA virus classified in 6 different genotypes. Hepatocytes are the main targets of HCV infection. It has been estimated that 60 to 70% of the infected patients develop chronic infection.
Trincucci, Gaia
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