Results 11 to 20 of about 104,518 (264)
Viruses, 2023 Hepatitis E virus (HEV) is the major cause of acute viral hepatitis worldwide. This virus is responsible for waterborne outbreaks in low-income countries and zoonosis transmission in industrialized regions.
Oliver Viera-Segura +3 more
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JHEP Reports, 2022 Background & Aims: HBV has a narrow host restriction, with humans and chimpanzees representing the only known natural hosts. The molecular correlates of resistance in species that are commonly used in biomedical research, such as mice, are currently ...
Lei Wei +6 more
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Are Viral Vectors Any Good for RNAi Antiviral Therapy?
Viruses, 2020 RNA interference (RNAi) represents a novel approach for alternative antiviral therapy. However, issues related to RNA delivery and stability have presented serious obstacles for obtaining good therapeutic efficacy.
Kenneth Lundstrom
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Frontiers in Microbiology, 2023 IntroductionPaslahepevirus balayani (Hepatitis E virus; HEV) is an emerging virus that poses as a public health threat. The virus is now reported to be the leading cause of acute viral hepatitis, with a unique impact on African settings.
Adeolu S. Oluremi +13 more
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Frontiers in Microbiology, 2021 Hepatitis B virus (HBV) infection is a global public health problem that plagues approximately 240 million people. Chronic hepatitis B (CHB) often leads to liver inflammation and aberrant repair which results in diseases ranging from liver fibrosis ...
Xiaonan Zhang +5 more
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New animal models for hepatitis C viral infection and pathogenesis studies [PDF]
World Journal of Gastroenterology, 2007 Hepatitis C virus (HCV) is a major cause of chronic liver disease, cirrhosis and hepatocellular carcinoma (HCC). In man, the pathobiological changes associated with HCV infection have been attributed to both the immune system and direct viral cytopathic effects.
Dina, Kremsdorf, Nicolas, Brezillon
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The Hepatitis E Virus Open Reading Frame 2 Protein: Beyond Viral Capsid
Frontiers in Microbiology, 2021 Hepatitis E virus (HEV) is a zoonotic pathogen causing hepatitis in both human and animal hosts, which is responsible for acute hepatitis E outbreaks worldwide. The 7.2 kb genome of the HEV encodes three well-defined open reading frames (ORFs), where the
Zhaobin Zhou +6 more
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Experimental Viral Hepatitis in the Dog: Production of Persistent Disease in Partially Immune Animals* [PDF]
Journal of Clinical Investigation, 1967 Experimental infection with canine hepatitis virus has been studied in a series of 49 dogs. The pattern of response to infection was distinctly modified by the immune status of the animal. All of 19 fully susceptible dogs had an acute, fulminating fatal hepatitis when infected with a standard dose of virus, and all of 19 dogs with high levels of ...
D J, Gocke +4 more
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Viruses, 2021 In European countries, autochthonous acute hepatitis E cases are caused by Hepatitis E Virus (HEV) genotype 3 and are usually observed as sporadic cases.
Anna Rosa Garbuglia +15 more
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Infectious canine hepatitis: animal model for viral-induced disseminated intravascular coagulation [PDF]
Blood, 1976 The objective of this study was to characterize the hemostatic defect in dogs with infectious canine hepatitis (ICH), a naturally occurring viral disease of dogs. Five littermate dogs were inoculated with 10(3) TCID50 of ICH virus intravenously. Two littermates were controls. The clinicopathologic manifestations of ICH were fever, depression, anorexia,
D H, Wigton, G J, Kociba, E A, Hoover
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