Results 41 to 50 of about 102,448 (310)

Natural reservoirs for homologs of hepatitis C virus

Emerging Microbes and Infections, 2014
Hepatitis C virus is considered a major public health problem, infecting 2%–3% of the human population. Hepatitis C virus infection causes acute and chronic liver disease, including chronic hepatitis, cirrhosis and hepatocellular carcinoma.
Stephanie Pfaender, Richard JP Brown, Thomas Pietschmann, Eike Steinmann   +3 more
doaj   +1 more source

Estimation of hepatitis E virus transmission among pigs due to contact-exposure

, 2008
Locally acquired hepatitis E in humans from industrialized countries has been repeatedly suggested to originate from pigs. Pigs may serve as a reservoir of hepatitis E virus (HEV) for humans when a typical infected pig causes on average more than one ...
Saskia A. Rutjes, Wellenberg, Gerard, van der Poel, W.H.M., Rutjes, Saskia, de Jong, Mart, Frankena, K., de Jong, M.C.M., Rutjes, S.A., van Der Poel, Wim, Poel, W.H.M., van der, Martijn Bouwknegt, Frankena, Klaas, Roda Husman, A.M., de, Mart C.M. de Jong, Gerard J. Wellenberg, Bouwknegt, M., Jong, M.C.M., de, Klaas Frankena, Wellenberg, G.J., de Roda Husman, A.M., Ana Maria de Roda Husman, Bouwknegt, Martijn, Wim H.M. van der Poel, de Roda Husman, Ana Maria   +23 more
core   +1 more source

Virus demyelination [PDF]

, 2003
A number of viruses can initiate central nervous system (CNS) diseases that include demyelination as a major feature of neuropathology. In humans, the most prominent demyelinating diseases are progressive multifocal leukoencephalopathy, caused by JC ...
Fazakerley, John K, Walker, Robert
core   +1 more source

(−)-Lariciresinol Isolated from the Roots of Isatis indigotica Fortune ex Lindl. Inhibits Hepatitis B Virus by Regulating Viral Transcription

Molecules, 2022
Chronic hepatitis induced by hepatitis B virus (HBV) infection is a serious public health problem, leading to hepatic cirrhosis and liver cancer. Although the currently approved medications can reliably decrease the virus load and prevent the development
Lu Yang, Huiqiang Wang, Haiyan Yan, Kun Wang, Shuo Wu, Yuhuan Li   +5 more
doaj   +1 more source

A twist in the tail : SHAPE mapping of long-range interactions and structural rearrangements of RNA elements involved in HCV replication [PDF]

, 2011
The RNA structure and long-range interactions of the SL9266 cis-acting replication element located within the NS5B coding region of hepatitis C virus (HCV) were determined using selective 2′-hydroxyl acylation analysed by primer extension.
Tuplin, Andrew, Struthers, Madeleine, Struthers, M., Andrew Tuplin, Tuplin, A., Struthers, M, Madeleine Struthers, Simmonds, Peter, David J. Evans, Tuplin, A, Evans, DJ, Peter Simmonds, Evans, David J., Simmonds, P., Evans, D. J., Simmonds, P   +15 more
core   +1 more source

Hepatitis C Viral Replication Complex

, 2021
The life cycle of the hepatitis C virus (HCV) can be divided into several stages, including viral entry, protein translation, RNA replication, viral assembly, and release.
Chee-Hing Yang, Hui-Chun Li, Shih-Yen Lo
core   +1 more source

Identification, using sera from exposed animals, of putative viral antigens in livers of primates with callitrichid hepatitis [PDF]

Journal of Virology, 1990
Callitrichid hepatitis (CH) is an acute, frequently fatal viral hepatitis which affects members of the primate family Callitrichidae (R. J. Montali, E. C. Ramsay, C. B. Stephensen, M. Worley, J. A. Davis, and K. V. Holmes, J. Infect. Dis. 160:759-765, 1989; E. C. Ramsay, R. J. Montali, M. Worley, C. B. Stephensen, and K. V. Holmes, J. Zoo Wildlife Med.
C B, Stephensen, R J, Montali, E C, Ramsay, K V, Holmes   +3 more
openaire   +2 more sources

Serologic study of pig-associated viral zoonoses in Laos

, 2012
We conducted a serologic survey of four high-priority pig-associated viral zoonoses, Japanese encephalitis virus (JEV), hepatitis E virus (HEV), Nipah virus (NiV), and swine influenza virus (SIV), in Laos. We collected blood from pigs at slaughter during
Jarman, R.G., Thompson, R.C.A., Lunt, R. A., Blacksell, SD, Blacksell, S.D., Conlan, J.V., Vongxay, K., Lunt, RA, Gibbons, RV, Gibbons, R.V., Thompson, RC, Fenwick, S., Vongxay, K, Jarman, RG, Conlan, JV, Fenwick, S   +15 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Closed circular viral DNA and asymmetrical heterogeneous forms in livers from animals infected with ground squirrel hepatitis virus [PDF]

Journal of Virology, 1983
To identify possible intermediates in the replication of ground squirrel hepatitis virus, we characterized the major forms of intracellular virus-specific DNA in the livers of infected ground squirrels. A variety of DNA species were found: covalently closed circular molecules, relaxed circular molecules, and a heterogeneous collection of molecules that
B, Weiser, D, Ganem, C, Seeger, H E, Varmus   +3 more
openaire   +2 more sources