Results 11 to 20 of about 94,580 (185)
ZO-2 determines cell membrane localization of receptor NTCP and supports hepatitis B virus infection [PDF]
mBioHepatitis B virus (HBV) infects hepatocytes by using sodium taurocholate cotransporting polypeptide (NTCP) as a receptor. NTCP can render non-permissive hepatocyte cell lines such as HepG2 permissive to HBV infection.
Hironori Nishitsuji +8 more
doaj +2 more sources
Viruses, 2021 Laboratory cultivation of viruses is critical for determining requirements for viral replication, developing detection methods, identifying drug targets, and developing antivirals.
Victoria R. Tenge +8 more
doaj +1 more source
The Egyptian Journal of Bronchology, 2022 Coronavirus disease (COVID-19) is caused by the pathogenic virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Egypt has launched a national treatment program to provide a cure for Egyptian patients infected with hepatitis C virus (HCV ...
Essamedin M. Negm
doaj +1 more source
Inhibition of Viral Membrane Fusion by Peptides and Approaches to Peptide Design
Pathogens, 2021 Fusion of lipid-enveloped viruses with the cellular plasma membrane or the endosome membrane is mediated by viral envelope proteins that undergo large conformational changes following binding to receptors.
Nejat Düzgüneş +2 more
doaj +1 more source
Hepatitis A virus cellular receptor 2 (
American Journal of Reproductive Immunology, 2017 ProblemIntrauterine infection caused by viral infection has been implicated to contribute to preterm birth. Hepatitis A virus cellular receptor 2 (HAVCR2) regulates inflammation in non‐gestational tissues in response to viral infection.Method of studyThe aims of this study were to determine the effect of: (i) viral dsRNA analogue polyinosinic ...
Stella Liong +3 more
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Effects of General Anesthesia on 2 Urinary Biomarkers of Kidney Injury—Hepatitis A Virus Cellular Receptor 1 and Lipocalin 2—in Male C57BL/6J Mice [PDF]
Journal of the American Association for Laboratory Animal Science, 2019 Urinary biomarkers are used increasingly for sensitive prediction of kidney injury in preclinical and clinical studies. Given the frequent requirement of anesthesia in various animal models of disease, it is important to define the effects of anesthesia on kidney injury biomarkers to guide the appropriate selection of anesthetic agents and to avoid ...
Krista M, Gibbs +4 more
openaire +2 more sources
Frontiers in Genetics, 2022 T-cell immunoglobulin mucin 3 (TIM-3) has emerged as a promising immune checkpoint target in cancer therapy. However, the profile of the hepatitis A virus cellular receptor 2 (HAVCR2) gene, encoding TIM-3 expression, is still obscure, along with its role
Hetong Li +4 more
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Frontiers in Immunology, 2021 A coronavirus SARS-CoV-2, which has caused the pandemic viral pneumonia disease COVID-19, significantly threatens global public health, highlighting the need to develop effective and safe vaccines against its infection.
Hyein Jeong +3 more
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Inhibitory activity of limonoids from Khaya grandifoliola C.DC (Meliaceae) against hepatitis C virus infection in vitro [PDF]
Avicenna Journal of Phytomedicine, 2021 Objective: A fraction from Khaya grandifoliola has recently been shown to inhibit hepatitis C virus (HCV) infection and three limonoids (17-epi-methyl-6-hydroxylangolensate, 7-deacetoxy-7-oxogedunin and 7-deacetoxy-7R-hydroxygedunin) were purified from ...
Kouam Arnaud +6 more
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OncoImmunology, 2021 Accumulating evidence indicates that immune checkpoint inhibitors (ICIs) can restore CD8+ cytotoxic T lymphocyte (CTL) functions in preclinical models of acute myeloid leukemia (AML).
Jana Rakova +14 more
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