Tin oxide nanowires suppress herpes simplex virus-1 entry and cell-to-cell membrane fusion.
PLoS ONE, 2012 The advent of nanotechnology has ushered in the use of modified nanoparticles as potential antiviral agents against diseases such as herpes simplex virus 1 and 2 (HSV-1) (HSV-2), human immunodeficiency virus (HIV), monkeypox virus, and hepatitis B virus.
James Trigilio +5 more
doaj +1 more source
Molecular Markers of Tubulointerstitial Fibrosis and Tubular Cell Damage in Patients with Chronic Kidney Disease. [PDF]
PLoS ONE, 2015 In chronic kidney disease (CKD), progressive nephron loss causes glomerular sclerosis, as well as tubulointerstitial fibrosis and progressive tubular injury.
Shunsaku Nakagawa +13 more
doaj +1 more source
Frontiers in Pharmacology, 2023 Background: Glycosyltransferase participates in glycosylation modification, and glycosyltransferase alterations are involved in carcinogenesis, progression, and immune evasion, leading to poor outcomes.
Chunyu Zhang, Wei Zhou
doaj +1 more source
Differential expression of hepatitis A virus cellular receptor 2 in human epithelial ovarian cancer.
, 2021 Epithelial ovarian cancer (EOC) is the most lethal gynecologic cancer (1). We performed discovery of genes associated with epithelial ovarian cancer and of the high-grade serous ovarian cancer (HGSC) subtype, using published microarray data (2, 3) to compare global gene expression profiles of normal ovary or fallopian tube with that of primary tumors ...
openaire +2 more sources
Lipid metabolism and HCV infection [PDF]
, 2010 Chronic infection by hepatitis C virus (HCV) can lead to severe liver disease and is a global healthcare problem. The liver is highly metabolically active and one of its key functions is to control the balance of lipid throughout the body.
Boulant, Steeve +7 more
core +1 more source
The hepatitis B virus X protein activates nuclear factor of activated T cells (NF-AT) by a cyclosporin A-sensitive pathway. [PDF]
, 1998 The X gene product of the human hepatitis B virus (HBx) is a transcriptional activator of various viral and cellular genes. We recently have determined that the production of tumor necrosis factor-alpha (TNF-alpha) by HBV-infected hepatocytes is ...
Armesilla, Angel +11 more
core +1 more source
Hepatitis C : host-virus interactions and their impact on treatment response [PDF]
, 2012 Hepatitis C is a major cause of chronic liver disease with over 120 million infected people worldwide. Untreated chronic hepatitis C (CHC) infection leads in 20-50% to liver cirrhosis culminating in cirrhosis-related complications and hepatocellular ...
Dill, Michael Thomas
core +1 more source
Optineurin negatively regulates the induction of IFNβ in response to RNA virus infection [PDF]
, 2010 The innate immune response provides a critical defense against microbial infections, including viruses. These are recognised by pattern recognition receptors including Toll-like receptors (TLRs) and RIG-I like helicases (RLHs).
Harris, M. +42 more
core +1 more source
Interferon signaling in viral hepatitis [PDF]
, 2013 Hepatitis C virus (HCV) is a single stranded positive RNA virus classified in 6 different genotypes. Hepatocytes are the main targets of HCV infection. It has been estimated that 60 to 70% of the infected patients develop chronic infection.
Trincucci, Gaia
core +1 more source
Human immunodeficiency virus : 25 years of diagnostic and therapeutic strategies and their impact on hepatitis B and C virus [PDF]
, 2009 The human immunodeficiency virus (HIV) had spread unrecognized in the human population as sexually transmitted disease and was finally identified by its disease AIDS in 1981.
Hans Wilhelm Doerr +5 more
core +1 more source