Results 141 to 150 of about 133,468 (309)

Making Advanced Therapies Affordable and Accessible: Two Strategic Approaches

open access: yesDeveloping World Bioethics, EarlyView.
ABSTRACT This article explores two complementary strategies for addressing the affordability and access challenges facing advanced therapies. As high development costs and limited market access have led to the withdrawal of several therapies, the article examines how these barriers create ‘valleys of death’ that prevent innovation from reaching ...
Ubaka Ogbogu, Lauren Albrecht
wiley   +1 more source

Hepatitis B Vaccine: Four Decades on

open access: yesVaccines
Hepatitis B virus is a substantial contributor to cirrhosis and hepatocellular carcinoma (HCC) globally. Vaccination is the most effective method for prevention of hepatitis B and its associated morbidity and mortality, and the only method to prevent ...
Maria Mironova, Marc G. Ghany
doaj   +1 more source

The Effectiveness of California Assembly Bill 2109: Personal Belief Exemptions for Kindergarten Immunizations [PDF]

open access: yes, 2016
The numbers of vaccine preventable diseases (VPDs) in the United States has declined with the development, administration, and effectiveness of vaccines during the 1970s and 1980s.
Goishi-Bessey, Lilli Shizuka
core   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino   +10 more
wiley   +1 more source

Polio Eradication: How the War on Terror Has Led to the Persistence of Polio in Afghanistan, Pakistan, and Nigeria [PDF]

open access: yes, 2013
In 1988, the World Health Organization (WHO) initiated a campaign to eradicate the polio virus from the world population (Bari 2006). Since 1988, the WHO has used polio vaccines to successfully interrupt transmission of the disease to new individuals in ...
Rouhana, John Michel
core   +1 more source

Factors Affecting Immune Reconstitution Post‐Allogeneic HSCT in Children: The Case for an Individualized Approach to Vaccination

open access: yesEuropean Journal of Haematology, EarlyView.
ABSTRACT Allogeneic hematopoietic stem cell transplantation (HSCT) is increasingly used to treat malignant and non‐malignant diseases. Following allogeneic HSCT, patients are particularly vulnerable to vaccine‐preventable diseases (VPD) because conditioning depletes immune cells, including memory cells.
Hélène Buvelot   +3 more
wiley   +1 more source

Prescription for the People: An Activist\u27s Guide to Making Medicine Affordable for All [PDF]

open access: yes, 2017
[Excerpt] Because every cure starts with an accurate diagnosis, in this book I explain how and why the current medicines system is dysfunctional and corrupt.
Quigley, Fran
core   +1 more source

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