Results 61 to 70 of about 481,968 (300)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

GB Virus C Infection: Clinical Significance

Canadian Journal of Gastroenterology, 1999
GB virus C (GBV-C) RNA positivity rates were examined in serum specimens from 231 patients with liver disease (23 patients with hepatitis B, 175 patients with hepatitis C, five patients with hepatitis B virus plus hepatitis C virus coinfection, and 28 ...
Xiang Wei Meng, Masafumi Komatsu, Shigetoshi Ohshima, Kunio Nakane, Tomoo Fujii, Takashi Goto, Kazuo Yoneyama, Tomoyuki Kuramitsu, Motokazu Mukaide   +8 more
doaj   +1 more source

METABOLIC AND CARDIOVASCULAR COMORBIDITIES IN BULGARIAN PATIENTS WITH CHRONIC VIRAL B AND C HEPATITIS [PDF]

Journal of IMAB
Recent epidemiologic data on chronic viral B and C hepatitis in Bulgaria are limited.The evolution of these infections depends on liver complications and the presence of nonliver comorbidities.
Radoslava Tsrancheva, Dimitar Stoyanov, Maria Stancheva, Rozita Karakasheva, Blagovest Stoimenov, Ralitsa Pancheva, Svilen Donev, Ventseslav Yordanov, Nikola Stanchev, Ventsislava Pencheva, Diana Stefanova-Petrova   +10 more
doaj   +1 more source

Treatment of anicteric acute hepatitis C with peginterferon alpha-2a plus ribavirin [PDF]

Vojnosanitetski Pregled, 2005
Background. Hepatitis C virus (HCV) infection is the most frequent cause of chronic hepatitis, cirrhosis, and hepatocellular carcinoma in the world. Acute hepatitis C is the most commonly asymptomatic liver disease with the development of chronic HCV ...
Delić Dragan, Nešić Zorica I., Prostran Milica Š., Simonović Jasmina, Švirtlih Neda   +4 more
doaj   +1 more source

Antioxidant status and glutathione metabolism in peripheral blood mononuclear cells from patients with chronic hepatitis C [PDF]

, 1999
BACKGROUND/AIMS: Oxidative stress could play a role in the pathogenesis of hepatitis C virus infection. We investigated the oxidant/antioxidant status in peripheral blood mononuclear cells from patients with chronic hepatitis C and controls.
Beloqui, O. (Óscar), Boya, P. (Patricia), Castelruiz, Y. (Yurdana), Civeira, M.P. (María Pilar), Conchillo, M. (M.), Larrea, E. (Esther), Peña, A. (Andrés) de la, Prieto, J. (Jesús)   +7 more
core   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Antimitochondrial antibody -M2 positive autoimmune hepatitis during standard of care for chronic hepatitis C. [PDF]

, 2012
The current standard of care (SoC) for chronic hepatitis C, i.e. the combination of a pegylated-interferon (PEG-IFN) with ribavirin (RBV), may activate underlying autoimmune conditions.
ALESSI, Nicola, CABIBI, Daniela, MACALUSO, Fabio Salvatore   +2 more
core   +1 more source

Clinical Outcomes of Patients Within the Rheumatoid Arthritis Care Pathway Cohort at a Tertiary Care Integrated Delivery Network: A Comparison to Usual Care

Arthritis Care &Research, EarlyView.
Objective We aimed to compare clinical outcomes between patients in the Allegheny Health Network rheumatoid arthritis (RA) care pathway and patients receiving usual care. Methods The care pathway initiative implements guideline‐based best practice alongside multidisciplinary team‐based care.
Tarun Sharma, Tyson S. Barrett, Teigan Dwyer, Nancy Campbell, Jessica Heintzinger, Ellen Kraemer, Adam Dore, Susan Manzi   +7 more
wiley   +1 more source

Relation of IL28B gene polymorphism with biochemical and histological features in hepatitis C virus-induced liver disease. [PDF]

PLoS ONE, 2012
BACKGROUND/AIMS:Polymorphism at the IL28B gene may modify the course of hepatitis C virus (HCV) chronic infection. Our aim was to study the influence of IL28B rs12979860 gene polymorphism on the biochemistry and pathology of HCV-induced disease in the ...
José A Agúndez, Elena García-Martin, María L Maestro, Francisca Cuenca, Carmen Martínez, Luis Ortega, Miguel Carballo, Marta Vidaurreta, Marta Agreda, Gabriela Díaz-Zelaya, Avelina Suárez, Manuel Díaz-Rubio, José M Ladero   +12 more
doaj   +1 more source

A hepatitis C virus (HCV) fertőzés pathogenesise: a genetikai és az immunológiai tényezők, valamint az oxidativ stress szerepe és a kórokozó virus sajátosságai, különös tekintettel a HCV-okozta betegségekben és a tünetmentes virushordozó állapotban = Pathogenesis of hepatitis C virus (HCV) infection: the role of the genetic and immunological factors, the oxidative stress and the viral features in the HCV-related diseases and in the symptomfree virus carriers [PDF]

, 2009
Genetikai, immunológiai és környezeti tényezők potenciális szerepe krónikus hepatitis C virus (HCV) infekcióban: összehasonlitó vizsgálatok aktiv HCV hepatitises betegekben és tünetmentes "egészséges" virushordozókban. 1.
Berki, Timea, Hunyady, Béla, Kalabay, László, Nagy, Zsuzsanna, Pár, Alajos, Pár, Gabriella   +5 more
core