Hepatitis D Virus Entry Inhibitors Based on Repurposing Intestinal Bile Acid Reabsorption Inhibitors
Viruses, 2021 Identification of Na+/taurocholate co-transporting polypeptide (NTCP) as high-affinity hepatic entry receptor for the Hepatitis B and D viruses (HBV/HDV) opened the field for target-based development of cell-entry inhibitors. However, most of the HBV/HDV
Michael Kirstgen +7 more
doaj +1 more source
Prevalence of hepatitis D virus among HBsAg-positive individuals,2015-2016: Azar cohort study [PDF]
Health Promotion Perspectives, 2020 Background: Hepatitis D virus (HDV) is a defective RNA pathogen that requires the presence of the hepatitis B virus (HBV) for infection. Middle East countries are endemic areas for HDV infection.
Ali Asghar Pouri +5 more
doaj +1 more source
Blocking entry of hepatitis B and D viruses to hepatocytes as a novel immunotherapy for treating chronic infections [PDF]
, 2021 Background. Chronic hepatitis B and D virus (HBV/HDV) infections can cause cancer. Current HBV therapy using nucleoside analogues (NAs) is life-long and reduces but does not eliminate the risk of cancer.
Ahlén, G +13 more
core +1 more source
BIBLIOMETRIC ANALYSIS OF PUBLICATIONS ON HEPATITIS D VIRUS PUBLISHED IN 1984–2022
Central Asian Journal of Medical Hypotheses and Ethics, 2023 Background: Hepatitis D virus research has advanced in recent decades. In this study, we aim to quantitatively analyze the scientific data in the field of "hepatitis D virus" by using bibliometric analysis. Methods: Research documents published in the
Mehmet Çelik +4 more
doaj +1 more source
A genetic validation study reveals a role of vitamin D metabolism in the response to interferon-alfa-based therapy of chronic hepatitis C [PDF]
, 2012 Background: To perform a comprehensive study on the relationship between vitamin D metabolism and the response to interferon-α-based therapy of chronic hepatitis C.
Badenhoop, Klaus +20 more
core +4 more sources
Modeling the Interplay between HDV and HBV in Chronic HDV/HBV Patients
Mathematics, 2022 Hepatitis D virus is an infectious subviral agent that can only propagate in people infected with hepatitis B virus. In this study, we modified and further developed a recent model for early hepatitis D virus and hepatitis B virus kinetics to better ...
Adequate Mhlanga +9 more
doaj +1 more source
Randomized, Controlled Trial of the Long Term Safety, Immunogenicity and Efficacy of RTS,S/AS02(D) Malaria Vaccine in Infants Living in a Malaria-Endemic Region. [PDF]
, 2013 The RTS,S/AS malaria candidate vaccine is being developed with the intent to be delivered, if approved, through the Expanded Programme on Immunization (EPI) of the World Health Organization.
A Olotu +43 more
core +5 more sources
Clinical, epidemiological and virological features of acute hepatitis B in Italy [PDF]
, 2015 Purpose To evaluate the association of hepatitis B virus (HBV) genotypes, basal core promoter (BCP)/precore (PC) and S gene mutations with the clinical-epidemiological characteristics of acute hepatitis B (AHB) in Italy.
Alessandro Remo Zanetti +10 more
core +1 more source
Эпидемиология и вакцинопрофилактика, 2020 Relevance. In 2016, a resolution was adopted at the 69th World Health Assembly, the goal of which is to eliminate parenteral hepatitis in the world by 2030.
S. S. Sleptsova +7 more
doaj +1 more source
The prevalence of viral hepatitis D in the world
Эпидемиология и вакцинопрофилактика, 2022 Relevance According to many researchers, hepatitis D worsens the prognosis of hepatitis B in 80–90% of cases, accelerating fibrosis and leading to liver cirrhosis or hepatocellular carcinoma. Aims. To present a review of data on prevalence of hepatitis D
V. G. Akimkin +5 more
doaj +1 more source