The western region of the Brazilian Amazon Basin has long been shown to be a highly endemic area for hepatitis B and hepatitis D viruses. Data concerning the prevalence of hepatitis C and E viruses in this region are still scarce.
VS de Paula +3 more
doaj +1 more source
The heterogeneous ribonuclear protein C interacts with the hepatitis delta virus small antigen
Background Hepatitis delta virus (HDV) is considered to be a satellite virus of the Hepatitis B virus. The genome consists of a 1679 nt ssRNA molecule in which a single ORF was identified.
Cunha Celso +3 more
doaj +1 more source
Antibody and B cell responses to Plasmodium sporozoites [PDF]
Antibodies are capable of blocking infection of the liver by Plasmodium sporozoites. Accordingly the induction of anti-sporozoite antibodies is a major aim of various vaccine approaches to malaria.
Cockburn, Ian A. +2 more
core +2 more sources
Baboon-to-human liver transplantation [PDF]
Our ability to control both the cellular and humoral components of xenograft rejection in laboratory experiments, together with an organ shortage that has placed limits on clinical transplantation services, prompted us to undertake a liver ...
A Tzakis +43 more
core +1 more source
The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease. [PDF]
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Moghoofei M +4 more
europepmc +2 more sources
Hepatitis Delta Virus among Hepatitis B Virus-Infected Patients in Jordan: Where Do We Stand? [PDF]
Infection by Hepatitis Delta Virus (HDV) which can only replicate in the presence of Hepatitis B Virus (HBV) is a cause of significant morbidity and mortality worldwide. The prevalence of HDV in Jordan is lacking.
doaj +1 more source
Structural basis of the oligomerization of hepatitis delta antigen [PDF]
BACKGROUND: The hepatitis D virus (HDV) is a small satellite virus of hepatitis B virus (HBV). Coinfection with HBV and HDV causes severe liver disease in humans. The small 195 amino-acid form of the hepatitis delta antigen (HDAg) functions as a trans activator of HDV replication.
Zuccola, Harmon J +4 more
openaire +2 more sources
Interaction of Host Cellular Proteins with Components of the Hepatitis Delta Virus
The hepatitis delta virus (HDV) is the smallest known RNA pathogen capable of propagation in the human host and causes substantial global morbidity and mortality.
Valerie Greco-Stewart, Martin Pelchat
doaj +1 more source
Viral expression and molecular profiling in liver tissue versus microdissected hepatocytes in hepatitis B virus - associated hepatocellular carcinoma. [PDF]
Background: The molecular mechanisms whereby hepatitis B virus (HBV) induces hepatocellular carcinoma (HCC) remain elusive. We used genomic and molecular techniques to investigate host-virus interactions by studying multiple areas of the same liver from
Becker S +16 more
core +1 more source
Diversity of HLA Class I and Class II blocks and conserved extended haplotypes in Lacandon Mayans. [PDF]
Here we studied HLA blocks and haplotypes in a group of 218 Lacandon Maya Native American using a high-resolution next generation sequencing (NGS) method.
Aguilar-Vázquez, José Artemio +23 more
core +1 more source

