Results 31 to 40 of about 24,189 (241)
Medicina, 2019 Several researchers have analyzed the alterations of the methionine cycle associated with liver disease to clarify the pathogenesis of human hepatocellular carcinoma (HCC) and improve the preventive and the therapeutic approaches to this tumor. Different
Rosa M. Pascale +3 more
doaj +1 more source
Mechanisms of hepatocarcinogenesis [PDF]
, 2007 Deep insight on Mechanisms of ...
Lemoine, A +5 more
core +1 more source
Targeting PIN1 as a Therapeutic Approach for Hepatocellular Carcinoma
Frontiers in Cell and Developmental Biology, 2020 PIN1 is a peptidyl-prolyl cis/trans isomerase that specifically binds and catalyzes the cis/trans isomerization of the phosphorylated serine or threonine residue preceding a proline (pSer/Thr-Pro) motif of its interacting proteins.
Chi-Wai Cheng, Eric Tse
doaj +1 more source
The Role of Mitochondrial H+-ATP Synthase in Cancer
Frontiers in Oncology, 2018 Cancer cells reprogram energy metabolism by boosting aerobic glycolysis as a main pathway for the provision of metabolic energy and of precursors for anabolic purposes. Accordingly, the relative expression of the catalytic subunit of the mitochondrial H+-
Pau B. Esparza-Moltó, José M. Cuezva
doaj +1 more source
Adventures in Hepatocarcinogenesis [PDF]
Annual Review of Pathology: Mechanisms of Disease, 2007 Neoplasia is a heritably altered, relatively autonomous growth of tissue. Hepatocarcinogenesis, the pathogenesis of neoplasia in liver, as modeled in the rat exhibits three distinct, quantifiable stages: initiation, promotion, and progression. Simple mutations and/or epigenetic alterations may result in the irreversible stage of initiation.
openaire +2 more sources
-Mediated Hepatocarcinogenesis [PDF]
, 2008 In this review, the role of NF-kappaB in the induction of hepatocarcinogenesis by peroxisome proliferators is examined. The administration of peroxisome proliferators for more than a three-day period leads to the activation of NF-kappaB in the livers of ...
Job Tharappel +13 more
core +1 more source
Genetic Landscape of Multistep Hepatocarcinogenesis
, 2022 Hepatocellular carcinoma (HCC) is a major cause of cancer-related death worldwide. Although several targeted therapy agents are available for advanced HCC, their antitumor efficacy remains limited. As the complex genetic landscape of HCC would compromise
Hiroyuki Marusawa +5 more
core +1 more source
Avocado Oil Attenuates Diethylnitrosamine Induced-Hepatic Carcinogenesis [PDF]
Benha Veterinary Medical Journal, 2018 This study aimed to investigate the efficacy of avocado oil against diethylnitrosamine (DEN) – induced hepatocarcinogenesis in rats. Rats were divided into 5 groups. Group (1) was negative control.
S.G Kasseb +3 more
doaj +1 more source
Pathology-MRI Correlation of Hepatocarcinogenesis: Recent Update [PDF]
, 2015 Understanding the important alterations during hepatocarcinogenesis as well as the characteristic magnetic resonance imaging (MRI) and histopathological features will be helpful for managing patients with chronic liver disease and hepatocellular ...
Jihun Kim +3 more
core +1 more source
Hepatology Communications, 2022 Induction of neoangiogenesis is a hallmark feature during disease progression of hepatocellular carcinoma (HCC). Antiangiogenetic compounds represent a mainstay of therapeutic approaches; however, development of chemoresistance is observed in the ...
Darko Castven +16 more
doaj +1 more source