Results 1 to 10 of about 550 (119)

Characterization and ameliorative effects of Chenopodium murale hydroethanolic extract against diethylnitrosamine-induced hepato-renal damage and malfunction

Journal of the Arab Society for Medical Research, 2023
Background/aim Chenopodium genus has broad applications in folk medicine. Chenopodium murale (C. murale) exhibited several pharmacological benefits, including hypotensive, anti-inflammatory, analgesic, antifungal, antibacterial, phytotoxic ...
Howida S. Abou- Seif, Osama M. Ahmed, Samah A. El-Newary, Marwa E. Shabana, Mahitab I. EL-Kassaby, Ghada M. Elqattan, Hussein G. Sawie   +6 more
doaj   +1 more source

Inhibitory Effect of Thai Purple Rice Husk Extract on Chemically Induced Carcinogenesis in Rats

Molecules, 2021
This study investigated the cancer chemopreventive effects of an acidic methanol extract of purple rice husk on chemically induced carcinogenesis in rats. This purple rice husk extract (PRHE) had high polyphenol contents.
Charatda Punvittayagul, Arpamas Chariyakornkul, Paweena Sankam, Rawiwan Wongpoomchai   +3 more
doaj   +1 more source

Influence of ethanolic extract of Allium sativum on TP53 gene and its anticancer potential in N-Nitrosodiethylamine (NDEA)-induced hepatocellular carcinoma in male albino rats [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): Cancer is a group of genetic disorders in which the behavior of the cell is disturbed by mutation and other abnormalities thereby posing as the leading cause of morbidity and mortality globally.
Godwin Offumobi Ogar, Joseph Bamidele Minari, Adebayo Joseph Bello, Janet Chiwetalu, Oluwafunto Eunice Omogunwa, Oluwadamilola Suzan Oshikoya, Micheal Tobiloba Otaru, Chioma Anastacia Anyanele   +7 more
doaj   +1 more source

Protective Role of Vanillic Acid against Diethylnitrosamine- and 1,2-Dimethylhydrazine-Induced Hepatocarcinogenesis in Rats

Molecules, 2021
This study aimed to evaluate the cancer chemopreventive activity of vanillic acid (VA) in diethylnitrosamine- and 1,2-dimethylhydrazine-induced liver and colon carcinogenesis in rats.
Charatda Punvittayagul, Arpamas Chariyakornkul, Kanokwan Jarukamjorn, Rawiwan Wongpoomchai   +3 more
doaj   +1 more source

Chemopreventive Effect of Cratoxylum formosum (Jack) ssp. pruniflorum on Initial Stage Hepatocarcinogenesis in Rats

Molecules, 2021
Cratoxylum formosum ssp. pruniflorum (Kurz) Gogelein (CP) is an indigenous plant found mainly in southeast Asia. Several in vitro studies have confirmed its activity against hepatocellular carcinoma; however, in vivo studies of the effect of CP on liver ...
Piman Pocasap, Natthida Weerapreeyakul, Rawiwan Wongpoomchai   +2 more
doaj   +1 more source

Chemopreventive effects of Costus comosus Linn against diethylnitrosamine-induced hepatocellular carcinoma in rats [PDF]

Journal of HerbMed Pharmacology, 2022
Introduction: Costus comosus is a potential medicinal plant used traditionally to treat various ailments. The present study aimed to evaluate antioxidant status, lipid peroxidation, and the ameliorative effect of its ethanolic leaf extract against ...
Rachumallu Venkateswararao, Balasubramanian Arul, Ramalingam Kothai   +2 more
doaj   +1 more source

Possible protective effects of resveratrol in hepatocellular carcinoma [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): Resveratrol (RSV) is a naturally occurring plant polyphenol with cardioprotective, neuroprotective, immunoregulatory, and anticancer properties and is biologically effective against various diseases.
SEDA Cetinkaya Karabekir, Aydan Özgörgülü   +1 more
doaj   +1 more source

Cancer chemopreventive potential of cooked glutinous purple rice on the early stages of hepatocarcinogenesis in rats

Frontiers in Nutrition, 2022
Cancer prevention using dietary phytochemicals holds great potential, particularly in the alternative treatment of liver cancer. Our previous study found that the methanol extract of cooked purple rice performed various biological functions including ...
Huina Guo, Huina Guo, Charatda Punvittayagul, Arpamas Vachiraarunwong, Warunyoo Phannasorn, Rawiwan Wongpoomchai   +5 more
doaj   +1 more source

A preliminary study on serum liver function indices of Diethylnitrosamine induced hepatocarcinogenesis and chemoprotective potential of Eclipta alba in male Wistar rats [PDF]

Veterinary World, 2014
Aim: To study the effect of E. alba on liver function in experimental hepatocarcinogenesis in Wistar rats. Materials and Methods: The study was designed to identify the protective effect of Eclipta alba in experimental diethylnitrosamine (DEN) induced ...
R. Anoopraj, S. Hemalatha , C. Balachandran   +2 more
doaj   +1 more source

Sorafenib Alleviates Inflammatory Signaling of Tumor Microenvironment in Precancerous Lung Injuries

Pharmaceuticals, 2023
According to population-based studies, lung cancer is the prominent reason for cancer-related mortality worldwide in males and is also rising in females at an alarming rate. Sorafenib (SOR), which is approved for the treatment of hepatocellular carcinoma
Betul Cicek, Ahmet Hacimuftuoglu, Mehmet Kuzucu, Ahmet Cetin, Yesim Yeni, Sidika Genc, Serkan Yildirim, Ismail Bolat, Mecit Kantarci, Mustafa Gul, Serhat Hayme, Dimitris Matthaios, Dimitra P. Vageli, Sotirios G. Doukas, Aristidis Tsatsakis, Ali Taghizadehghalehjoughi   +15 more
doaj   +1 more source