Results 11 to 20 of about 2,632 (156)

Diethylnitrosamine induces lung adenocarcinoma in FVB/N mouse [PDF]

BMC Cancer, 2018
Background Diethylnitrosamine is a well known carcinogen that induces cancers of various organs in mice and rats. Using FVB/N mouse strain, here we show that diethylnitrosamine induces primarily lung adenocarcinomas with modest tumor development in the ...
Zsolt Mervai, Krisztina Egedi, Ilona Kovalszky, Kornélia Baghy   +3 more
doaj   +2 more sources

Amelioration of diethylnitrosamine (DEN) induced renal oxidative stress and inflammation by Carissa carandas embedded silver nanoparticles in rodents

Toxicology Reports, 2021
Introduction: Inflammation and oxidative stress are the main factors ascribed with interruption in the process of renal tissue impairment. The toxicity of different types of nitrosamine is well recognized in animals and humans.
Deepika Singh, Deepak Chaudhary, Vikas Kumar, Amita Verma   +3 more
doaj   +2 more sources

Possible Protective Anticancer effect of Ethanol Fraction of Iraqi Hibiscus Tiliaceus L. Leaves Extract on Diethylnitrosamine-induced Hepatocarcinogenesis in Male Rats [PDF]

Iraqi Journal of Pharmaceutical Sciences, 2023
Liver cancer with hepatocellular carcinoma a serious clinical illness that progresses quickly and has a bad prognosis because to increased malignancy.
Zahraa Maan Abdul-Azeez, Shihab Hattab Mutlag   +1 more
doaj   +2 more sources

Cancer chemoprevention by an adenosine derivative in a model of cirrhosis-hepatocellular carcinoma induced by diethylnitrosamine in rats

Tumor Biology, 2017
Hepatocellular carcinoma is one of the most common cancers, and approximately 80% develop from cirrhotic livers. We have previously shown that the aspartate salt of adenosine prevents and reverses carbon tetrachloride–induced liver fibrosis in rats ...
Gabriela Velasco-Loyden, Lidia Pérez-Martínez, Susana Vidrio-Gómez, Julio Isael Pérez-Carreón, Victoria Chagoya de Sánchez   +4 more
doaj   +2 more sources

Protective effect of Cassia fistula Linn. on diethylnitrosamine induced hepatocellular damage and oxidative stress in ethanol pretreated rats

Biological Research, 2010
Diethylnitrosamine (DEN), found in many commonly consumed foods, is widely reported to induce cancer in animals and humans. The aim of the present study was to investigate the hepatoprotective and antioxidant activities of the leaf extract of the ...
KANNAMPALLI PRADEEP, CHANDRASEKARAN VICTOR RAJ MOHAN, KUPANNAN GOBIANAND, SIVANESAN KARTHIKEYAN   +3 more
doaj   +1 more source

Morphine does no promote esophageal carcinogenesis in rats exposed to diethylnitrosamine Morfina não promove carcinogênese esofágica em ratos expostos à dietilnitrosamina

Arquivos de Gastroenterologia, 2008
BACKGROUND: The high incidence of esophageal cancer in the north of Iran has been associated to the consumption of opium and exposure to nitrosamines. Diethylnitrosamine has an established potential of producing experimental cancer in the esophagus and ...
Carlos Frota Dillenburg, Cleber Dario Pinto Kruel, Carlos Thadeu Cerski, Maria Isabel Edelweiss, Tiago Luís Dedavid e Silva, André Silvio Schier   +5 more
doaj   +2 more sources

Diethylnitrosamine (DENA) recapitulates formation of hepatic angiosarcoma in pigs.

PLoS ONE, 2019
Background & aimPrimary hepatic angiosarcoma is a rare tumor with poor prognosis. The aim of this study was to generate a new angiosarcoma model to improve research on hepatic angiosarcoma.MethodsPigs sus scrofa were treated with different regimens of ...
Sonja M Kessler, Bettina Leber, Jessica Hoppstädter, Nicole Golob-Schwarzl, Eva M Hofer, Christina S Schultheiss, Hans-Jörg Mischinger, Bernadette Liegl-Atzwanger, Carolin Lackner, Philipp Stiegler, Johannes Haybaeck   +10 more
doaj   +2 more sources

Potential effect of Nigella sativa against Diethylnitrosamine-induced hepatocarcinogenesis in rats [PDF]

, 2017
Objective of the investigation was the study of potential protective effects of the watery extract of Nigella sativa against diethylnitrosamine induced hepatocarcinogenesis in rats. N.
BRELLOU (Γ. ΜΠΡΕΛΛΟΥ), G., LOUKOPOULOS (Π. ΛΟΥΚΟΠΟΥΛΟΣ), P., GAMEEL, A. A., VLEMMAS (Ι. ΒΛΕΜΜΑΣ), I., AHMED, S. E.   +4 more
core   +2 more sources

Enhancing Immunomodulatory Properties of Javanese Turmeric (Curcuma xanthorrhiza) Kombucha against Diethylnitrosamine in Male Balb/c Mice

, 2023
Kombucha is a fermented tea beverage, made by the addition of symbiotic culture of bacteria and yeasts (SCOBY). This study utilized Javanese turmeric in a concentration of 0.4% (w/v) as a kombucha fermentation medium and evaluated its immunomodulatory ...
Ella Saparianti, Ihab Tewfik, Laura Godelive, Hidayat Sujuti, Aldilla Putri Rahayu, Elok Zubaidah, Ignatius Srianta, Eirene Charista Dea, Kiki Fibrianto   +8 more
core   +1 more source

Effect of β-asarone on diethylnitrosamine-induced hepatocellular carcinoma in rats

Indian Journal of Health Sciences and Biomedical Research KLEU, 2016
Aim: This study was designed to evaluate the effect of β-asarone on diethylnitrosamine (DEN) induced and phenobarbital-promoted hepatocellular carcinoma in rats.
Sebashree R Roy, Pramod C Gadad
doaj   +1 more source