Results 31 to 40 of about 12,555 (220)

Biochemical, hematological, peripheral smear and weight evaluation of low dose Epigallocatechin Gallate in Diethylnitrosamine administered rats

open access: yesJournal of Contemporary Medicine, 2023
Background: Currently, with the development of technology, the use of many chemicals especially Diethylnitrosamine (DEN) in agriculture and industry has increased.
Hadi Geylan   +4 more
doaj   +1 more source

A preliminary study on serum liver function indices of Diethylnitrosamine induced hepatocarcinogenesis and chemoprotective potential of Eclipta alba in male Wistar rats [PDF]

open access: yesVeterinary World, 2014
Aim: To study the effect of E. alba on liver function in experimental hepatocarcinogenesis in Wistar rats. Materials and Methods: The study was designed to identify the protective effect of Eclipta alba in experimental diethylnitrosamine (DEN) induced ...
R. Anoopraj   +2 more
doaj   +1 more source

Correlation between Cancer Stem Cells, Inflammation and Malignant Transformation in a DEN-Induced Model of Hepatic Carcinogenesis

open access: yesCurrent Issues in Molecular Biology, 2022
Chronic inflammation and cancer stem cells are known risk factors for tumorigenesis. The aetiology of hepatocellular carcinoma (HCC) involves a multistep pathological process that is characterised by chronic inflammation and hepatocyte damage, but the ...
Chun-Chieh Wu   +7 more
doaj   +1 more source

Combining Transarterial Chemoembolisation With Reduced Deubiquitinase Activity Reduces Hepatocellular Carcinoma Progression. [PDF]

open access: yesJ Cell Mol Med
ABSTRACT To investigate the interplay between ubiquitin‐specific protease 21 (USP21) and programmed death‐ligand 1 (PD‐L1) in the context of Transarterial chemoembolisation (TACE) treatment for hepatocellular carcinoma (HCC) and explore a novel combinatorial strategy to enhance therapeutic efficacy.
Tao Y, Yu W, Yang W, Wu Q, Li J.
europepmc   +2 more sources

Possible protective effects of resveratrol in hepatocellular carcinoma [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2020
Objective(s): Resveratrol (RSV) is a naturally occurring plant polyphenol with cardioprotective, neuroprotective, immunoregulatory, and anticancer properties and is biologically effective against various diseases.
SEDA Cetinkaya Karabekir   +1 more
doaj   +1 more source

Effect of β-asarone on diethylnitrosamine-induced hepatocellular carcinoma in rats

open access: yesIndian Journal of Health Sciences and Biomedical Research KLEU, 2016
Aim: This study was designed to evaluate the effect of β-asarone on diethylnitrosamine (DEN) induced and phenobarbital-promoted hepatocellular carcinoma in rats.
Sebashree R Roy, Pramod C Gadad
doaj   +1 more source

Metformin Improves Biochemical and Pathophysiological Changes in Hepatocellular Carcinoma with Pre-Existed Diabetes Mellitus Rats

open access: yesPathogens, 2021
Hepatocellular carcinoma (HCC) is one of the world’s most widely recognized malignant tumors that accounts for 90% of all the primary liver cancers and is a major cause of death from cancer, representing half a million deaths per year.
Maysa A. Mobasher   +3 more
doaj   +1 more source

A Modified Protocol of Diethylnitrosamine Administration in Mice to Model Hepatocellular Carcinoma

open access: yesInternational Journal of Molecular Sciences, 2020
We aimed to create an animal model for hepatocellular carcinoma (HCC) with a short time, a high survival rate, as well as a high incidence of HCC in both males and females than previously reported.
Azra Memon   +4 more
semanticscholar   +1 more source

Histopathological and clinicopathological studies on the antioxidant effect of gold nanoparticles in diethyInitrosamine induced hepatocarcinogenesis in rats [PDF]

open access: yesVeterinary Medical Journal - Giza, 2016
This study investigated the antioxidant and therapeutic effect of gold nanoparticles (GNPs) against diethylnitrosamine (DENA) induced hepatocarcinogenesis. 24 rats were divided into four groups.
Eman Hassanen   +3 more
doaj   +1 more source

Cancer chemopreventive potential of cooked glutinous purple rice on the early stages of hepatocarcinogenesis in rats

open access: yesFrontiers in Nutrition, 2022
Cancer prevention using dietary phytochemicals holds great potential, particularly in the alternative treatment of liver cancer. Our previous study found that the methanol extract of cooked purple rice performed various biological functions including ...
Huina Guo   +5 more
doaj   +1 more source

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