Newcastle and Doxorubicin attenuated against diethylnitrosoamine as antitumor effects which induced hepatocellular carcinoma [PDF]
Doxorubicin is a broad spectrum antitumor antibiotic. Newcastle disease virus (NDV ) is one such virus with an inherent oncolytic property. This study was done to investigate the antitumor effects of Doxorubicin and NDV on Diethylnitrosamine (DEN ...
mahmoud elashrey +2 more
doaj +1 more source
Newcastle and Doxorubicin attenuated against diethylnitrosoamine as anti-proliferative and immunosuppresor effects which induced hepatocellular carcinoma [PDF]
Doxorubicin is a broad spectrum antitumor antibiotic. Newcastle disease virus (NDV ) is one such virus with an inherent oncolytic property. This study was done to investigate the antitumor effects of Doxorubicin and NDV on Diethylnitrosamine (DEN ...
mahmoud elashrey +2 more
doaj +1 more source
Effect of Carthamus tinctorius L Extract on Diethylnitrosamine-Induced Liver Cirrhosis in Rats [PDF]
Purpose: To explore the effects of Carthamus tinctorius L. extract (CTLE) on diethylnitrosamine (DEN)-induced liver cirrhosis in rats.Methods: CTLE was obtained by extracting the dried Carthamus tinctorius L. in water.
Hu, ZW, Wang, WX
core +1 more source
Disruption of Growth Hormone Receptor Signaling Abrogates Hepatocellular Carcinoma Development
Abedul Haque,1 Vishal Sahu,1 Jamie Lynne Lombardo,2 Lianchun Xiao,3 Bhawana George,1 Robert A Wolff,4 Jeffrey S Morris,3 Asif Rashid,2 John J Kopchick,5,6 Ahmed O Kaseb,4 Hesham M Amin1,7 1Department of Hematopathology, The University of Texas MD ...
Haque A +10 more
doaj
Histopathological and clinicopathological studies on the antioxidant effect of gold nanoparticles in diethyInitrosamine induced hepatocarcinogenesis in rats [PDF]
This study investigated the antioxidant and therapeutic effect of gold nanoparticles (GNPs) against diethylnitrosamine (DENA) induced hepatocarcinogenesis. 24 rats were divided into four groups.
Eman Hassanen +3 more
doaj +1 more source
Investigation of the protective role of a-lipoic acid on rats given diethylnitrosamine [PDF]
Amaç: Çalışmada, dietilnitrozaminin karaciğer üzerindeki toksik etkilerinin belirlenmesi ve bu toksik etkilere bağlı olarak meydana gelebilecek oksidatif strese karşı a-lipoik asidin koruyucu etkisinin araştırılması amaçlanmıştır.
Bayşu Sözbilir, Nalan +1 more
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Ultrastructure of altered hepatocytes induced by diethylnitrosamine (DENA) [PDF]
Administration of diethylnitrosamine I.P. at dose level of 2 mg/kg five days a week to young Sprague-Dawley rats induced foci of altered hepatocytes entirely devoid of glucose-6-phosphatase and adenosine triphosphatase activity. Several weeks later, these foci developed hepatocellular carcinoma mostly of the trabecular type.
openaire +2 more sources
Indigofera linnaei Ali., has been widely used in folk medicine to treat inflammation, liver disorders and swelling of stomach. Earlier studies showed that methanolic extract of Indigofera linnaei (MEIL) possess antioxidant, free radical scavenging ...
Kumar, Sekar Vinoth +4 more
core +1 more source
Avocado Oil Attenuates Diethylnitrosamine Induced-Hepatic Carcinogenesis [PDF]
This study aimed to investigate the efficacy of avocado oil against diethylnitrosamine (DEN) – induced hepatocarcinogenesis in rats. Rats were divided into 5 groups. Group (1) was negative control.
S.G Kasseb +3 more
doaj +1 more source
Apoptosis is characterized by profound morphological changes, but their physiological purpose is unknown. To characterize the role of apoptotic cell contraction, ROCK1 was rendered caspase non-cleavable (ROCK1nc) by mutating aspartate 1113, which ...
Linda Julian +12 more
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