Results 51 to 60 of about 2,632 (156)

Leveraging single‐cell RNA‐seq for uncovering naïve B cells associated with better prognosis of hepatocellular carcinoma

MedComm
Hepatocellular carcinoma (HCC) is a typical highly heterogeneous solid tumor with high morbidity and mortality worldwide, especially in China; however, the immune microenvironment of HCC has not been clarified so far.
Qingjia Sun, Rui Gao, Yingxin Lin, Xianchao Zhou, Tao Wang, Jian He   +5 more
doaj   +1 more source

Anticancer effect of caudatin in diethylnitrosamine‑induced hepatocarcinogenesis in rats

Molecular Medicine Reports, 2020
An overwhelming endoplasmic reticulum stress (ERS) and the following unfolded protein response (UPR) can induce hepatic inflammation, fibrosis and hepatocellular carcinoma (HCC). Caudatin, one of the species of C‑21 steroidal glycosides mainly isolated from the roots of Cynanchum bungei Decne, exhibits potent anticancer activities in vivo. However, the
Song, Jie, Ding, Wenbo, Liu, Bojia, Liu, Dan, Xia, Zhi, Zhang, Li, Cui, Li, Luo, Yi, Jia, Xiaobin, Feng, Liang   +9 more
openaire   +3 more sources

Detection of dimethyl- and diethylnitrosamine in a nigerian fermented milk product (nono) [PDF]

, 1979
The thin layer chromatogram of the dichloromethane extract concentrate of a steam distillate from 20 l of a pooled sample of nono showed 2 distinct violet zones on visualisation with the Preussmann spray reagent.
Maduagwu, E. N., Bassir, Olumbe
core   +1 more source

Effect of Courouptia Guianensis on N-Diethylnitrosamine Induced Oxidative Stress in Wistar Rats. [PDF]

, 2012
The present study shows that the Couroupita guianensis flower extract exhibits excellent hepatoprotective property by restoring the hepatic marker enzymes and by stabilizing and increasing all the components of antioxidant defense system during ...
Kavitha, K V
core  

The beneficial effect of natural antioxidants from olive oil with fig and date palm fruit extracts on biochemical and hematological parameters in rats during diethylnitrosamine-induced carcinogenesis

FACETS, 2018
Diethylnitrosamine (DEN) is a well-known carcinogen. The aim of our study was to determine the role of olive oil (7 g/kg) with fig (1 g/kg) (OF) and (or) date palm (1 g/kg) (D) fruit extracts during DEN treatment of male Wistar rats.
Abdallah H. Fathy, Mohamed A. Bashandy, Samir A. Bashandy, Ahmed M. Mansour   +3 more
doaj   +1 more source

In vivo antitumour potential of camel’s milk against hepatocellular carcinoma in rats and its improvement of cisplatin renal side effects

Pharmaceutical Biology, 2017
Context: Camel milk (CM) is recommended for liver disease patients in Egypt for a strong belief that it has a curative effect. Objective: The effect of consumption of CM with or without chemotherapeutic drug cisplatin was evaluated on induced ...
Hala M. F. El Miniawy, Kawkab A. Ahmed, Sameeh A. Mansour, Marwa M. Salah Khattab   +3 more
doaj   +1 more source

Tumor Promoting Effects of Sulforaphane on Diethylnitrosamine-Induced Murine Hepatocarcinogenesis

, 2022
Nuclear factor erythroid 2-related factor 2 (NRF2) is a key transcription factor involved in protection against initiation of carcinogenesis in normal cells.
Su-Jung Kim, Zheng, Jie, Kim, Seong Hoon, Soma Saeidi, Do-Hee Kim, Young-Joon Surh, Xizhu Fang, Jie Zheng, Kim, Do-Hee, Seong Hoon Kim, Saeidi, Soma, Fang, Xizhu, Kim, Su-Jung, Surh, Young-Joon   +13 more
core   +1 more source

Redefining the hepatoprotective potential of Javanese turmeric (Curcuma xanthorrhiza) Kombucha towards the diethylnitrosamine-induced hepatotoxicity of mice

Purpose This research intended the utilization of Javanese turmeric (0.4% w/v) as a kombucha substrate and analysis of its hepatoprotective activity, in comparison against nonfermented Javanese turmeric beverage (JTB) and black tea kombucha.
Ella Saparianti, Ihab Tewfik, Laura Godelive, Rhytia Ayu Christianty Putri, Hidayat Sujuti, Elok Zubaidah, Ignatius Srianta, Eirene Charista Dea   +7 more
core   +1 more source

Supplementary Methods, Table 1, Figures 1-8 from RETRACTED: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target Genes

, 2010
Supplementary Methods, Table 1, Figures 1-8 from RETRACTED: Loss of Metallothionein Predisposes Mice to Diethylnitrosamine-Induced Hepatocarcinogenesis by Activating NF-κB Target ...
Bo Wang (86769), Wendy Frankel (245634), Satavisha Roy (825237), Kalpana Ghoshal (144593), Sarmila Majumder (144586), Thomas Kaffenberger (10996319), Tsonwin Hai (153515), Samson T. Jacob (14874483), Stefan Costinean (577253), Anna Bratasz (43514), Periannan Kuppusamy (43519)   +10 more
core   +1 more source

Dynamics of Postmortem Gene Expression in Normal and Neoplastic Murine Liver

Life
The use of postmortem (autopsy) material in fundamental and applied biomedical research significantly facilitates the collection of biomaterial for statistically robust sample cohorts.
Evgeny E. Buyko, Ekaterina A. Perina, Danil S. Sobakin, Matvey M. Tsyganov, Dmitry V. Vasilchenko, Sergey V. Vtorushin, Alexander A. Ufandeev, Elena B. Diksas, Olga A. Kaidash, Ekaterina S. Hmelevskaya, Ekaterina V. Parochkina, Igor A. Popov, Vladimir V. Ivanov, Stanislav I. Pekov, Elena V. Udut   +14 more
doaj   +1 more source