Results 71 to 80 of about 2,632 (156)

Role of Lycopersicon esculentum in diethylnitrosamine-induced and phenobarbital-promoted hepatocellular carcinoma

Indian Journal of Health Sciences and Biomedical Research KLEU, 2016
Objective: This study aims to evaluate the role of Lycopersicon esculentum in diethylnitrosamine (DEN)-induced and phenobarbital (PB)-promoted hepatocellular carcinoma.
Bhrigu Kumar Das, Basavaraj C Koti, Pramod C Gadad   +2 more
doaj   +1 more source

Glutathione metabolism in hepatomous liver of rats treated with diethylnitrosamine [PDF]

, 1997
Glutathione metabolism was studied in rat liver during diethylnitrosamine (DEN) carcinogenesis. Some studies were also made in foetal rat liver. Endogenous GSH and non-protein thiols concentrations are increased in DEN-treated rats when compared to non ...
Pinto, Ruy E., Marinho, H.Susana, Baptista, Marco   +2 more
core   +1 more source

Inflammation-Driven Downregulation of CYP2E1 Is Associated with Attenuated Diethylnitrosamine (DEN)-Induced Hepatocarcinogenesis

Cells
Inflammation is widely viewed as a driver of hepatocellular carcinoma (HCC), yet inflammatory signaling also reshapes hepatic xenobiotic metabolism. Here, we established transgenic (Tg) IKKβΔhep mice (Tg-IKKβΔhep), which combine hepatocyte-specific IKKβ ...
Yoshihiro Tsuchiya, Yusuke Sotomaru, Akinori Kanai, Shin Maeda, Hideaki Kamata   +4 more
doaj   +1 more source

Bioactive Potentials of Longan (Dimocarpus longan) Fruit Juice vs Hepatic Carcinoma Initiated by Diethylnitrosamine in Rats [PDF]

مجلة بحوث التربية النوعية
This research aimed to determine the potential role of longan fruit juice in inhibiting the process of hepatic carcinoma in diethylnitrosamine (DEN)-induced rats and enhancing liver recovery. The treatment used two dosages, 100mg/kg/day and 200mg/kg/day,
Nanees Youssef Elmatwally Elsayed Awad, Fatma Wassal Sarhan   +1 more
doaj   +1 more source

Proteomic profiling of expression of proteasomal subunits from livers of mice treated with diethylnitrosamine

, 2013
The liver plays a central role in transforming and clearing chemicals and is susceptible to the toxicity from these agents. Diethylnitrosamine is metabolized primarily in the liver by cytochrome P-450 and can cause DNA damage.
You, Pan, Ma, Qiling, Yuan, Fuqiang, Yang, Zengming, 杨增明, 陶涛, Tao, Tao, Lu, Jia, Yang, Pengyuan   +8 more
core  

Regulation of iron metabolism-related genes in diethylnitrosamine-induced mouse liver tumors

, 2008
Background: It has been suggested that the altered iron metabolism in liver tumors, characterized by the iron-deficient phenotype, is of importance for tumor growth.
Youn, Pilju, Kim, Soohee, Park, Jung-Duck, Ryu, Doug Young, Ahn, Jin Hee, Kim, Yongbaek   +5 more
core   +1 more source

‐diethylnitrosamine‐induced mouse hepatocellular lesions: implications for histogenesis [PDF]

, 2014
Hepatocellular carcinoma (HCC) is a common malignancy with poor clinical outcome, whose histogenesis is the subject of intense debate. Specifically, expression ofcytokeratins (CKs) 7 and 19, associated with aggressive biological behaviour, is proposed to
Ana I. Faustino‐Rocha, Carlos Lopes, Rui M. Gil da Costa, Regina Arantes Rodrigues, Regina Arantes‐Rodrigues, Ana I. Faustino Rocha, Nuno P. Santos, Paula A. Oliveira, Aura Colaço   +8 more
core   +1 more source

Respiratory tract tumours in hamsters exposed to acetaldehyde vapour alone or simultaneously to benzo(a)pyrene or diethylnitrosamine

, 1982
Syrian golden hamsters were exposed to 0 or 2500-1650 ppm acetaldehyde vapour, 7 hr/day, 5 days/week for a period of 52 weeks. A proportion of the animals was given, simultaneously, either intratracheal instillations of benzo(a)pyrene (BP) or ...
Feron, V.J., Kruysse, A., Woutersen, R.A.   +2 more
core  

Diethylnitrosamine and Other N-Nitrosamines in Foods

Journal of AOAC INTERNATIONAL, 1969
Abstract Dimethyl-, diethyl-, di-n-propyl, and other nitrosamines in foods are determined semiquantitatively as follows: (a) initial extraction of the nitrosamines from foods into suitable solvents, (b) isolation of the nitrosamines from other interfering materials by steam distillation and ion exchange cleanup, (c) detection and ...
J J Marleau, L Schwinghamer, Dorothy C Smith, N P Sen   +3 more
openaire   +1 more source

Protein synthesis inhibition induced by dimethylnitrosamine and diethylnitrosamine on isolated rat hepatocytes.

, 1979
Time- and dose-dependent protein synthesis inhibition takes place following exposure to high doses of dimethylnitrosamine (DMN) or diethylnitrosamine (DENA) in isolated rat hepatocytes.
Mattei E, Delpino A, Ferrini U
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