Results 81 to 90 of about 2,632 (156)
Isolated rat hepatocytes were labeled with 35S-methionine in the presence of 25 mM diethylnitrosamine (DENA). The intrinsically labeled proteins were analyzed by one- and two-dimensional gel electrophoresis and the fluorographic patterns were compared ...
Falcioni R +3 more
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Apigenin enhances sorafenib anti-tumour efficacy in hepatocellular carcinoma
Background: The “one drug-one target” paradigm has various limitations affecting drug efficacy, such as resistance profiles and adverse effects. Combinational therapies help reduce unexpected off-target effects and accelerate therapeutic efficacy ...
Deepti Singh +6 more
doaj +1 more source
Lower respiratory tract tumours in Syrian golden hamsters after intratracheal instillations of diethylnitrosamine alone and with ferric oxide [PDF]
A total of 37 tumours of the lower respiratory tract (bronchi, bronchioli and alveoli) was observed in 62 male and female Syrian golden hamsters following 15 weekly intratracheal instillations of diethylnitrosamine (DENA) alone.
Emmelot, P., Feron, V.J., Vossenaar, T.
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The aim of this study was to investigate the effects of a chemical carcinogen, Diethylnitrosamine (DENA), on these markers, sialic acid (SA), lipid-bound sialic acid (LBSA) and the liver enzymes aspartate aminotransferase, alanine aminotransferase, and ...
Sahin, S, Turkmen, G
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Effect of X rays alone or combined with diethylnitrosamine on tumor induction in infant mouse liver.
The possible combined effects of the initiator diethylnitrosamine (DEN) with X rays on cancer induction in C57BL/Cnb mouse liver were evaluated. Four groups of infant mice were treated as follows: with DEN alone, with X rays alone, with DEN + X rays, and
Vankerkom, J +5 more
core +1 more source
Changes in DNA synthesis and cell proliferation during hepatocarcinogenesis by diethylnitrosamine
In the context of a general study on the regulation of proliferation in mammalian cell populations during carcinogenesis, DNA synthesis and proliferative activity in rat liver was investigated during carcinogenesis by continuous administration of ...
Rajewsky, M.
core +1 more source
Role Of The Vitamin C In Diethylnitrosamine-induced Esophageal Cancer In Wistar Rats.
To evaluate the inhibitory effect of vitamin C on the experimental esophageal carcinogenesis induced by diethylnitrosamine (NDEA). Sixty Wistar male rats aged three months, with mean weight of 210 g were employed in the study and were divided into four ...
Lopes, Luiz Roberto +3 more
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Curcumin-containing diet inhibits diethylnitrosamine-induced murine hepatocarcinogenesis
[[abstract]]Curcumin has been widely used as a spice and coloring agent in foods. Recently, curcumin was found to possess chemopreventive effects against skin cancer, forestomach cancer, colon cancer and oral cancer in mice, Clinical trials of curcumin ...
Chuang, SE; Kuo, ML; Hsu, CH; Chen, CR; Lin, JK; Lai, GM; Hsieh, CY; Cheng, AL
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Metformin inhibits early stage of Diethylnitrosamine-induced hepatocarcinogenesis in rats
간세포암종(Hepatocellular carcinoma)은 암 사망률이 높고 아시아에서 가장 잘 발생하는 질환이다. Metformin의 간세포암종 발생에 미치는 조기 억제 효과를 알기 위해, Wistar rat에 16주 동안 주1회 Diethylnitrosamine (DEN) 복강 투여로 사람의 병변과 유사한 성격의 간세포 암종을 유도하였고, Metformin을 음수로 투여하여 간암발생과 재발에 대한 Metformin의 억제효과를 확인하고자 하였다.
조우리
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