Results 91 to 100 of about 2,632 (156)
, 1968 The incorporation of 3H-cytidine (RNA synthesis) into liver explants under standardized in vitro conditions was measured during hepatocarcinogenesis by continuous oral administration of diethylnitrosamine (DENA) to adult rats.
Rajewsky, M.
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Neferine suppresses diethylnitrosamine-induced lung carcinogenesis in Wistar rats
, 2019 [[abstract]]Neferine is a bisbenzylisoquinoline alkaloid isolated from the embryos of lotus which has attracted attention for its anti-inflammatory and anti-cancer activities.
Kalaiselvi, S;Sivalingam, Kalaiselvi;Amirt, Vinoth;Amirthalingam, Vinoth;Karunagaran;Ganasan, Karunagaran;黃志揚;Huang;Chih-Yang;Padma, Vijaya;Viswanadha, Vijaya Padma
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Invasiveness of hyperplastic nodule cells from diethylnitrosamine-treated rat liver
, 1981 Administration of diethylnitrosamine p.o. to female Sprague-Dawley rats induces hepatocellular lesions antecedent to hepatocarcinoma (altered foci and hyperplastic nodules).
De Ridder, Leo Isabelle F J M L. +2 more
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Curcumin-Containing Diet Inhibits Diethylnitrosamine-Induced Murine Hepatocarcinogenesis
, 2009 Curcumin has been widely used as a spice and coloring agent in foods. Recently, curcumin was found to possess chemopreventive effects against skin cancer, forestomach cancer, colon cancer and oral cancer in mice.
CHUANG, SHUANG-EN;KUO, MIN-LIANG;HSU, CHIH-HUNG;CHEN, CHI-LONG;LIN, JEN-KUN;LAI, GI-MING;HSIEH, CHANG-YAO;CHENG, ANN-LII +1 more
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Liver Carcinogenesis by Diethylnitrosamine in the Rat
Science, 1966 Diethylnitrosamine was continuously administered to rats at a dose rate of low toxicity. Ninety-two percent of the animals died with multicentrical hepatocellular carcinomata within a narrow and highly reproducible time interval. Discontinuing the carcinogen during the experiment resulted in a prolonged median time until death, a reduced tumor yield ...
Rajewsky, M. +2 more
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Mouse Model of Diethylnitrosamine-Induced Gastric Cancer
Journal of Surgical Research, 2008Nitrosamines are associated with the potential to induce cancer in the digestive tract. Ethanol has also been shown to enhance the effects of nitrosamine-induced carcinogenesis. The aim of this study was to investigate a murine model of the prevalence and types of epithelial lesions induced in the stomach by diethylnitrosamine (DEN), and to evaluate ...
Maria Isabel Edelweiss
exaly +3 more sources
Heliyon, 2020 The generation of reactive oxygen species (ROS) plays an essential role in the pathogenesis of several diseases. Its implication in inflammation has suggested a possible link between oxidative stress and activation/release of cytokines in precancerous ...
E N Maduagwu, E N Maduagwu
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Studies on the Metabolism of Diethylnitrosamine in the Rat
Biochemical Society Transactions, 1975benzopyrene or phenobarbital was used in each case before adding an NADPHregenerating system and either microsomal or soluble fraction from avocado pear. The normal activities obtainable in the ‘microsomal’ and soluble fractions from avocado pear are illustrated in Table I .
J C, Phillips +4 more
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Diethylnitrosamine-induced liver tumorigenesis in mice
2021Hepatocellular carcinoma (HCC) is the fifth most common cancer worldwide and the third leading cause of cancer related mortality with a 10 year survival rate of merely 22-35%. Tumorigenesis frequently occurs in patients with chronic liver disease where continued liver cell damage, compensatory proliferation and inflammation provide the basis for tumor ...
Isabel, Schulien, Peter, Hasselblatt
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Occurrence of diethylnitrosamine in some samples of food
Food and Cosmetics Toxicology, 1968Summary The presence of diethylnitrosamine has been confirmed by thin-layer chromatography in some samples of wheat plant, wheat grain, wheat flour, milk and cheese.
L, Hedler, P, Marquardt
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