Results 91 to 100 of about 12,555 (220)
Water, Air and Soil Pollution, 2018 Diethylnitrosamine (DEN) is present in food, water, and daily supplies and is regarded as a toxicant of carcinogenicity. The developmental toxicity of DEN has been rarely reported as yet.
Danping Huang +5 more
semanticscholar +1 more source
Indian Journal of Health Sciences and Biomedical Research KLEU, 2016 Objective: This study aims to evaluate the role of Lycopersicon esculentum in diethylnitrosamine (DEN)-induced and phenobarbital (PB)-promoted hepatocellular carcinoma.
Bhrigu Kumar Das +2 more
doaj +1 more source
Helminths as architects of trained tolerance: implications for human health [PDF]
Clin Transl ImmunologyAbstract Helminths infect nearly 2 billion people worldwide and are a major cause of chronic morbidity in low‐resource regions. Unlike bacterial and viral pathogens that elicit protective memory, helminths actively remodel host immunity to enable their years‐long persistence and reinfection.
Moroz Q, Souza J, Briggs N.
europepmc +2 more sources
Bioactive Potentials of Longan (Dimocarpus longan) Fruit Juice vs Hepatic Carcinoma Initiated by Diethylnitrosamine in Rats [PDF]
مجلة بحوث التربية النوعيةThis research aimed to determine the potential role of longan fruit juice in inhibiting the process of hepatic carcinoma in diethylnitrosamine (DEN)-induced rats and enhancing liver recovery. The treatment used two dosages, 100mg/kg/day and 200mg/kg/day,
Nanees Youssef Elmatwally Elsayed Awad +1 more
doaj +1 more source
BMC Gastroenterology, 2016 BackgroundThe incidence of hepatocellular carcinoma with nonalcoholic steatohepatitis is increasing, and its clinicopathological features are well established.
Norihiro Kishida +11 more
semanticscholar +1 more source
Diethylnitrosamine and Other N-Nitrosamines in Foods
Journal of AOAC INTERNATIONAL, 1969 Abstract Dimethyl-, diethyl-, di-n-propyl, and other nitrosamines in foods are determined semiquantitatively as follows: (a) initial extraction of the nitrosamines from foods into suitable solvents, (b) isolation of the nitrosamines from other interfering materials by steam distillation and ion exchange cleanup, (c) detection and ...
J J Marleau +3 more
openaire +1 more source
Deletion of sphingosine kinase 1 inhibits liver tumorigenesis in diethylnitrosamine-treated mice
OncoTarget, 2018 Primary liver cancer is the 3rd leading cause of cancer deaths worldwide with very few effective treatments. Sphingosine kinase 1 (SphK1), a key regulator of sphingolipid metabolites, is over-expressed in human hepatocellular carcinoma (HCC) and our ...
Jinbiao Chen +11 more
semanticscholar +1 more source
Diethylnitrosamine (DENA) recapitulates formation of hepatic angiosarcoma in pigs.
PLoS ONE, 2019 Background & aimPrimary hepatic angiosarcoma is a rare tumor with poor prognosis. The aim of this study was to generate a new angiosarcoma model to improve research on hepatic angiosarcoma.MethodsPigs sus scrofa were treated with different regimens of ...
Sonja M Kessler +10 more
doaj +1 more source
Apigenin enhances sorafenib anti-tumour efficacy in hepatocellular carcinoma
Translational OncologyBackground: The “one drug-one target” paradigm has various limitations affecting drug efficacy, such as resistance profiles and adverse effects. Combinational therapies help reduce unexpected off-target effects and accelerate therapeutic efficacy ...
Deepti Singh +6 more
doaj +1 more source