Results 41 to 50 of about 24,189 (241)
Setting cutoff values for continuous variables associated with hepatocarcinogenesis.
, 2022 Setting cutoff values for continuous variables associated with hepatocarcinogenesis.
Tsutomu Tamai (496424) +21 more
core +1 more source
Mitochondrial IRG1 traps MCL-1 to induce hepatocyte apoptosis and promote carcinogenesis
Cell Death and Disease, 2023 Hepatocarcinogenesis is initiated by repeated hepatocyte death and liver damage, and the underlying mechanisms mediating cell death and the subsequent carcinogenesis remain to be fully investigated.
Liyuan Zhang +17 more
doaj +1 more source
Biomedicines, 2021 The clinical significance of mac-2 binding protein glycosylation isomer (M2BPGi) levels based on virological responses due to antiviral therapy has not been fully evaluated.
Satoshi Takakusagi +7 more
doaj +1 more source
Genetic mechanisms of hepatocarcinogenesis [PDF]
Oncogene, 2002 The development of hepatocellular carcinoma (HCC) is a multistep process associated with changes in host gene expression, some of which correlate with the appearance and progression of tumor. Preneoplastic changes in gene expression result from altered DNA methylation, the actions of hepatitis B and C viruses, and point mutations or loss of ...
Mark A, Feitelson +5 more
openaire +2 more sources
Post-translational Modification Control of HBV Biological Processes
Frontiers in Microbiology, 2018 Hepatitis B virus infection remains a global healthy issue that needs to be urgently solved. Novel strategies for anti-viral therapy are based on exploring the effective diagnostic markers and therapeutic targets of diseases caused by hepatitis B virus ...
Fan Yang
doaj +1 more source
Molecules, 2021 Cratoxylum formosum ssp. pruniflorum (Kurz) Gogelein (CP) is an indigenous plant found mainly in southeast Asia. Several in vitro studies have confirmed its activity against hepatocellular carcinoma; however, in vivo studies of the effect of CP on liver ...
Piman Pocasap +2 more
doaj +1 more source
Hepatitis C Virus-Induced Mitochondrial Dysfunctions
Viruses, 2013 Chronic hepatitis C is characterized by metabolic disorders and a microenvironment in the liver dominated by oxidative stress, inflammation and regeneration processes that lead in the long term to hepatocellular carcinoma.
Birke Bartosch +2 more
doaj +1 more source
Contributions of Activated Hepatic Stellate Cells to Hepatocarcinogenesis [PDF]
, 2015 Hepatocellular carcinoma (HCC), the second leading cause of worldwide cancer mortality, develops almost exclusively in patients with chronic liver disease.
Dapito, Dianne Helerie
core +1 more source
Oxidative stress and hepatocarcinogenesis
Hepatoma Research, 2018 Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related deaths worldwide. There are two major challenges for HCC, the first being that early detection is generally not applicable, and secondly, it is usually fatal within several months after diagnosis. HCC is an inflammation-induced cancer.
Fu, Ying, Chung, Fung-Lung
openaire +3 more sources
Mir-21 Suppression Promotes Mouse Hepatocarcinogenesis. [PDF]
, 2021 The microRNA 21 (miR-21) is upregulated in almost all known human cancers and is considered a highly potent oncogene and potential therapeutic target for cancer treatment.
Maeder, C. +48 more
core +2 more sources