Results 171 to 180 of about 118,409,845 (279)

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

Metabolic dysfunction-associated steatotic liver disease: pathogenic mechanisms and exercise-induced molecular adaptations. [PDF]

Lipids Health Dis
Lei S, Tao J, Chen X, Li X, Zhong S.
europepmc   +1 more source

Styrene and its natural analogues: accumulation and sustainable production methods

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Styrene, also known as vinyl benzene, is a colourless, highly volatile petrochemical that serves as a key monomer in the production of polystyrene and styrene‐butadiene rubber. Its industrial synthesis via the alkylation of benzene with ethylene relies on fossil fuels, requiring high temperatures and toxic catalysts that contribute to ...
Mwafaq Ibdah, Giovanni D'Ambrosio, Prasada Rao Kongala, Sureshkumar Mesara, Annalisa Serio, Bharadwaj Revuru, Antonello Paparella   +6 more
wiley   +1 more source

Neonatal Hyperinsulinemia and Maternal Diabetes Associated With a Hepatocyte Nuclear Factor 4 Alpha (HNF4A) Variant. [PDF]

Cureus
Takasugi Y, Nakagawa R, Ono H, Nakajima Y, Takasawa K.   +4 more
europepmc   +1 more source

Hepatic Adenomas in Men: Diagnostic Considerations and Management in the Modern Era

Journal of Surgical Oncology, EarlyView.
ABSTRACT Hepatic adenomas (HAs) are rare benign liver tumors traditionally associated with young women, yet contemporary epidemiologic trends reveal increasing recognition among men. Historically, universal resection in males has been recommended because of a nearly tenfold increased risk of malignant transformation as reported by Farges et al.
Teresa Belledent, Julie Nwosu, Kiers Brevik, Raegen M. Abbey, Timothy Pawlik, Dae Sun Hwang, Terry L. Hayes, Ikenna Nwosu, Mohammed O. Suraju, Hassan Aziz   +9 more
wiley   +1 more source

Metabolic-epigenetic regulation of the HBV cccDNA reservoir: pathways underpinning viral persistence. [PDF]

Front Microbiol
Peng Q, Hao L, Li S, Yu F, Li N, Ye F, Hu X.   +6 more
europepmc   +1 more source

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Hepatoprotective effects of resolvin D1 in mice exposed to ethanol and galactosamine. [PDF]

Hepatol Commun
Hardesty J, Warner J, Warner D, Treves R, Butzke-Souza N, Wang J, Abdelfadil Y, Gondim D, McClain C, Kirpich I.   +9 more
europepmc   +1 more source

Kaempferol Attenuates Myocardial Ischemia–Reperfusion Injury by Suppressing Ferroptosis via the KEAP1–Nrf2–GPX4 Axis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Myocardial ischemia/reperfusion (I/R) injury is characterized by cardiomyocyte death, excessive oxidative stress, inflammation, and ferroptosis, which collectively limit the efficacy of reperfusion therapy. In this study, we investigated whether kaempferol (KAE), a natural flavonol with antioxidative and antiinflammatory properties, could ...
Yan‐Bo Zhao, Ling‐Ling Sun, Xiao‐Hua Shen, Min Wang, Mei‐Hui Wang, Lu‐Lu Liu, Kai Zhang   +6 more
wiley   +1 more source

β-Catenin Signaling in Hepatocellular Carcinoma: Mechanisms of Therapeutic Resistance and Emerging Therapeutic Strategies. [PDF]

Curr Oncol
Chambers A, Reeves M, Shrestha A, Yarrapatni S, Duarte S, Zarrinpar A.   +5 more
europepmc   +1 more source