Results 221 to 230 of about 79,825 (316)

Establishment and Comparative Analysis of Radiation‐Induced Liver Disease in Normal and Fibrotic Rat Models

Precision Radiation Oncology, EarlyView.
This study successfully established two novel rat models of radiation‐induced liver disease (RILD), one in healthy livers and the other in TAA‐induced fibrotic livers, providing valuable insights into the combined effects of radiation and pre‐existing fibrosis.
Yanting Jiang, Yuxi Ding, Fang Wang, Danni Chen, Weixiang Zhong, Zhongjie Lu, Yixiang J. Wang, Senxiang Yan, Xiaoguang Liu, Feng Zhao   +9 more
wiley   +1 more source

Engineering Liver-Specific Promoters: A Comprehensive Review of Design, Mechanisms, and Clinical Applications in Gene Therapy. [PDF]

Cells
Artemyev V, Paremskaia AI, Dzhioeva AA, Mishina D, Bogdanov V, Krupinova J, Mazloum A, Feoktistova SG, Mityaeva ON, Volchkov PY.   +9 more
europepmc   +1 more source

Constitutive Photomorphogenesis Protein 1 homolog (COP1) sustains nuclear factor-4 alpha function in human hepatocyte models [PDF]

Sébastien Soubeyrand, Paulina Lau, Ruth McPherson, Ruth McPherson, Ruth McPherson   +4 more
openalex   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Exploring the role of cellular plasticity in metabolic dysfunction-associated steatosis and related molecular mechanisms. [PDF]

J Transl Med
Ercin M, Gezginci-Oktayoglu S.
europepmc   +1 more source

Purification and biochemical characterization of hepatocyte nuclear factor 2 involved in liver-specific transcription of the human alpha 1-antitrypsin gene.

, 1990
Vangipuram S. Rangan, Gautam Das
openalex   +1 more source

Precision mRNA Delivery via Ultrasound‐Controlled Release Perfluorocarbon Emulsions: An Innovative Ultrasound Theranostic Strategy with 19F MRI Feasibility

Small, EarlyView.
A key challenge in advancing messenger RNA (mRNA) therapeutics in cardiovascular diseases lies in achieving controlled release at the precise site within the vasculature. This study presents the development of perfluorocarbon nanodroplets with exceptional theranostic potential, enabling real‐time tracking through ultrasound and fluorine‐19 (19F ...
Haikun Liu, Mark Louis P. Vidallon, Yuyang Song, Aidan P. G. Walsh, Henry Gordon, Shulei Ren, Pengkai Shi, Bangyan Xu, Mitchell J. Moon, Sylvain Trépout, Rico F. Tabor, Alexis I. Bishop, Ulrich Flögel, Karlheinz Peter, Xiaowei Wang   +14 more
wiley   +1 more source

Sepsis and the Liver. [PDF]

Diseases
Geladari EV, Kalergi AC, Evangelopoulos AA, Sevastianos VA.   +3 more
europepmc   +1 more source

Multiple hepatocyte-enriched nuclear factors function in the regulation of transthyretin and alpha 1-antitrypsin genes.

, 1989
Robert H. Costa, Dennis R. Grayson, James Darnell   +2 more
openalex   +2 more sources

Volumetric Single‐Molecule Tracking Inside Subcellular Structures

Small, EarlyView.
This correlative microscopy approach integrates single‐molecule light‐field microscopy (SMLFM) with widefield Fourier light‐field microscopy (FLFM) to enable 3D single‐molecule tracking within the organelles of living mammalian cells. Instantaneous volumetric segmentation enhances the sensitivity of molecular organization and diffusion measurements ...
Sam Daly, Joseph E. Chambers, Caroline Jones, Bin Fu, James D. Manton, Joseph S. Beckwith, Stefan J. Marciniak, David C. Gershlick, Steven F. Lee   +8 more
wiley   +1 more source