Results 231 to 240 of about 334,700 (354)

Constitutive androstane receptor, liver pathophysiology and chemical contaminants: current evidence and perspectives. [PDF]

Front Endocrinol (Lausanne)
De Battistis F, Djordjevic AB, Saso L, Mantovani A.   +3 more
europepmc   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Beneficial Effects of Infiltration of Platelet-Rich Plasma in the Endometrium. [PDF]

Biology (Basel)
Alonso-Frías P, Francés-Herrero E, Bueno-Fernandez C, Gómez-Álvarez M, Agustina-Hernández M, Cervelló I, Cozzolino M.   +6 more
europepmc   +1 more source

ATT-Myc Transgenic Mouse Model and Gene Expression Identify Genotoxic and Non-Genotoxic Chemicals That Accelerating Liver Tumor Growth in Short-Term Toxicity. [PDF]

Biomedicines
Elalfy M, Borlak J, Aljazzar AJ, Elhadidy MG.   +3 more
europepmc   +1 more source

Acute kidney injury and iron metabolism: A narrative review focusing on pathophysiology and therapy

Smart Molecules, EarlyView.
Schematic illustration of acute kidney injury and iron metabolism (By Figdraw). Image for iron metabolism, including uptake, storage, utilization, export: Reproduced with permission. Abstract Acute kidney injury (AKI) represents a substantial challenge to public health and is characterized by elevated occurrence and fatality rates.
Xinyu Tan, Man Li, Jing Chen, Gang Liu, Zhixiang Lu   +4 more
wiley   +1 more source

Risk factors for non-responsiveness to 5-aminosalicylic acid in patients with ulcerative colitis identified using retrospective clinical study and Mendelian randomization. [PDF]

Sci Rep
Ye ZN, Liu XT, Gu YM, Mao SX, Liang DH, Zhan K, Lei HQ, Huang SG.   +7 more
europepmc   +1 more source

Complex‐mediated nucleophilic aromatic substitution with aryl nitriles to realize intramolecular flapping‐restricted D‐A AIEgens for bioimaging

Smart Molecules, EarlyView.
In this work, we developed a complex‐mediated nucleophilic aromatic substitution which can generate rich D‐A AIEgens under a facile condition. The AIE mechanism of such AIEgens was unveiled and their application towards fatty liver imaging was exhibited. Abstract Donor‐acceptor (D‐A) compounds are particularly important in optoelectronic and biological
Feng Liu, Junkai Liu, Junyi Gong, Runfeng Lin, Siyuan Qiu, Zicheng Liu, Chongyang Li, Miao Meng, Shijie Li, Mei Tu, Jacky W. Y. Lam, Guangle Niu, Ming Chen   +12 more
wiley   +1 more source

Role of HNF6 in liver homeostasis and pathophysiology. [PDF]

Mol Med
Tian M, Gao W, Ma S, Cao H, Zhang Y, An F, Qi J, Yang Z.   +7 more
europepmc   +1 more source

Native and Engineered Extracellular Vesicles for the Treatment of Acute Lung Injury and Acute Respiratory Distress Syndrome

Small Science, EarlyView.
Both native and engineered extracellular vesicles (EVs) are served as promising therapeutic agents for treating acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). To circumvent the limitations of native EVs, various engineering strategies are adopted.
Zhengyan Gu, Wenjun Xue, Guanchao Mao, Zhipeng Pei, Jingjing Li, Mingxue Sun, Xinkang Zhang, Shanshan Zhang, Songling Li, Jinfeng Cen, Kai Xiao, Ying Lu, Qingqiang Xu   +12 more
wiley   +1 more source

Extracellular vesicle-mediated bidirectional communication between the liver and other organs: mechanistic exploration and prospects for clinical applications. [PDF]

J Nanobiotechnology
Mo W, Peng Y, Zheng Y, Zhao S, Deng L, Fan X.   +5 more
europepmc   +1 more source