Results 261 to 270 of about 79,825 (316)

Mitochondria-derived peptides in liver disease: Emerging regulators of hepatic metabolism and therapeutic targets. [PDF]

Hepatol Commun
Thoudam T, Zeng G, Gao H, Jiang Y, Huda N, Yang Z, Ma J, Liangpunsakul S.   +7 more
europepmc   +1 more source

High cholesterol absorption efficiency interferes with bile acid metabolism and cholesterol elimination from the body

Journal of Internal Medicine, EarlyView.
Abstract Background Elevated low‐density lipoprotein (LDL) cholesterol causes atherosclerotic cardiovascular diseases. Variables of whole‐body cholesterol metabolism, for example, high cholesterol absorption efficiency, might also be atherogenic, whereas the role of bile acids is controversial.
Piia Simonen, Ingmar Wester, Jyri Lommi, Juha Sinisalo, Helena Gylling   +4 more
wiley   +1 more source

3D co-cultures of primary human hepatocytes and Kupffer-like cells to address innate immune responses to rAAV. [PDF]

Sci Rep
Ramella Gal I, Arez F, Correia IP, Domenici G, Fernandes S, Silva G, Saldanha I, Duarte N, Freitas C, Alves PM, Maier U, Coroadinha AS, du Plessis F, Brito C.   +13 more
europepmc   +1 more source

Mechanistic insights into hepatic cell type-specific contributions to acetaminophen-induced acute liver injury. [PDF]

World J Gastroenterol
Yang D, Kim B, Kim JW.
europepmc   +1 more source

IMT504 accelerates post-hepatectomy liver regeneration in mice with involvement of GLAST + Wnt1 + bone marrow stromal progenitors. [PDF]

Sci Rep
Borda M, Cafaro L, Sierra R, Díaz Pedraza M, Becerra C, Ábalo A, Karolewski MJ, Cantero MJ, Schiavone M, Mazzolini GD, Montaner A, Fiore EJ, Aquino JB.   +12 more
europepmc   +1 more source

Bisphenol F and Steatotic Liver Disease: Resolving the PXR Paradox Through Stress Pathway Mechanisms. [PDF]

Biomedicines
AbdalHussin EA, Abd Hamid Z, Md Idris MH, Omar MH, Taib IS.   +4 more
europepmc   +1 more source

Unravelling the reversion mechanisms of activated hepatic stellate cell properties by extracellular vesicles from mesenchymal stem cells. [PDF]

World J Stem Cells
Islam MA, Mawya J, Salma U, Abu Kasim NH, Haque N.   +4 more
europepmc   +1 more source

Metabolomic analysis of the Hepatocyte Nuclear Factor 1 Alpha knockout mouse

The FASEB Journal, 2010
Genomic mutations in the transcription factor hepatocyte nuclear factor 1 alpha ( HNF1α ) result in maturity‐onset diabetes of the young type 3 (MODY3), a form of non‐insulin dependent diabetes mellitus (NIDDM). In addition, Hnf1α was identified
Jessica A. Bonzo, Andrew D. Patterson, Kristopher W. Krausz, Frank J. Gonzalez   +3 more
openalex   +2 more sources

Polymorphismen von HNF1alpha (hepatocyte nuclear factor 1 alpha) bei Gallensteinträgern

Zeitschrift für Gastroenterologie, 2011
Eine Ursache der Gallensteinentstehung kann auf genetische Dispositionen zuruckgefuhrt werden. Der ileale Gallensauretransporter ASBT (apical sodium-dependent bile acid transporter) ist bei Gallensteintragerinnen signifikant erniedrigt (Bergheim, J. Lipid Res. 2006) und zeigt eine genetische Assoziation (Renner, PLoS ONE, 2009) zu Cholelithiasis.
Diana Richter, Simone Harsch, Satoko Hirobe-Jahn, André Strohmeyer, Selma R. Schimmel, EF Stange   +5 more
openalex   +2 more sources

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Hepatic expression of cytochrome P450s in hepatocyte nuclear factor 1-alpha (HNF1α)-deficient mice

Biochemical Pharmacology, 2003
Hepatocyte nuclear factor 1 alpha (HNF1alpha) is a liver enriched homeodomain-containing transcription factor that has been shown to transactivate the promoters of several cytochrome P450 (CYP) genes, including CYP2E1, CYP1A2, CYP7A1, and CYP27, in vitro.
Connie, Cheung, Taro E, Akiyama, Gen, Kudo, Frank J, Gonzalez   +3 more
openaire   +2 more sources