Results 21 to 30 of about 89,971 (313)

Immunocytochemical hepatocyte nuclear factor-1.BETA. expression in effusions

The Journal of the Japanese Society of Clinical Cytology, 2010
T Machida, Masanori Yasuda, Michio SIMIZU, Norihide MOCHIZUKI, Kenji Kawai, Hitoshi Itoh, Hiroshi Kajiwara, Naoya Nakamura, Yoshiyuki Osamura   +8 more
openalex   +2 more sources

Functional regulatory roles of HNF1B in promoting cell proliferation, migration, invasion and fate decision of hepatocellular carcinoma [PDF]

BMC Cancer
Background Hepatocellular carcinoma (HCC) is a common malignant tumor worldwide, with complex pathogenesis and poor clinical prognosis. It was shown that hepatocyte nuclear factor 1β (HNF1B) is strongly expressed in hepatocyte and involved in liver ...
Piqian Zhao, Junda Li, Yingjie Xu, Jing Qu, Hongtao Zhang   +4 more
doaj   +2 more sources

Mutations in the Hepatocyte Nuclear Factor 1 Alpha (HNF1A), 4 Alpha (HNF4A) and 1 Beta (HNF1B) in Maturity-Onset Diabetes of the Young in Croatia

, 2019
Introduction: Maturity-onset diabetes of the young (MODY) is a monogenic form of diabetes that is characterized by an early onset (usually before 25 years), autosomal dominant mode of inheritance and a primary defect in pancreatic β-cell function. MODY is a common form of monogenic diabetes and it may account for 1% to 2% of all diabetes cases in ...
Domagoj Caban, Ana Merkler, Hana Ljubić, Anita Špehar Uroić, Nevena Krnić, Maja Čavlović Naglić, Lea Duvnjak, Darko Kaštelan, Jadranka Sertić   +8 more
  +6 more sources

Diagnostic value of dual detection of hepatocyte nuclear factor 1 beta (HNF-1β) and napsin A for diagnosing ovarian clear cell carcinoma. [PDF]

Int J Clin Exp Pathol, 2015
Li Q, Zeng X, Cheng X, Zhang J, Ji J, Wang J, Xiong K, Qi Q, Huang W.   +8 more
europepmc   +2 more sources

Function annotation of hepatic retinoid x receptor α based on genome-wide DNA binding and transcriptome profiling. [PDF]

, 2012
BackgroundRetinoid x receptor α (RXRα) is abundantly expressed in the liver and is essential for the function of other nuclear receptors. Using chromatin immunoprecipitation sequencing and mRNA profiling data generated from wild type and RXRα-null mouse ...
Fang, Jianwen, Fang, Yaping, He, Yuqi, Liu, Hui-Xin, Wan, Yu-Jui Yvonne, Zhan, Qi   +5 more
core   +11 more sources

Maturity‐onset diabetes of the young type 5, presenting as diabetic ketoacidosis with alkalemia: A report of a case

Journal of Diabetes Investigation, 2022
A 34‐year‐old man visited our Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan, because of dry mouth and weight loss.
Akiko Hayakawa‐Iwamoto, Daisuke Aotani, Yuki Shimizu, Shota Kakoi, Chie Hasegawa, Shunsuke Itoh, Asami Fujii, Katsushi Takeda, Takashi Yagi, Hiroyuki Koyama, Kenro Imaeda, Kandai Nozu, China Nagano, Hiromi Kataoka, Tomohiro Tanaka   +14 more
doaj   +1 more source

Hepatocyte nuclear factor 1β controls nephron tubular development [PDF]

Development, 2013
Nephron morphogenesis is a complex process that generates blood-filtration units (glomeruli) connected to extremely long and patterned tubular structures. Hepatocyte nuclear factor 1β (HNF1β) is a divergent homeobox transcription factor that is expressed in kidney from the first steps of nephrogenesis.
Massa, F., Garbay, S., Bouvier, R., Sugitani, Y., Noda, T., Gubler, M.-C., Heidet, L., Pontoglio, M., Fischer, E.   +8 more
openaire   +2 more sources

Human hepatocyte nuclear factor-1β (HNF1B) 1968A/G polymorphism [PDF]

Journal of Human Genetics, 2000
We found a novel A-->G change at nucleotide 1968 within the 3'-untranslated region of the HNF1B gene encoding the hepatocyte nuclear factor-1 beta. The HNF1B 1968A/G polymorphism could be detected by digestion with endonuclease MspI. The frequency of the HNF1B 1968G allele was 0.060 in Caucasians and 0.129 in Canadian Oji-Cree.
H, Cao, R A, Hegele
openaire   +2 more sources

Serum transferrin as a biomarker of hepatocyte nuclear factor 4 alpha activity and hepatocyte function in liver diseases

BMC Medicine, 2021
Background Serum transferrin levels represent an independent predictor of mortality in patients with liver failure. Hepatocyte nuclear factor 4 alpha (HNF4α) is a master regulator of hepatocyte functions.
Nurdan Guldiken, Josepmaria Argemi, Berivan Gurbuz, Stephen R. Atkinson, Martin Oliverius, Petr Fila, Karim Hamesch, Tony Bruns, Joaquín Cabezas, Juan J. Lozano, Jelena Mann, Sheng Cao, Philippe Mathurin, Vijay H. Shah, Christian Trautwein, Mark R. Thursz, Ramon Bataller, Pavel Strnad   +17 more
doaj   +1 more source

Failure to Thrive in a Middle-Aged Female: A Case of Congenital Incomplete Pancreas From a Rare Genetic Defect

Journal of Investigative Medicine High Impact Case Reports, 2023
Hepatocyte nuclear factor-1 beta (HNF1B) gene is predominantly expressed in the liver, kidney, lung, genitourinary tract, and pancreas. It is an important transcription factor that regulates pancreas development.
Onyinye Ugonabo MD, Turki Mohamed MD, Murad Kheetan MD, Ahmed Sherif MD   +3 more
doaj   +1 more source