Results 211 to 220 of about 86,113 (258)

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, EarlyView.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

Altered Bile Acid Transport in Liver Disease. [PDF]

Biomedicines
Cayton S, Czuba LC.
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Glycyrrhizin preparations in liver diseases: a narrative review of mechanisms and therapeutic potential. [PDF]

Front Pharmacol
Ma T, Hao H, Wang S, Qiu D, Cao W, Deng W, Wang S, Li X, Zhang Z, Wei X, Yao L, Gao Z, Yi W, Liu R, Li M.   +14 more
europepmc   +1 more source

A 3D bioengineered human liver for the study of acute and chronic drug-induced hepatotoxicity and fibrosis. [PDF]

Front Bioeng Biotechnol
Ferret-Miñana A, Alcaraz E, Horrillo R, Ramón-Azcón J, De Chiara F.   +4 more
europepmc   +1 more source

Hepatocyte-Derived Apoptotic Bodies as Pathological Intercellular Messengers in the Liver. [PDF]

Biomolecules
New-Aaron M, Adepoju LA, Pathania AS, Kharbanda KK, Osna NA.   +4 more
europepmc   +1 more source

An artificial intelligence optimized hepatic differentiation unveils NR5A2 and AP-1 transcriptional regulation in hepatic maturation. [PDF]

J Biol Chem
Huo Z, Tu J, Yang WL, Huang MF, Wang R, Chu CW, Xu A, Yu Y, Tavakol TN, Kizilbash M, Fisher ME, Huang YW, Zhu D, Phan TTT, Shoemaker R, Chen YW, Zhang Y, Huff CD, Chen SY, Liu TJ, Xiao H, Lee DF, Zhao R.   +22 more
europepmc   +1 more source

A comparative analysis of three distinct rehydrating solutions for addressing liver tissue desiccation resulting from dehydration failure. [PDF]

PeerJ
Shi W, Fu G, Shi H, Qi H, Fu H.
europepmc   +1 more source

Spatial hepatology: Decoding liver zonation for metabolic and regenerative therapeutics (Review). [PDF]

Int J Mol Med
Chen G, Jia H, Zhao K, Gao C, Liu Y, Zhu H, Yang D, Cai Y.   +7 more
europepmc   +1 more source