Results 311 to 320 of about 868,517 (361)

Dihydromyricetin ameliorates lipopolysaccharide‒induced hepatic injury in chickens by activating the Nrf2/Keap1 pathway and regulating mitochondrial dynamics. [PDF]

Poult Sci
Yuan L, Jiang X, Ren Y, Ma B, Ji Z, Wang S, Hao B, Li C, Li R, Liu F.   +9 more
europepmc   +1 more source

Lipid Nanoparticles for Delivery of CRISPR Gene Editing Components

Small Methods, EarlyView.
The review presents a comprehensive overview of each component of lipid nanoparticles（LNPs）and their effects on editing efficiency. It specifically highlights strategies for achieving non‐liver delivery, aiming for broader applications in gene editing. Furthermore, this review summarizes the applications of LNPs in gene editing and offers insights for ...
Fan Wu, Nei Li, Yudian Xiao, Rohan Palanki, Hannah Yamagata, Michael J. Mitchell, Xuexiang Han   +6 more
wiley   +1 more source

Farnesoid X receptor‑driven metabolic plasticity: Bridging physiological adaptation and malignant transformation in lipid handling (Review). [PDF]

Int J Mol Med
Sun Y, Sun K, Ling H, Xia Q.
europepmc   +1 more source

Lipid Microparticle‐Based Phantoms Modeling Hepatic Steatosis for the Validation of Quantitative Imaging Techniques

Small Methods, EarlyView.
This paper presents a novel method for creating ultrasound phantoms that accurately replicate fat vesicle sizes encountered in Metabolic Dysfunction‐Associated Steatotic Liver Disease (MASLD). This approach can improve the understanding of liver fat measurement by creating ultrasound phantoms that link different quantitative imaging techniques to ...
Connor Endsley, Shariq Ali, Karim Salhadar, Adam Woodward, Shea Garland, Julien Santelli, Mehdi Zeighami Salimabad, Liqiang Ren, Takeshi Yokoo, Ivan M. Rosado‐Mendez, David T. Fetzer, Caroline de Gracia Lux   +11 more
wiley   +1 more source

A renal hyperechogenicity study: From the phenotype to the genotype in the mutation of hepatocyte nuclear factor-1 beta gene

Anales de Pediatría (English Edition), 2019
Pilar Ribes Hernández, Adoración Granados Molina, Alicia García Pérez, Saoud Tahsin Swafiri, Esther Pérez Carbajo   +4 more
doaj  

Alternative splicing: hallmark and therapeutic opportunity in metabolic liver disease. [PDF]

Gastroenterol Rep (Oxf)
Jiang M, Alqahtani SA, Seto WK, Yilmaz Y, Pan Z, Valenti L, Eslam M.   +6 more
europepmc   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

Small Methods, EarlyView.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai, Jiawen Wang, Zihuan Lin, Danni Yu, Hui Yang, Jinsong Wei, Xiaoyu Li, Hao Hu, Chao Ni, Bing Zhao   +9 more
wiley   +1 more source

Guarding the Endothelium: SOX17's Crucial Role in Pulmonary Hypertension. [PDF]

Am J Respir Cell Mol Biol
Zhang X, Dai Z.
europepmc   +1 more source

NETosis: A bridge between cancer and autoimmunity

Rheumatology &Autoimmunity, EarlyView.
Niloufar Orooji, Manouchehr Fadaee
wiley   +1 more source