Results 101 to 110 of about 127,242 (210)

Transcription factors of the Nuclear Factor I (NFI) family control hepatocyte differentiation and cytochrome P450 activity in human liver

Pharmacological Research
Interindividual variability in hepatic drug metabolism and transport is well-known, and genetic variation in pharmacogenes impacts the efficacy and safety of drug treatments.
Kathrin Klein, Oliver Burk, Roman Tremmel, Florian A. Buettner, Lea Kaestle, Werner Schroth, Thomas E. Muerdter, Diana Eccles, Anna-Christina Schmidt, Hanno Nieß, Ulrich M. Zanger, Matthias Schwab, Volker M. Lauschke   +12 more
doaj   +1 more source

Hepatocyte Nuclear Factor 1-β Gene Mutation: Brief Report and Review of Hepatic Involvement [PDF]

, 2018
Sandra Mabel Camacho-Gomez, Michael J. Nowicki   +1 more
openalex   +1 more source

Hepatocyte nuclear factor 4α multiple isoforms, their functions, and their interactomes [PDF]

, 2023
Jehison Alirio Herrera‐Pulido, François‐Michel Boisvert, François Boudreau   +2 more
openalex   +1 more source

Loss of PPARα function promotes epigenetic dysregulation of lipid homeostasis driving ferroptosis and pyroptosis lipotoxicity in metabolic dysfunction associated Steatotic liver disease (MASLD)

Frontiers in Molecular Medicine
Metabolic Dysfunction Associated Steatotic Liver Disease (MASLD) is a growing epidemic with an estimated prevalence of 20%–30% in Europe and the most common cause of chronic liver disease worldwide.
Claudia Theys, Tineke Vanderhaeghen, Tineke Vanderhaeghen, Evelien Van Dijck, Cedric Peleman, Cedric Peleman, Anne Scheepers, Joe Ibrahim, Ligia Mateiu, Steven Timmermans, Steven Timmermans, Tom Vanden Berghe, Tom Vanden Berghe, Tom Vanden Berghe, Sven M. Francque, Sven M. Francque, Wim Van Hul, Claude Libert, Claude Libert, Wim Vanden Berghe   +19 more
doaj   +1 more source

Hepatocyte Nuclear Factor 1-Alpha [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

Hepatocyte Nuclear Factor 1α Gene Inactivation Impairs Chromatin Remodeling and Demethylation of the Phenylalanine Hydroxylase Gene

, 1997
Marco Pontoglio, Daniela M. Faust, Antonia Doyen, Moshé Yaniv, Mary C. Weiss   +4 more
openalex   +2 more sources

Stimulation of hepatic regeneration after partial hepatectomy by infusion of a cytosol extract from regenerating dog liver [PDF]

, 1980
A cytosol liver extract was prepared from adult dog livers and from liver remnants that had been regenerating for one, two and three days after 72 per cent partial hepatectomy.
Hayashida, N, Moore, J, Patzelt, L, Porter, KA, Starzl, TE, Terblanche, J   +5 more
core  

Research progress of hepatocyte nuclear factor 4α in gastric cancer and precancerous lesions

Zhongguo linchuang yanjiu
Hepatocyte nuclear factor 4α (HNF4α) is a member of the nuclear receptor superfamily, a kind of protein that binds to a specific gene promoter. It controls the expression of functional genes and is also involved in the regulation of many cellular ...
YANG Yuyan, ZHAO Weihan, WANG Siyu, DONG Siqi
doaj   +1 more source

Maturity-Onset Diabetes of the Young Caused by a Balanced Translocation Where the 20q12 Break Point Results in Disruption Upstream of the Coding Region of Hepatocyte Nuclear Factor-4α (HNF4A) Gene [PDF]

, 2002
Anna L. Gloyn, Sian Ellard, Maggie Shepherd, R T Howell, Elizabeth M. Parry, Andrew Jefferson, Elaine R. Levy, Andrew T. Hattersley   +7 more
openalex   +1 more source

Roles of hepatocyte nuclear factors in hepatitis B virus infection. [PDF]

World J Gastroenterol, 2016
Kim DH, Kang HS, Kim KH.
europepmc   +1 more source