Results 51 to 60 of about 127,242 (210)

Supplementary Figure Legends from Regulation of α-Fetoprotein by Nuclear Factor-κB Protects Hepatocytes from Tumor Necrosis Factor-α Cytotoxicity during Fetal Liver Development and Hepatic Oncogenesis [PDF]

, 2023
Lakita G. Cavin, Venkatraman Manickam, Valentina M. Factor, Swayamjot Kaur, Insa S. Schroeder, Frank Mercurio, Amer A. Beg, Snorri S. Thorgeirsson, Marcello Arsura   +8 more
openalex   +1 more source

Diazoxide-responsive hyperinsulinemic hypoglycemia caused by HNF4A gene mutations [PDF]

, 2010
Objective: The phenotype associated with heterozygous HNF4A gene mutations has recently been extended to include diazoxide responsive neonatal hypoglycemia in addition to maturity-onset diabetes of the young (MODY).
Ashcroft, B Schwahn, Clayton, D Cody, Ellard, Freeman, G Mali, I Banerjee, J P H Shield, K Hussain, Molven, N Murphy, O Rubio-Cabezas, R R Kapoor, S E Flanagan, S Ellard, Stanley, T Akcay, T Siahanidou, Thomas   +19 more
core   +2 more sources

Hepatocyte-Conditional Knockout of Phosphatidylethanolamine Binding Protein 4 Aggravated LPS/D-GalN-Induced Acute Liver Injury via the TLR4/NF-κB Pathway

Frontiers in Immunology, 2022
Acute liver injury (ALI) is a disease that seriously threatens human health and life, and a dysregulated inflammation response is one of the main mechanisms of ALI induced by various factors.
Xiao-qin Qu, Qiong-feng Chen, Qiong-feng Chen, Qiao-qing Shi, Qian-qian Luo, Shuang-yan Zheng, Yan-hong Li, Liang-yu Bai, Shuai Gan, Xiao-yan Zhou, Xiao-yan Zhou   +10 more
doaj   +1 more source

77 Severe Hypomagnesemia in an HIV Patient due to Hepatocyte Nuclear Factor 1B Deletion [PDF]

, 2022

openalex   +1 more source

Reversible Nuclear-Lipid-Droplet Morphology Induced by Oleic Acid: A Link to Cellular-Lipid Metabolism [PDF]

, 2017
Neutral lipidsÐinvolved in many cellular processesÐare stored as lipid droplets (LD), thosemainly cytosolic (cLD) along with a small nuclear population (nLD).
Garcia, Margarita Maria, Lagrutta, Lucía Carolina, Layerenza, Juan Pablo, Montero Villegas, Sandra, Sisti, Martin Sebastian, Ves Losada, Ana   +5 more
core   +3 more sources

Deficiency of the purinergic receptor 2X7 attenuates nonalcoholic steatohepatitis induced by high-fat diet. possible role of the NLRP3 Inflammasome [PDF]

, 2017
Molecular mechanisms driving transition from simple steatosis to nonalcoholic steatohepatitis (NASH), a critical step in the progression of nonalcoholic fatty liver disease (NAFLD) to cirrhosis, are poorly defined. This study aimed at investigating the
Blasetti Fantauzzi, Claudia, Iacobini, Carla, Menini, Stefano, Pugliese, Giuseppe, Rossi, Chiara, Santini, Eleonora, Solini, Anna   +6 more
core   +3 more sources

Establishment of hepatitis model in rat liver induced by injecting extracted DNA: Histopathological study

Journal of Basic and Applied Zoology, 2016
Chronic inflammatory liver diseases can be induced by viral infections, toxic-metabolic factors and/or autoimmune mechanisms. Inflammation or viral infection results in hepatocyte damage or cell lyses which cause DNA or other cell nuclear materials to be
Ahmed S. Ibraheem, Mohamed F. El-Sayed, Heba A. Khalil   +2 more
doaj   +1 more source

Post-translational deregulation of YAP1 is genetically controlled in rat liver cancer and determines the fate and stem-like behavior of the human disease [PDF]

, 2016
Previous studies showed that YAP1 is over-expressed in hepatocellular carcinoma (HCC). Here we observed higher expression of Yap1/Ctgf axis in dysplastic nodules and HCC chemically-induced in F344 rats, genetically susceptible to hepatocarcinogenesis ...
Avila, Matias A., Berasain, Carmen, Brozzetti, Stefania, Calvisi, Diego F., Daino, Lucia, Demartis, Maria I., Feo, Claudio F., Feo, Francesco, Latte, Gavinella, Pascale, Rosa M., Porcu, Alberto, Seddaiu, Maria A., Simile, Maria M., Tomasi, Maria L.   +13 more
core   +2 more sources

The hepatocyte nuclear factor 1 homeobox A (HNF1A) gene polymorphism and AFP serum levels in Egyptian HCC patients

Egyptian Liver Journal
Background Hepatocyte nuclear factors were first identified as liver-enriched transcription factors that might participate in various activities related to the transcription of genes unique to the liver.
Hanan M. Bedair, Ibrahim El-Tantawy El Sayed, Olfat M. Hendy, Mohmed Abdel-Samiee, Islam Abd El Hamid El Sayad, Sally S. Mandour   +5 more
doaj   +1 more source

Age-related changes in bile acid synthesis and hepatic nuclear receptor expression [PDF]

, 2007
BACKGROUND:Recent data highlighted the role of nuclear receptors in the transcriptional regulation of the limiting enzyme of bile acid synthesis, cholesterol 7alpha-hydroxylase, in cellular and animal models.
Anzivino, Claudia, Bertolotti, Marco, Carulli, Lucia, Carulli, Nicola, Crestani, M, De Fabiani, E, Del Puppo, M, Gabbi, C, Godio, C, Loria, P, Macchioni, D, Mitro, N, Ricchi, M, Rossi, Aldo   +13 more
core   +1 more source