Results 71 to 80 of about 127,242 (210)

The adipokine sFRP4 induces insulin resistance and lipogenesis in the liver [PDF]

open access: yes, 2019
Secreted frizzled-related protein (sFRP) 4 is an adipokine with increased expression in white adipose tissue from obese subjects with type 2 diabetes and non-alcoholic fatty liver disease (NAFLD).
Al-Hasani, Hadi   +12 more
core   +1 more source

Hepatic Differentiation of Marmoset Embryonic Stem Cells and Functional Characterization of ESC-Derived Hepatocyte-Like Cells

open access: yesHepatic Medicine: Evidence and Research, 2020
Rajagopal N Aravalli,1 Daniel P Collins,2 Joel H Hapke,2 Andrew T Crane,3 Clifford J Steer4,5 1Department of Electrical and Computer Engineering, University of Minnesota, Minneapolis, MN 55455, USA; 2Cytomedical Design Group LLC, St. Paul, MN 55127, USA;
Aravalli RN   +4 more
doaj  

Efficient Production of Hepatocyte-like Cells from Human-induced Pluripotent Stem Cells by Optimizing Growth Factors

open access: yesInternational Journal of Organ Transplantation Medicine, 2018
Background: Generating hepatocytes with complete liver functions is still a challenge and developing more functional hepatocytes is needed. Objective: To compare various differentiation factors and protocols and introducing a preferable protocol to ...
Z Jaafarpour   +6 more
doaj  

A fresh look at augmenter of liver regeneration in rats. [PDF]

open access: yes, 1999
Augmenter of liver regeneration (ALR) is a hepatotrophic protein originally identified by bioassay in regenerating rat and canine livers following partial hepatectomy and in the hyperplastic livers of weanling rats, but not in resting adult livers.
Abyss   +86 more
core   +1 more source

Dual Role of HNF4α in Colorectal Adenocarcinoma During Carcinogenesis and Metastasis

open access: yesCells
Hepatocyte nuclear factor 4α (HNF4α), a highly conserved member of the nuclear receptor superfamily of transcription factors, has been identified as a promising therapeutic candidate for colorectal adenocarcinoma (CRAC). This study was to investigate the
Ju Seok Kim   +4 more
doaj   +1 more source

EZH2 RIP-seq Identifies Tissue-specific Long Non-coding RNAs. [PDF]

open access: yes, 2018
BackgroundPolycomb Repressive Complex 2 (PRC2) catalyzes histone methylation at H3 Lys27, and plays crucial roles during development and diseases in numerous systems.
He, Yuan   +9 more
core  

Hepatic progenitor cells from adult human livers for cell transplantation. [PDF]

open access: yes, 2008
Objective: Liver regeneration is mainly based on cellular self-renewal including progenitor cells. Efforts have been made to harness this potential for cell transplantation, but shortage of hepatocytes and premature differentiated progenitor cells ...
Aurich, H.   +10 more
core   +1 more source

HNF4A ameliorates acute liver failure by inhibiting NCOA4-mediated ferritinophagy

open access: yesScientific Reports
Intracellular iron homeostasis imbalance is linked to cellular ferroptosis and inflammatory injury diseases. NCOA4-mediated ferritin autophagy is vital for regulating intracellular iron homeostasis, but its impact on acute liver failure (ALF ...
Weiyan Yu, Caiyan Zhao
doaj   +1 more source

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