Results 101 to 110 of about 40,633 (246)

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

Cell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo, Xiaoya Zhang, Danmei Zhang, Chunxia Shi, Luwen Wang, Zuojiong Gong   +5 more
wiley   +1 more source

Extended Double Plasma Molecular Adsorption Sessions and Bilirubin Clearance: A Case Report

Hemodialysis International, EarlyView.
ABSTRACT Background The double plasma molecular adsorption system is an artificial‐liver treatment model combining the use of ion exchange resins and neutral microporous resins to remove toxins such as inflammatory cytokines without consuming large amounts of plasma and albumin. Given the relatively expensive consumables needed for Bilirubin adsorption,
Hui Ye, Yi Long Hao, Hai Nan Yang, Wei Fang Yuan, Kai Liang Xu, Xiao Xiao Li, Ming Lei, Yu Xia Sun   +7 more
wiley   +1 more source

Synergistic enhancement SPF from annatto seed oil and alkaline extracts in association with organic UV filters

International Journal of Cosmetic Science, EarlyView.
An SPF formulation incorporating Bixa orellana seed extracts and oils showed enhanced UV protection, highlighting the potential of natural bioactive compounds as effective boosters in photoprotective cosmetic products. Abstract Objective This study investigated the antioxidant activity of oil and alkaline aqueous extracts obtained from Bixa orellana ...
Ister Cordeiro Mariotini, Aliny Rodrigues de Jesus da Conceição, Rodrigo Rezende Kitagawa, Bernardo de Jesus Pavuna, Claudia Masrouah Jamal, Claudineia Aparecida Sales de Oliveira Pinto, André Rolim Baby, Fabiana Vieira Lima Solino Pessoa, Mariana Santos Pinheiro   +8 more
wiley   +1 more source

GLP‐1 RA Plus SGLT2i Versus Monotherapy in MASLD and Type 2 Diabetes: Three Pairwise Target Trial Emulations

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Introduction Glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) have demonstrated cardiovascular and metabolic benefits individually; however, the comparative effectiveness of combination therapy versus monotherapy in patients with metabolic dysfunction‐associated steatotic liver ...
Mohanad A. Alkuwaiti, Faisal A. Al‐Harbi, Ahmed K. Alsaif, Ziyad M. AlSughayyir, Rayan Saleh Alsaud, Mohammed N. Aljabr, Ahmad K. Alanazi, Ahmad A. Alosaily, Abdulrhman K. Alabdulqader, Hamza Almusabeh, Rayyan F. Altemani, Ahmed Y. Azzam   +11 more
wiley   +1 more source

Silibinin’s Effects against Methotrexate-Induced Hepatotoxicity in Adjuvant-Induced Arthritis Rat Model

Pharmaceuticals
Methotrexate (MTX) is the first drug of choice to treat several diseases, including rheumatoid arthritis. However, its administration is accompanied by severe side effects, most commonly hepatotoxicity.
Ghada Khawaja, Youmna El-Orfali
doaj   +1 more source

Orchid genome evolution and trait innovation

Journal of Integrative Plant Biology, EarlyView.
Orchids became one of the world's most diverse plant groups through genome‐driven innovations, unique relationships with fungi and pollinators, and remarkable adaptability. This review explains the origins of orchids and the evolution of their distinctive life forms, flowers, and ecological strategies and highlights promising directions for future ...
Meng‐Yao Zeng, Cheng‐Yuan Zhou, Linying Wang, Jie Gao, Weilun Yin, Dong‐Hui Peng, Siren Lan, Feng‐Xi Yang, Zhong‐Jian Liu   +8 more
wiley   +1 more source

Therapeutic potential of okra (Abelmoschus esculentus) in dysglycaemia and metabolic dysfunction: A systematic review and meta‐analysis across the diabetes spectrum

Experimental Physiology, EarlyView.
Abstract The aim of this systematic review and meta‐analysis was to evaluate comprehensively the therapeutic potential of Abelmoschus esculentus (okra) supplementation across the diabetes spectrum of key metabolic risk factors. A search was conducted in PubMed, Scopus, Web of Science, EMBASE and the Cochrane Library, up to 23 July 2025, to identify ...
Ali Jafari, Helia Mardani, Mohammad Amin Karimi, MohammadHossein Sahami Gilan, Helia Hemmat, Fatemeh Shoja, Nooshin Enayati Soofi, Ghazaleh Eslamian   +7 more
wiley   +1 more source

Metabolomic Mapping of Greek Olive Leaves by Untargeted NMR‐Based Profiling and LC–HRMS Dereplication

Analytical Science Advances, Volume 7, Issue 2, December 2026.
ABSTRACT Olive tree leaves are phytochemically rich yet insufficiently valorised in terms of systematic cultivar‐based characterisation and exploitation, and are an abundant olive industry side‐product. This study represents the first large‐scale metabolome mapping based on 340 leaf extracts from five major Greek cultivars (Amfissis, Koroneiki, Manaki,
Mariacaterina Lianza, Stavros Beteinakis, Vasileios Siderakis, Panagiotis Stathopoulos, Emmanuel Hatzakis, Maria Halabalaki   +5 more
wiley   +1 more source

Resveratrol: Advance on the Most Recent Research From 2021 to 2025

Phytochemicals in Food and Medicine, Volume 1, Issue 3, September 2026.
This review summarizes recent progress in resveratrol research (2021–2025), highlighting its natural sources, bioactivities, clinical evidence, and safety profiles. Resveratrol exerts multi‐target effects through the regulation of oxidative stress, inflammation, mitochondrial function, and gut microbiota.
Quanyong Wu, Boya Ouyang, Yi Yuan, Jesus Simal‐Gandara, Hui Cao   +4 more
wiley   +1 more source

Effects of Prenatal Ursodeoxycholic Acid and Probiotic Supplementation on Stress Parameters, Immune Response and Lamb Survival Rates in Ewes

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Prenatal ursodeoxycholic acid (UDCA) and probiotic supplementation, administered alone or combined, modulate colostrum quality and neonatal immunity in ewes. Combined UDCA + PRO most consistently increases colostral IgG, enhances neonatal IgG levels, and improves lamb survival.
M. Burak Ates, Fatih Aladag, Durmus Hatipoglu   +2 more
wiley   +1 more source