Results 111 to 120 of about 56,507 (292)

Anticancer potential of berberine: Molecular pathways and current clinical trial perspectives

JSFA reports, EarlyView.
Abstract Cancer is constantly rising mortality rates due to its late prognosis, poor management, and expensive treatment. Multi‐sectoral approaches for cancer management include hygienic practices, synthetic drug exploitation, radiation therapy, and diet modifications.
Muhammad Maaz, Muhammad Tauseef Sultan, Muhammad Israr, Waqas Ahmad Khan, Fahad Tanveer, Muzzamal Hussain, Muhammad Imran, Ahmed Mujtaba, Anjuman Gul Memon, Muhammad Atif, Entessar Al Jbawi   +10 more
wiley   +1 more source

The Hepatoprotective and Antioxidant Activities of Euphorbia Species [PDF]

, 2023
Liver diseases have become a major problem in the world. They generally cause about 2 million deaths per year worldwide. Euphorbia is the sixth largest genus among flowering plants, and the largest genus in Euphorbiaceae, with about 2160 species.
Joujeh, Ruba, Joujeh, Dima
core  

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source

Assessing the Antioxidant, Hepatoprotective, and Iron-Chelating Potential of Perilla frutescens Seed

Biomedicines
Background/Objectives: Iron overload is a serious condition that can increase the production of reactive oxygen species (ROS), leading to oxidative tissue damage and organ dysfunction.
Sirichatnach Pakdeepromma, Komsak Pintha, Payungsak Tantipaiboonwong, Chonthida Thephinlap, Maitree Suttajit, Sawaruj Kaowinn, Napapan Kangwan, Wanwisa Suwannaloet, Kanjana Pangjit   +8 more
doaj   +1 more source

Effects of catechins, resveratrol, silymarin components and some of their conjugates on xanthine oxidase‐catalyzed xanthine and 6‐mercaptopurine oxidation

Journal of the Science of Food and Agriculture, Volume 105, Issue 5, Page 2765-2776, 30 March 2025.
Abstract BACKGROUND Over the past two decades, the global incidence of gout has markedly increased, affecting people worldwide. Considering the side effects of xanthine oxidase (XO) inhibitor drugs (e.g. allopurinol and febuxostat) used in the treatment of hyperuricemia and gout, the potential application of phytochemicals has been widely studied.
Tímea Bencsik, Orsolya Balázs, Róbert G Vida, Balázs Z Zsidó, Csaba Hetényi, Kateřina Valentová, Miklós Poór   +6 more
wiley   +1 more source

Syzygium aqueum: A Polyphenol- Rich Leaf Extract Exhibits Antioxidant, Hepatoprotective, Pain-Killing and Anti-inflammatory Activities in Animal Models

Frontiers in Pharmacology, 2018
Syzygium aqueum is widely used in folk medicine. A polyphenol-rich extract from its leaves demonstrated a plethora of substantial pharmacological properties.
Mansour Sobeh, Mona F. Mahmoud, Ganna Petruk, Samar Rezq, Mohamed L. Ashour, Fadia S. Youssef, Assem M. El-Shazly, Daria M. Monti, Ashraf B. Abdel-Naim, Michael Wink   +9 more
doaj   +1 more source

Antioxidant and hepatoprotective activity of Cordia macleodii leaves [PDF]

, 2009
This investigation was undertaken to evaluate ethanolic extract of Cordia macleodii leaves for possible antioxidant and hepatoprotective potential. Antioxidant activity of the extracts was evaluated by four established, in vitro methods viz. 1,1-diphenyl-
Majid A. Haleem, Haleem, Majid A., Bhanudansh S. Kuchekar, Nadeem A. Logade, Kuchekar, Bhanudansh S., Logade, Nadeem A., Qureshi, Naseem N., Naseem N. Qureshi   +7 more
core   +1 more source

Biological activities and bioactive constituents of Flammulina velutipes: An updated systematic review

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Flammulina velutipes (enokitake) is an edible mushroom recognized for both its nutritional and medicinal properties. It exhibits a broad spectrum of biological activities, including antioxidant, anti‐inflammatory, antitumor, immunomodulatory, and gut microbiota‐regulating effects.
Rıdvan Özgen, Didem Şöhretoğlu, Ayşe Kuruüzüm‐Uz   +2 more
wiley   +1 more source

Therapeutic potential of caffeic acid and coumarin in modifying aluminum-induced hepatic injury in Wistar rats

Notulae Scientia Biologicae
Antioxidants and phenolic compounds have always been tested as chemoprotective agents to regulate disease progression related to oxidative stress. Through this study, we investigate the possible corrective effects of caffeic acid and coumarin against ...
Zehor CHOUARI, Omar KHAROUBI, Khadidja KESSAS, Wafaa LOUNIS, Anne VEJUX, Abdelkader AOUES   +5 more
doaj   +1 more source

Modulation of STAT6 signaling for hepatoprotection

Frontiers in Pharmacology
Signal transducer and activator of transcription (STAT) proteins are a family of seven transcription factors mediating various biological processes. STAT6 is classically known to regulate immune cell biology by transmitting signals from interleukin (IL)-4 and IL-13 into transcriptional activation of genes driving type 2 immunity.
Somm, Emmanuel, Rahman, Mahdi, Szanto, Ildiko, Gariani, Karim, Jornayvaz, François   +4 more
openaire   +2 more sources