Results 131 to 140 of about 40,633 (246)

<i>Juniperus phoenicea</i> L. Essential Oil from Ain El Orak (Algeria): Chemical Analysis by GC/MS, In Vitro Antioxidant and In Vivo/In Silico Gastroprotective and Hepatoprotective Effects. [PDF]

Foods
Medjekane M, Nait Bachir Y, Benyahlou ZD, Nemar F, Medjahed H, Haimoud SA, Sadoud M, Naas H, Nehari A, Mansouri M, Mimouni C, Chouaih A, Foligni R.   +12 more
europepmc   +1 more source

Zingerone Alleviates Acetaminophen‐Induced Liver Damage by Regulating Oxidative Stress, Inflammation, Apoptosis, Endoplasmic Reticulum Stress, and Autophagy

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Mechanism of action of zingerone on acetaminophen‐induced liver damage. ABSTRACT The aim of this study is to investigate the protective effect of zingerone (ZNG), an antioxidant agent, against acetaminophen (APAP)‐induced liver damage, which is used as an analgesic and antipyretic. For this purpose, twenty‐eight male rats were divided into four groups:
Serpil Aygörmez, Mustafa Makav, Sevda Eliş Yıldız, Elif Dalkılınç, Mushap Kuru, Şaban Maraşlı   +5 more
wiley   +1 more source

Network Pharmacology Analysis Reveals Multi-Target Hepatoprotective Mechanisms of a Multi-Component Pharmacopuncture Against Ephedra-Associated Liver Injury with Implications for Mitochondrial Quality Control. [PDF]

Medicina (Kaunas)
Hwang JH, Jung C.
europepmc   +1 more source

Rupatadine Ameliorates Cisplatin‐Induced Hepatotoxicity in Rats: Targeting HMGB1/TLR4/NF‐κB and NLRP3/Caspase‐1 Signaling Pathways

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Graphical representation of the probable mechanisms underlying the effect of RUPA on CISP‐evoked hepatotoxicity in rats. ABSTRACT Despite cisplatin (CISP) is broadly employed in cancer therapy, its adverse effects, involving hepatotoxicity, restrict its clinical usage.
Shaimaa Mohamed Abdelrahman, Amany Abdlrehim Bekhit, Olivia N. Beshay   +2 more
wiley   +1 more source

Hepatoprotective effects of mitoquinol mesylate in dogs with methylprednisolone acetate-induced steroid hepatopathy: A randomized crossover study. [PDF]

Vet World
Kondratjeva J, Nikolajenko M, Ilgaza A.
europepmc   +1 more source

Protective Role of Thymoquinone Against TCE‐Induced Liver Damage Through HSP70 Modulation

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Trichloroethylene, a widely encountered environmental toxicant, induces oxidative stress–mediated liver injury and elevated HSP70 expression. Thymoquinone markedly mitigated TCE‐induced hepatotoxicity in rats by reducing oxidative damage, suppressing inflammatory responses, and restoring liver histological integrity. ABSTRACT Trichloroethylene (TCE) is
Arzu Güneş, Neriman Çolakoğlu
wiley   +1 more source

Protective Effects of <i>Vitis coignetiae</i> Vine Stem Extract Against Carbon Tetrachloride-Induced Acute Liver Injury in Mice. [PDF]

Antioxidants (Basel)
Yoon NK, Lee J, Chung H, Kim JK, Ku SK.
europepmc   +1 more source

Resmetirom Ameliorates Fibrogenesis in Hepatic Stellate Cells via Thyroid Hormone Receptor Alpha‐Fatty‐Acid Amide Hydrolase 1 Signaling Pathway

MedComm, Volume 7, Issue 8, August 2026.
1. Resmetirom attenuates the activation of HSCs induced in in vitro and in vivo models. 2. Resmetirom attenuates the activation of HSCs through its specific action on the thyroid hormone receptor alpha. 3. Resmetirom requires fatty‐acid amide hydrolase 1 to reduce HSC activation. ABSTRACT Resmetirom is a liver‐directed, thyroid hormone receptor β (THRβ)
Eva Novoa, Alba Cabaleiro, Borja López‐Picallo, Natalia da Silva Lima, Cristina Riobello, Carmen Pena, Jose Iglesias‐Moure, Ana Senra, Maria Luz Martínez‐Chantar, Anabel Fernandez‐Iglesias, Jordi Gracia‐Sancho, Susana Bravo, Carlos Dieguez, Marta Varela‐Rey, Vincent Prevot, Markus Schwaninger, Miguel López, Rubén Nogueiras   +17 more
wiley   +1 more source

Citrus Peel Xanthophylls Orchestrate Lipid–Glucose–Inflammation Axis Reprogramming in Cardiometabolic Syndrome: Integrative In Silico and In Vivo Evidence

Molecular Nutrition &Food Research, Volume 70, Issue 15, 17 August 2026.
Central obesity and dyslipidaemia converge to impair insulin signalling and trigger chronic inflammation, oxidative stress, and mitochondrial dysfunction. This integrated metabolic disruption drives lipid imbalance, apoptosis, and persistent hyperglycaemia, ultimately accelerating the progression of type 2 diabetes and cardiovascular disease.
Muhammad Reva Aditya, Muhammad Yusuf, Kanandya Kizzandy, Rizki Hari Mulia, Agnes Vianne, Athaya Rahmanardi Muhammad, Davina Shafa Aviantiputri, Adha Fauzi Hendrawan, Ade Meidian Ambari, Dante Saksono Harbuwono, Antonello Santini, Fahrul Nurkolis   +11 more
wiley   +1 more source

Myo-Inositol: Pharmacokinetics, Biological Functions, and Therapeutic Potential in Liver Protection: Insights from Preclinical Models. [PDF]

Antioxidants (Basel)
Antonowski T, Osowski A, Wojtkiewicz J.
europepmc   +1 more source