Drug Delivery, 2021 Acne Vulgaris is one of the most common chronic inflammatory skin disorders that affect majority of teen-agers worldwide. Isotretinoin (ITT) is the drug of choice in the management of acne, but, it suffers from serious side-effects including ...
Khaled M. Hosny +2 more
doaj +1 more source
Hepatoprotective Effects of Bioflavonoid Luteolin Using Self-Nanoemulsifying Drug Delivery System
Molecules, 2021 Luteolin (LUT) is a natural pharmaceutical compound that is weakly water soluble and has low bioavailability when taken orally. As a result, the goal of this research was to create self-nanoemulsifying drug delivery systems (SNEDDS) for LUT in an attempt
F. Shakeel +8 more
semanticscholar +1 more source
Hepatoprotective Effects of Mushrooms [PDF]
Molecules, 2013 The particular characteristics of growth and development of mushrooms in nature result in the accumulation of a variety of secondary metabolites such as phenolic compounds, terpenes and steroids and essential cell wall components such as polysaccharides, b-glucans and proteins, several of them with biological activities.
Rosane Marina Peralta +6 more
openaire +3 more sources
Hepatoprotective and immunomodulatory effects of copper-nicotinate complex against fatty liver in rat model [PDF]
Veterinary World, 2019 Aim: The current study was designed to evaluate the potential hepatoprotective and immunomodulatory effects of copper-nicotinate complex (CNC) against methionine- and choline-deficient diet (MCDD)-induced fatty liver in rats.
Ahmed Medhat Hegazy +4 more
doaj +1 more source
Management of Hepatitis B with Siddha Medicine: A Case Report [PDF]
Journal of Clinical and Diagnostic ResearchHepatitis B is a viral disease that causes acute and chronic liver diseases. The Hepatitis B Virus (HBV) infects more than 300 million people worldwide, and over 686 billion people die every year due to its consequences.
Eswaran Chinraji +3 more
doaj +1 more source
FK 506 pre-treatment is associated with reduced levels of tumor necrosis factor and interleukin 6 following hepatic ischemia/reperfusion [PDF]
, 1993 Using a rat model, the effect of pre-treatment with FK 506 on hepatic ischemia/reperfusion injury was investigated. All control animals died within 72 h of the ischemia/reperfusion injury.
Aarden +64 more
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Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
Cytoprotective effects of melatonin against amitriptyline-induced toxicity in isolated rat hepatocytes [PDF]
, 2015 Purpose: Amitriptyline, one of the commonly used tricyclic antidepressants, caused rare but severe hepatotoxicity in patients who received it continuously. Previous findings showed that the intermediate metabolites of amitriptyline produced by CYP450 are
Dastmalchi, S. +3 more
core +1 more source
The In Vivo Antioxidant and Hepatoprotective Actions of Selected Chinese Teas
Foods, 2020 Tea is a popular beverage and shows very strong in vitro antioxidant activity. However, the relationship among in vitro and in vivo antioxidant activities in teas is seldom reported.
Shi-Yu Cao +9 more
semanticscholar +1 more source
Evaluation of Hepatoprotective Activities of Bryophyllum pinnatum Leaf Extract in Paracetamol Induced Toxicity in Wistar rats [PDF]
Trends in Pharmaceutical SciencesParacetamol-induced hepatotoxicity poses a significant health risk. Bryophyllum pinnatum (commonly known as "Never Die") has traditional medicinal applications, including potential hepatoprotective effects.
Odangowei Ogidi +2 more
doaj +1 more source