Results 31 to 40 of about 40,633 (246)

A Histopathological, Immunohistochemical and Biochemical Investigation on the in vitro Antioxidant, Myeloprotective, Hematoprotective and Hepatoprotective Effects of Hypericum triquetrifolium Seed Extract Against Cyclophosphamide-Induced Toxicity

Brazilian Archives of Biology and Technology
The aim of this study was to investigate in vitro antioxidant properties and in vivo protective effects of the methanol extract of the Hypericum triquetrifolium Turra (HT) seed against acute hepatotoxicity, myelotoxicity and hematotoxicity in rats ...
Songul Cetik Yildiz, Cumali Keskin, Varol Sahintürk, Adnan Ayhanci   +3 more
doaj   +1 more source

Hepatoprotective Effect of Kaempferol—A Review

Molecules
Liver diseases, including chronic inflammation and related metabolic dysfunction-associated steatotic liver disease (MASLD), fibrosis and cirrhosis remain a growing global health burden. Currently, available pharmacotherapy for liver dysfunction has limited efficacy.
Przemysław Niziński, Anna Krajewska, Tomasz Oniszczuk, Beata Polak, Anna Oniszczuk   +4 more
openaire   +3 more sources

Gut Microbiota, Immunity, and Metabolism in the Progression From Chronic Liver Disease to Hepatocellular Carcinoma

Advanced Science, EarlyView.
This review explains how chronic liver injury progresses toward hepatocellular carcinoma through interconnected changes in gut microbes, metabolism, immunity, fibrosis, and diet. It highlights microbial metabolites, bile‐acid signaling, immune dysfunction, and nutritional or microbiome‐based interventions as opportunities to identify risk earlier ...
Yi Hu, Caiyan Lin, Lijie Zhang, Xue Jiang, Huawen Li, Yangzhe Wu   +5 more
wiley   +1 more source

The efficacy of hepatic protectors in patients having chronic hepatitis

Бюллетень сибирской медицины, 2008
The purpose of the present work was the study of new hepatic protectors liproksol influence in the chronic hepatitis viral and alcohol etiology in comparison of carsil effect. 69 patients having chronic hepatitis were include in the investigation.
E. I. Beloborodova, A. I. Vengerovsky, I. K. Livshits, Ye. V. Beloborodova, V. A. Burkovskaya, D. I. Kuzmenko   +5 more
doaj   +1 more source

Hepatoprotective Herbs, Avicenna Viewpoint [PDF]

Iranian Red Crescent Medical Journal, 2014
Liver injury or dysfunction is considered as a serious health problem. The available synthetic drugs to treat liver disorders are expensive and cause further damage. Hence, hepatoprotective effects of some herbal drugs have been investigated, and one of the methods to choose herbs in order to study their biological effects is to search in ancient ...
Shamsi-Baghbanan, Hamid, Sharifian, Afsaneh, Esmaeili, Somayeh, Minaei, Bagher   +3 more
openaire   +2 more sources

A Microgel Platform Enables Site‐Specific Intestinal Delivery of Lactoferrin, Improving its Bioavailability for Targeted Alleviating Liver Injury and Colitis

Advanced Science, EarlyView.
This work first time reports an eco‐friendly desert plant food‐based polysaccharide ASKP microgels which have intestinal site‐specific release properties which can achieve small‐intestine or colon targeting capability via different cross‐linking chemistry.
Huiling Yan, Yixuan Li, Shanan Chen, Pengcheng Du, Kaiwen Wu, Hui Zhang, Kasper Hettinga, Lina Zhang, Gergely Toldi, Fazheng Ren, Yuan Li   +10 more
wiley   +1 more source

Targeting PLD3 Reverses the Immunosuppressive Niche by Reprogramming Tumor‐Associated Macrophages and Potentiates Antitumor Immunity

Advanced Science, EarlyView.
PLD3 activates the lysosomal‐AKT‐NF‐κB axis to drive cellular senescence in macrophages, establishing an immunosuppressive TME by limiting the infiltration of cytotoxic T, NK, and NKT cells, which confers resistance to anti‐PD‐1 therapy. Abrine inhibits PLD3 expression, restoring antitumor immunity and synergizing with anti‐PD‐1 treatment.
Xingtu Qin, Qiong Li, Xuemei Xu, Yuhan Wu, Yin Zhu, Jieqiong Wu, Yuan Fang, Qiubei Chen, Shuyang Wang, Jiang Yu, Yaping Ye, Hongli Jiao   +11 more
wiley   +1 more source

Response Surface Methodology Optimization on Ultrasonic‐Assisted Extraction of Chicory (Cichorium intybus L.) and Their UPLC‐ESI‐QTOF‐MS Analysis, Antioxidant and Hepatoprotective Activity

eFood
Chicory (Cichorium intybus L.) roots are commonly roasted and ground to produce a coffee alternative, valued for its robust, nutty taste and absence of caffeine. Historically, it has been utilized to facilitate digestion, serve as a diuretic, and promote
Aizhamal Baiseitova, Ulpan Amzeyeva, Aiya Tolepbergen, Yasmina Ulfanova, Yergazy Shybyray, Lixia Dai, Xiaofei Shang, Abdul Bari Shah, Jeong Yoon Kim, Janar Jenis   +9 more
doaj   +1 more source

Phytolacca dodecandra (Phytolaccaceae) Root Extract Exhibits Antioxidant and Hepatoprotective Activities in Mice with CCl4-Induced Acute Liver Damage

Clinical and Experimental Gastroenterology, 2021
Birhanu Geta Meharie,1 Tewodros Agedew Tunta2 1Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia; 2Department of Pharmacy, College of Medicine and Health Sciences, Arba Minch University, Arba Minch ...
Meharie BG, Tunta TA
doaj  

Secondary Metabolite Profiling, Anti-Inflammatory and Hepatoprotective Activity of Neptunia triquetra (Vahl) Benth

Molecules, 2021
The present study aimed to analyze the phytoconstituents of Neptunia triquetra (Vahl) Benth. Anti-inflammatory and hepatoprotective activities of ethanol (EE), chloroform (CE) and dichloromethane (DCME) of stem extracts were evaluated using in vivo ...
Nasir Aziz Wagay, Shah Rafiq, Mohammad Aslam Rather, Younas Rasheed Tantray, Feng Lin, Shabir Hussain Wani, Ahmed M. El-Sabrout, Hosam O. Elansary, Eman A. Mahmoud   +8 more
doaj   +1 more source