Results 21 to 30 of about 40,633 (246)

The Effect of Leunca Fruit (Solanum nigrum Linn) Infusion in Inhibiting the Increase of Serum Glutamate Pyruvate Transaminase Level in CCL4 Induced Hepatitis Wistar Rats

Althea Medical Journal, 2019
Background: Hepatitis may cause liver cell damage due to the oxidation processes and can be inhibited by antioxidant components. Antioxidant acts as hepatoprotector by slowing down the oxidation process.
Kuswinarti Kuswinarti, Syifa Karmani, Coriejati Rita   +2 more
doaj   +1 more source

Evaluation of Asparagus officinalis L. extract on hepatotoxicity induced by Senecio Vulgaris L. in Male Rats [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Liver disease is one of the global problems that are associated with high mortality. According to the WHO, about 500 million people are living with chronic hepatitis infection, which kills more than one million people a year ...
Fatemeh Moshtaghi, Mohammad Azadbakht, Soheil Azizi, Sobhan Sina, Fateme Alizade   +4 more
doaj  

Hepatoprotective and Antioxidant Potential of Phenolics-Enriched Fraction of Anogeissus acuminata Leaf against Alcohol-Induced Hepatotoxicity in Rats

Medical Sciences, 2022
Anogeissus acuminata is used to treat wounds, diarrhoea, dysentery, and skin ailments. However, its hepatoprotective effect against ethanol-induced liver damage is yet to be reported.
Lal Chand Pal, Shivankar Agrawal, Arti Gautam, Jayhind Kumar Chauhan, Chandana Venkateswara Rao   +4 more
doaj   +1 more source

Silymarin alleviates diclofenac-induced hepatotoxicity in male Wistar rats: Histopathological investigation

Open Veterinary Journal
Background: One of the primary concerns of the pharmaceutical industry is the potential for liver damage caused by drugs. Diclofenac is a member of the family ofnonsteroidall antiinflammatory medications (NSAIDs), which are known for their anti ...
Fawiziah Khalaf Alharbi
doaj   +1 more source

Hepatoprotective Natural Products

Archives of Pharmaceutical Sciences Ain Shams University, 2017
Egypt holds a unique position in the epidemiology of liver diseases and cancer. We, here, shed the light on some important plant extracts and pure compounds that could be used as a new building unit for treatment of liver diseases.
Omayma A. Eldahshan
doaj   +1 more source

Hepatoprotective potential of Decalepis hamiltonii (Wight and Arn) against carbon tetrachloride-induced hepatic damage in rats

Journal of Pharmacy and Bioallied Sciences, 2010
Hepatoprotective activity of the roots of Decalepis hamiltonii (Wight and Arn) was studied using carbon tetrachloride (CCl 4 ) induced liver injury model in albino rats.
R Harish, T Shivanandappa
doaj   +1 more source

Chrysophanol, Physcion, Hesperidin and Curcumin Modulate the Gene Expression of Pro-Inflammatory Mediators Induced by LPS in HepG2: In Silico and Molecular Studies

Antioxidants, 2019
Hepatitis is an inflammatory condition that can develop hepatocellular carcinoma. Traditional medicine has always been the pillar of medical practice.
Nabil Mohamed Selim, Abdullah Abdurrahman Elgazar, Nabil Mohie Abdel-Hamid, Mohammed Rizk Abu El-Magd, Aziz Yasri, Hala Mohamed El Hefnawy, Mansour Sobeh   +6 more
doaj   +1 more source

Unveiling Natural and Semisynthetic Acylated Flavonoids: Chemistry and Biological Actions in the Context of Molecular Docking

Molecules, 2022
Acylated flavonoids are widely distributed natural metabolites in medicinal plants and foods with several health attributes. A large diversity of chemical structures of acylated flavonoids with interesting biological effects was reported from several ...
Dina M. El-Kersh, Rania F. Abou El-Ezz, Marwa Fouad, Mohamed A. Farag   +3 more
doaj   +1 more source

Hepatoprotective activity of exogenous RNA [PDF]

The Ukrainian Biochemical Journal, 2015
Hepatoprotective activity of Nuclex, a pharmaceutical composed of low-molecular yeast RNA, was investigated during acute and chronic thioacetamide-induced hepatotoxicity. It is demonstrated, that Nuclex administration at a dose of 200 mg/kg during acute and chronic liver injury produces hepatoprotective effect, which is associated with decrease in ...
I. O. Shmarakov, Т. V. Marchyshak,, V. L. Borschovetska, M. M. Marchenko, Z. Yu. Tkachuk   +4 more
openaire   +3 more sources

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, EarlyView.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source