Results 51 to 60 of about 77,264 (275)

The efficacy of hepatic protectors in patients having chronic hepatitis

Бюллетень сибирской медицины, 2008
The purpose of the present work was the study of new hepatic protectors liproksol influence in the chronic hepatitis viral and alcohol etiology in comparison of carsil effect. 69 patients having chronic hepatitis were include in the investigation.
E. I. Beloborodova, A. I. Vengerovsky, I. K. Livshits, Ye. V. Beloborodova, V. A. Burkovskaya, D. I. Kuzmenko   +5 more
doaj   +1 more source

The protective role of pregnane X receptor in lipopolysaccharide/D-galactosamine-induced acute liver injury. [PDF]

, 2010
The pregnane X receptor (PXR) is a nuclear receptor transcription factor regulating drug-metabolizing enzymes and transporters that facilitate xenobiotic and endobiotic detoxification.
Damjanov, Ivan, Wan, Yu-Jui Yvonne, Wang, Kun   +2 more
core   +2 more sources

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

Advanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang, Hongyi Zhang, Haixiang Guo, Xiwen Zhang, Yidan Wang, Baoyin Wang, Tong Wang, Guokun Zhao, Qing Zhang, Fei Gao, Shuang Liang, Hao Jiang, Yu Ding, Xiliang Du, Jiabao Zhang, Yi Zheng, Xinwei Li, Bao Yuan   +17 more
wiley   +1 more source

Liver‐Targeted Gallium‐Polyphenol Network by Disrupting the ROS/NETs/PANoptosis Axis for Precision Acute Liver Injury Therapy

Advanced Science, EarlyView.
ABSTRACT Acute liver injury (ALI), driven by diverse insults such as drug toxicity and ischemia‐reperfusion, poses a high mortality risk and lacks targeted therapies. While reactive oxygen species (ROS), neutrophil extracellular traps (NETs), and a coordinated cell death pathway PANoptosis have been implicated, their interplay as a unified pathogenic ...
Xiaopeng Cai, Jian He, Jingwen Deng, Ziwei Wang, Zhongshu Wu, Kaiyue Wang, Xiang Zheng, Zhenzhen Gao, Xi Ma, Shumei Wei, Xiangrong Hu, Yuan Ding, Weilin Wang, Min Zhou   +13 more
wiley   +1 more source

Response Surface Methodology Optimization on Ultrasonic‐Assisted Extraction of Chicory (Cichorium intybus L.) and Their UPLC‐ESI‐QTOF‐MS Analysis, Antioxidant and Hepatoprotective Activity

eFood
Chicory (Cichorium intybus L.) roots are commonly roasted and ground to produce a coffee alternative, valued for its robust, nutty taste and absence of caffeine. Historically, it has been utilized to facilitate digestion, serve as a diuretic, and promote
Aizhamal Baiseitova, Ulpan Amzeyeva, Aiya Tolepbergen, Yasmina Ulfanova, Yergazy Shybyray, Lixia Dai, Xiaofei Shang, Abdul Bari Shah, Jeong Yoon Kim, Janar Jenis   +9 more
doaj   +1 more source

Phytolacca dodecandra (Phytolaccaceae) Root Extract Exhibits Antioxidant and Hepatoprotective Activities in Mice with CCl4-Induced Acute Liver Damage

Clinical and Experimental Gastroenterology, 2021
Birhanu Geta Meharie,1 Tewodros Agedew Tunta2 1Department of Pharmacy, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia; 2Department of Pharmacy, College of Medicine and Health Sciences, Arba Minch University, Arba Minch ...
Meharie BG, Tunta TA
doaj  

Ethnomedicine of the Kagera Region, north western Tanzania. Part 3: plants used in traditional medicine in Kikuku village, Muleba District. [PDF]

, 2012
BACKGROUND\ud \ud The Kagera region of north western Tanzania has a rich culture of traditional medicine use and practice. Traditional medicines are the mainstay of healthcare in this region and are known to support the management of many illnesses such ...
Moshi, Mainen J, Otieno, Donald F, Weisheit, Anke   +2 more
core   +2 more sources

Hepatoprotective Constituents from Cleome droserifolia

Chemical and Pharmaceutical Bulletin, 2009
The effect of ethanol extract from aerial parts of Cleome droserifolia was investigated against carbon tetrachloride induced liver injury. The hepatoprotective activity was evaluated through the quantification of biochemical parameters and confirmed using histopathology analysis.
Maged Saad, Abdel-Kader, Saleh Ibrahim, Alqasoumi, Areej Mohammad, Al-Taweel   +2 more
openaire   +3 more sources

Excipient Emulsion–Based Delivery Systems for Enhancing Carotenoid Bioavailability: Advances in Formulation and Gastrointestinal Fate

AgriFood: Journal of Agricultural Products for Food, EarlyView.
Excipient emulsion systems improve carotenoid solubilization, protect against degradation, and enhance gastrointestinal absorption through optimized formulation and digestion behavior. ABSTRACT Carotenoids are bioactive compounds that contribute to human health through antioxidant, provitamin A, and disease‐preventive effects.
Tugce Ceyhan, Elifsu Nemli, Esra Capanoglu, Merve Tomas   +3 more
wiley   +1 more source

Secondary Metabolite Profiling, Anti-Inflammatory and Hepatoprotective Activity of Neptunia triquetra (Vahl) Benth

Molecules, 2021
The present study aimed to analyze the phytoconstituents of Neptunia triquetra (Vahl) Benth. Anti-inflammatory and hepatoprotective activities of ethanol (EE), chloroform (CE) and dichloromethane (DCME) of stem extracts were evaluated using in vivo ...
Nasir Aziz Wagay, Shah Rafiq, Mohammad Aslam Rather, Younas Rasheed Tantray, Feng Lin, Shabir Hussain Wani, Ahmed M. El-Sabrout, Hosam O. Elansary, Eman A. Mahmoud   +8 more
doaj   +1 more source