Results 61 to 70 of about 56,507 (292)

Lactic Acid Bacteria Exert a Hepatoprotective Effect against Ethanol-Induced Liver Injury in HepG2 Cells

Microorganisms, 2021
Alcoholic liver fatty disease (ALFD) is caused by excessive and chronic alcohol consumption. Alcohol consumption causes an imbalance in the intestinal microflora, leading to liver disease induced by the excessive release of endotoxins into the hepatic ...
Ji Yeon Lee, Hyemin Kim, Yulah Jeong, Chang-Ho Kang   +3 more
doaj   +1 more source

Preliminary characterizations, antioxidant and hepatoprotective activity of polysaccharide from Cistanche deserticola

, 2016
To research the preliminary characterizations, antioxidant and hepatoprotective activity of polysaccharides from Cistanche deserticola (CDPs), three polysaccharide fractions, CDP-A, CDP-B and CDP-C, were obtained by successively membrane filtration ...
Guo, Yuanheng, Liu, Boyan, Cao, Lili, Zhao, Qingsheng, Chen, Jinjin, Zhang, Lijun, Zhao, Bing   +6 more
core   +1 more source

Hepatoprotective action of some Ayurvedic drugs: A review [PDF]

, 2023
Yakrut is the Ayurvedic name for liver. It is involved in several physiological processes in the body, including metabolic activities, secretory, retention, purification, and elimination of foreign and endogenous materials. As a result, any impairment or
Ankush Dikondwar, Dikondwar , Ankush, Geeta Vishwanath Sathavane, Sathavane, Geeta Vishwanath, Arun Wankhede, Patil, Shweta, Wankhede, Arun, Shweta Patil   +7 more
core   +1 more source

ROS/pH‐Responsive Phenylboronic Acid–Chitosan Nanoparticles Improve Silymarin‐Mediated Hepatoprotection After Hepatectomy With Gut‐Liver Axis‐Associated Responses

Advanced Science, EarlyView.
Bioactive phenylboronic acid–chitosan nanoparticles enable responsive silymarin delivery for post‐hepatectomy liver protection. The nanoplatform integrates antioxidant and antibacterial functions, improves hepatic recovery, and is associated with coordinated shifts in gut microbiota, metabolites, cytokines, and hepatic proteomic pathways, suggesting a ...
Jinjin Tong, Chaochao Luo, Zezheng Liu, Xinyan Zhang, Daixu Jia, Yang Sun, Zhaonan Zhang, Haoran Shi, Jianfang Wang, Hua Zhang   +9 more
wiley   +1 more source

Antioxidant and hepatoprotective potentials of curcuminoid isolates from turmeric (Curcuma longa) rhizome on CCl4-induced hepatic damage in Wistar rats

Journal of Taibah University for Science, 2020
The present study examined the protective effects of curcuminoid isolates from Curcuma longa against carbon tetrachloride (CCL4)-induced hepatic injury in rats. The hepatoprotective effect of the crude extract (150, 300 and 600 mg/kg bw) and curcuminoids
Jonathan Ibrahim, Adamu Yusuf Kabiru, Tawakaltu Abdulrasheed-Adeleke, Bashir Lawal, Abdulsalam Hassan Adewuyi   +4 more
doaj   +1 more source

AN UPDATED REVIEW ON HEPATOPROTECTIVE MEDICINAL PLANTS [PDF]

, 2012
Medicinal plants may serve as a vital source of potentially useful new compounds for the development of effective therapy to combat a variety of liver problems.
Areefa Shaik, Areefa, Swathi, Swathi, A.Elumalai, A, Eswaraiah, M Chinna   +3 more
core   +1 more source

FBP1‐Mediated Compartmentalization of Glycolytic Enzyme Complexes Suppresses PKM2 Function to Ameliorate MASLD Progression

Advanced Science, EarlyView.
In normal hepatocytes, FBP1 forms compartmentalized complexes with PKM2, ENO1, and LDHA independent of its catalytic activity, inhibiting PKM2 activity and restricting excessive glycolysis. During MASLD progression, FBP1 downregulation markedly reduces the abundance of these complexes and releases the “hijacked” glycolytic enzymes, leading to PKM2 ...
Busong Wang, Yiping Tang, Na Li, Xuening Dai, Jing Wu, Bin Xue, Yuxin Chen, Jingzi Zhang, Lingdong Kong, Chaojun Li, Lei Fang   +10 more
wiley   +1 more source

Advances in hepatoprotective medicinal plants research [PDF]

, 2017
Hepatic dysfunction is a major catastrophe that challenges the health concern researchers. Multiple factors such as biological, chemical and drug overdose are associated with liver disorders.
Muhammad Imran Qadir, Zara Ahmad
core   +1 more source

Models of hepatoprotective activity assessment [PDF]

, 2015
Liver diseases are a major health problem worldwide, making it necessary to develop new molecules that help counteract or prevent such diseases. On account of this fact, investigations aiming to obtain natural and/or synthetic compounds possessing ...
Salazar Aranda, Ricardo, Delgado Montemayor, Cecilia, Cordero Pérez, Paula, Waksman Minsky, Noemí Herminia   +3 more
core   +2 more sources

Stimulation of OGG1 Enhances Oxidative DNA Damage Repair and Protects Against Acute Liver Failure by Acetaminophen

Advanced Science, EarlyView.
Chemical switching of OGG1 by CMM‐98 accelerates oxidative DNA damage repair and enhances hepatocyte resilience during acetaminophen‐induced acute liver injury. By promoting efficient processing of OGG1‐generated repair intermediates, CMM‐98 reduces oxidative damage, preserves cellular integrity, and protects against acute liver failure, identifying ...
Zhenjun Zhao, Rahul Upadhyay, Alice Eddershaw, Chenchen Wang, Yudong Zhao, Olov Wallner, Jinhye Ryu, Nayere Taebnia, Heather Gildie, Emma Scaletti‐Hutchinson, Jonathan R. Davies, Nicole Ziegler, Andreas Krämer, Samantha C. Robinson, Marek Varga, Karolina Singerova, Zuzanna Szaruga, Elisée Wiita, İrşil Güneş, Sheila S. David, Stefan Knapp, Aimo Kannt, Miguel de Vega, Pål Stenmark, Volker M Lauschke, Maurice Michel   +25 more
wiley   +1 more source