Results 61 to 70 of about 112,835 (346)

Silymarin alleviates diclofenac-induced hepatotoxicity in male Wistar rats: Histopathological investigation

Open Veterinary Journal
Background: One of the primary concerns of the pharmaceutical industry is the potential for liver damage caused by drugs. Diclofenac is a member of the family ofnonsteroidall antiinflammatory medications (NSAIDs), which are known for their anti ...
Fawiziah Khalaf Alharbi
doaj   +1 more source

Evaluation of Asparagus officinalis L. extract on hepatotoxicity induced by Senecio Vulgaris L. in Male Rats [PDF]

Journal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Liver disease is one of the global problems that are associated with high mortality. According to the WHO, about 500 million people are living with chronic hepatitis infection, which kills more than one million people a year ...
Fatemeh Moshtaghi, Mohammad Azadbakht, Soheil Azizi, Sobhan Sina, Fateme Alizade   +4 more
doaj  

Hepatoprotective and Antioxidant Potential of Phenolics-Enriched Fraction of Anogeissus acuminata Leaf against Alcohol-Induced Hepatotoxicity in Rats

Medical Sciences, 2022
Anogeissus acuminata is used to treat wounds, diarrhoea, dysentery, and skin ailments. However, its hepatoprotective effect against ethanol-induced liver damage is yet to be reported.
Lal Chand Pal, Shivankar Agrawal, Arti Gautam, Jayhind Kumar Chauhan, Chandana Venkateswara Rao   +4 more
doaj   +1 more source

Hepatoprotective potential of Decalepis hamiltonii (Wight and Arn) against carbon tetrachloride-induced hepatic damage in rats

Journal of Pharmacy and Bioallied Sciences, 2010
Hepatoprotective activity of the roots of Decalepis hamiltonii (Wight and Arn) was studied using carbon tetrachloride (CCl 4 ) induced liver injury model in albino rats.
R Harish, T Shivanandappa
doaj   +1 more source

Antipyretic and hepatoprotective potential of Tinospora crispa and investigation of possible lead compounds through in silico approaches

Food Science & Nutrition, 2019
This research describes an investigation of the antipyretic and hepatoprotective properties of both a crude organic extract and various subfractions of the ethnomedicinal plant Tinospora crispa, using appropriate animal models.
Ahmed Rakib, Shahriar Ahmed, Md. Ashiqul Islam, A. Haye, S. M. Naim Uddin, M. Uddin, M. K. Hossain, A. Paul, T. Emran   +8 more
semanticscholar   +1 more source

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

Chrysophanol, Physcion, Hesperidin and Curcumin Modulate the Gene Expression of Pro-Inflammatory Mediators Induced by LPS in HepG2: In Silico and Molecular Studies

Antioxidants, 2019
Hepatitis is an inflammatory condition that can develop hepatocellular carcinoma. Traditional medicine has always been the pillar of medical practice.
Nabil Mohamed Selim, Abdullah Abdurrahman Elgazar, Nabil Mohie Abdel-Hamid, Mohammed Rizk Abu El-Magd, Aziz Yasri, Hala Mohamed El Hefnawy, Mansour Sobeh   +6 more
doaj   +1 more source

Unveiling Natural and Semisynthetic Acylated Flavonoids: Chemistry and Biological Actions in the Context of Molecular Docking

Molecules, 2022
Acylated flavonoids are widely distributed natural metabolites in medicinal plants and foods with several health attributes. A large diversity of chemical structures of acylated flavonoids with interesting biological effects was reported from several ...
Dina M. El-Kersh, Rania F. Abou El-Ezz, Marwa Fouad, Mohamed A. Farag   +3 more
doaj   +1 more source

Моделювання рецептур сироватково-полуничних напоїв профілактичного призначення [PDF]

, 2017
Expediency of the development of formulae and innovative technologies for production of prophylactic application drinks possessing antioxidant, probiotic and hepatoprotective properties with the use of the secondary dairy product – whey, as well as the ...
Honcharuk, Ya., Nekrasov, P., Tkachenko, N., Vikul, S.   +3 more
core  

Elemene Augments the Effects of Anti‐PD‐1 Immunotherapy on Hepatocellular Carcinoma by Regulating the miR‐130a‐5p/SPP/MHC‐I Axis

Advanced Science, EarlyView.
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang, Mengqing Sun, Heng Dong, Xiaoting Zhang, Jingbo Zhang, Zhengguo Zhang, Mengjie Ni, Lina Li, Yunxin Pei, Xiaoyu Chen, Qian Li, Fangtian Bu, Jiacheng Huang, Liangyu Jiang, Zhuting Fang, Xuliang Chen, Jianxiang Chen, Yiting Qiao, Tian Xie   +18 more
wiley   +1 more source