Results 191 to 200 of about 160,647 (335)

Carrier erythrocyte entrapped thymidine phosphorylase therapy for MNGIE [PDF]

open access: yes, 2008
Bain, MD, Bax, BE, Moran, NF, Muqit, MM
core   +1 more source

Prediction of drug-induced hepatotoxicity using long-term stable primary hepatic 3D spheroid cultures

open access: diamond, 2018
Sabine U. Vorrink   +3 more
openalex   +2 more sources

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

Napabucasin transforms liver microenvironment and boosts immunotherapy efficacy by converting potential metastases into “hot” tumors

open access: yesInterdisciplinary Medicine, EarlyView.
Napabucasin reduces liver metastases by reprogramming the hepatic microenvironment. It induces hepatocyte secretion of CCL21 via c‐Fos activation, recruiting lymphocytes and converting “cold” metastases into immunologically “hot” tumors. This effect is liver‐specific and independent of cancer cells.
Qiongqiong Wang   +19 more
wiley   +1 more source

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