Results 251 to 260 of about 146,077 (348)

Carrier erythrocyte entrapped thymidine phosphorylase therapy for MNGIE [PDF]

, 2008
Bain, MD, Bax, BE, Moran, NF, Muqit, MM
core   +1 more source

Advances in Adjuvant Therapy for Renal Cell Carcinoma: Perspectives on Risk Stratification and Treatment Outcomes

International Journal of Urology, EarlyView.
ABSTRACT Radical surgery is effective for localized renal cell carcinoma (RCC). However, recurrence occurs in up to 40% of patients, underscoring the need for adjuvant therapy to improve the prognosis. Historically, adjuvant treatments, including tyrosine kinase inhibitors, have shown limited success, failing to improve overall survival.
Junya Furukawa, Ryotaro Tomida, Kei Daizumoto, Yutaro Sasaki, Tomoya Fukawa   +4 more
wiley   +1 more source

MDTR: a knowledge-guided interpretable representation for quantifying liver toxicity at transcriptomic level. [PDF]

Front Pharmacol
Sung I, Lee S, Bang D, Yi J, Lee S, Kim S.   +5 more
europepmc   +1 more source

Hepatotoxic Effect of Bile Acids in Inflammatory Bowel Disease

, 1980
M. J. Dew, G. P. van Berge Henegouwen, A. W. M. Huybregts, R N Allan   +3 more
openalex   +1 more source

Labetalol hepatotoxicity

The American Journal of Medicine, 1989
openaire   +2 more sources

Arrhythmogenic Cardiomyopathy: Towards Genotype Based Diagnoses and Management

Journal of Cardiovascular Electrophysiology, EarlyView.
To improve arrhythmogenic cardiomyopathy (ACM) patient care four pillars of ACM research are necessary. The first pillar to improve ACM is cohort studies in which the genotype‐specific natural history of disease is described, and subsequently genotype‐specific risk calculators can be developed, such as the DSP and PLN risk calculators.
Steven A. Muller, Giorgia Bertoli, Jianan Wang, Alessio Gasperetti, Moniek G. P. J. Cox, Hugh Calkins, Anneline S. J. M. te Riele, Daniel P. Judge, Mario Delmar, Richard N. W. Hauer, Gerard J. J. Boink, Marina Cerrone, J. Peter van Tintelen, Cynthia A. James   +13 more
wiley   +1 more source

Insights into medication-induced liver injury: Understanding and management strategies. [PDF]

Toxicol Rep
Tiwari V, Shandily S, Albert J, Mishra V, Dikkatwar M, Singh R, Sah SK, Chand S.   +7 more
europepmc   +1 more source

Darier disease: Current insights and challenges in pathogenesis and management

Journal of the European Academy of Dermatology and Venereology, Volume 39, Issue 5, Page 942-951, May 2025.
Darier disease (DD) is characterized by the following: Disrupted Ca2+ gradients, impaired desmosomes, impaired keratinocyte differentiation, type 17 inflammation, DC and LC ↓, Th17 cells ↑. DD treatment: First line: keratinocyte focused and/or anti‐inflammatory. Second line: experimental approaches like specific targeting of the inflammatory infiltrate.
Monika Ettinger, Susanne Kimeswenger, Isabella Deli, Judith Traxler, Sabine Altrichter, Petar Noack, Jakob D. Wikstrom, Emmanuella Guenova, Wolfram Hoetzenecker   +8 more
wiley   +1 more source

TAK-994 mechanistic investigation into drug-induced liver injury. [PDF]

Toxicol Sci
Shinozawa T, Miyamoto K, Baker KS, Faber SC, Flores R, Uetrecht J, von Hehn C, Yukawa T, Tohyama K, Kadali H, von Grotthuss M, Sudo Y, Smith EN, Diogo D, Zhu AZX, Dragan Y, Cebers G, Wagoner MP.   +17 more
europepmc   +1 more source

Propylthiouracil Hepatotoxicity Mimicking Autoimmune Chronic Active Hepatitis in a Girl

, 1989
Giuseppe Maggiore, Daniela Larizza, Renata Lorini, Costantino De Giacomo, M. S. Scotta, Filiberto Maria Severi   +5 more
openalex   +1 more source