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Anti-tuberculosis drug-induced hepatotoxicity and associated risk factors among patients with pulmonary tuberculosis at a tertiary care hospital in Thailand.

IJID Reg
Mukura S, Ruenwilai P.
europepmc   +1 more source

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Hepatotoxicity From Immune Checkpoint Inhibitors: A Systematic Review and Management Recommendation

Hepatology, 2020
Immune checkpoint inhibitors (ICIs) are monoclonal antibodies targeting immune checkpoint molecules. ICIs are an immunotherapy for the treatment of many advanced malignancies.
T. Peeraphatdit, Jennifer Wang, Matthew A. Odenwald, Shaomin Hu, J. Hart, M. Charlton   +5 more
semanticscholar   +1 more source

Visualization of ONOO- and Viscosity in Drug-Induced Hepatotoxicity with Different Fluorescence Signals by a Sensitive Fluorescent Probe.

Analytical Chemistry, 2020
Drug-induced liver injury (DILI) is considered gradually as a serious public health issue, and hepatotoxicity has been regarded as the main clinical problem caused by it. We suspected that both the intracellular viscosity and peroxynitrite (ONOO-) levels
Yingzhen Deng, Guoqiang Feng
semanticscholar   +1 more source

Hepatotoxicity of Alogliptin [PDF]

Clinical Pharmacokinetics, 2014
In a recent article, Scheen [1] reviews the hepatic safety of incretin-based medications. The author concluded that ‘‘no hepatotoxicity has been reported in the development programme of alogliptin,’’ citing a review article from 2010, the year of alogliptin’s first approval (in Japan) [2].
Elizabeth Barbehenn, Sammy Almashat, Sidney Wolfe, Michael Carome   +3 more
openaire   +2 more sources

Hepatotoxicity of chemotherapy

Expert Opinion on Drug Safety, 2002
The selection of a chemotherapeutic regimen for the oncology patient is based on a thorough assessment of potential hazards relating to the patient's clinical condition and the toxicities of chemotherapy. Liver function abnormalities are commonly seen in this patient population and deducing their aetiology may be difficult.
Nasir Shahab, Bradley A. Sachs, Michael C. Perry, Syed Haider, Rama Balaraman   +4 more
openaire   +2 more sources

Doxycycline and Hepatotoxicity

Acta Clinica Belgica, 1992
The hepatotoxicity of tetracyclines is well known. If microvesicular steatosis due to a high dose of tetracycline has virtually disappeared, it can also be observed with other drugs belonging to the tetracycline family. To our knowledge, hepatotoxicity induced by doxycycline has never been reported.
Liénart, Fabienne, Morissens, Lucien, Jacobs, Paul, Ducobu, Jean   +3 more
openaire   +2 more sources

Botanicals and Hepatotoxicity

Clinical Pharmacology & Therapeutics, 2018
The use of botanicals, often in the form of multi‐ingredient herbal dietary supplements (HDS), has grown tremendously in the past three decades despite their unproven efficacy. This is paralleled by an increase in dietary supplement‐related health complications, notably hepatotoxicity.
Marina Roytman, Victor Navarro, Peter Poerzgen   +2 more
openaire   +3 more sources