Oxidative stress biomarkers in Clarias gariepinus (Burchel, 1822) exposed to Microcystin-LR
Stress levels inflicted by microcystin-LR extracted from Microcystis aeruginosa were assessed by estimating the effects on the oxidative stress biomarkers in the liver, muscle and gill tissues of Clarias gariepinus. Microcystin-LR was administered to the
Patrick Omoregie Isibor
doaj +1 more source
In situ studies on physiological and biochemical responses of four fishes with different trophic levels to toxic cyanobacterial blooms in a large Chinese lake [PDF]
Physiological and biochemical responses of four fishes with different trophic levels to toxic cyanobacterial blooms were studied in a large net cage in Meiliang Bay, a hypereutrophic region of Lake Taihu.
Guo, Longgen +5 more
core +1 more source
Cotargeting TREM2 and IL2 pathways triggers multipronged anticancer immunity
Von Locquenghien et al. report that MiTE‐144, a triggering receptor expressed on myeloid cells 2 (TREM2) blocking antibody fused to interleukin‐2 (IL2) variant with tumour microenvironment restricted activation, demonstrates superior anticancer efficiency in a preclinical setting.
Isaure Vanmeerbeek +2 more
wiley +1 more source
Cytotoxic effects of cylindrospermopsin in mitotic and non-mitotic Vicia faba cells [PDF]
K
Beyer, Dániel +7 more
core +1 more source
Alcohol and periodontal health in adolescence
Alcohol is considered to be a major cause of morbidity and mortality in adults in most parts of the world. Ethanol, the most common hepatotoxin, can injure the liver cells directly or through its toxic metabolites i.e., acetaldehyde and free radicals ...
Ranjan Katyal +2 more
doaj +1 more source
Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein and N-nitrosodimethylamine. [PDF]
BACKGROUND:Clonorchis sinensis is a group I bio-carcinogen responsible for cholangiocarcinoma (CHCA) in humans. However, the mechanism by which C. sinensis promotes carcinogenesis is unclear.
Eun-Min Kim +3 more
doaj +1 more source
Haematology of Clarias gariepinus exposed to Microcystin-LR [PDF]
A static bioassay experiment was conducted by exposing Clarias gariepinus to 200 mg/L and 400m/L of MCLR solutions for 14 days and 28 days to assess the haematological impacts such as estimation of red blood cells, white blood cell and Thrombocytes ...
Isibor, Patrick Omoregie
core +2 more sources
Evolution and detection of cyanobacterial hepatotoxin synthetase genes [PDF]
Mass occurrences (blooms) of cyanobacteria are common in aquatic environments worldwide. These blooms are often toxic, due to the presence of hepatotoxins or neurotoxins. The most common cyanobacterial toxins are hepatotoxins: microcystins and nodularins.
Rantala, Anne
core
Cyclosporine augments hepatic regenerative response in rats [PDF]
A number of mechanisms participate in the hepatic injury that occurs during and following liver transplantation. A normal allograft regenerative response is probably essential for a successful transplant outcome. In this study, the effect of cyclosporine,
Dindzans, V +6 more
core +1 more source
The Model of D-Galactosamine-Induced Injury of Rat Hepatocytes in Primary Culture
D-galactosamine (GalN) is a highly selective hepatotoxin that causes liver damage similar to human viral hepatitis via depletion of uridine nucleotides, which subsequently diminishes synthesis of RNA and proteins. Model of galactosamine hepatotoxicity is
Otto Kučera +5 more
doaj +1 more source

