Results 31 to 40 of about 4,105 (286)

System-level metabolic effects of trematode infections in rodent models [PDF]

, 2010
Background: Trematode infections impose a great burden on the developing world by impairing life quality, productivity and life span of an individual.
Saric, Jasmina
core   +1 more source

Cyanobacterial Hepatotoxin Microcystins

, 2009
Fumio Kondo
openaire   +2 more sources

Valproate (VPA)-Associated Hepatotoxicity

Pediatric Neurology Briefs, 1993
The metabolic pattern of VPA in 170 epileptic patients without symptoms or signs of hepatic side effects was compared to that in 11 patients with early symptoms and signs of hepatotoxicity and in 5 children with fulminant liver failure.
J Gordon Millichap
doaj   +1 more source

Syringic acid demonstrates better anti-apoptotic, anti-inflammatory and antioxidative effects than ascorbic acid via maintenance of the endogenous antioxidants and downregulation of pro-inflammatory and apoptotic markers in DMN-induced hepatotoxicity in rats

Biochemistry and Biophysics Reports, 2023
Dimethyl nitrosamine (DMN) is a known hepatotoxin, carcinogen, and mutagen. This study is therefore carried out to investigate the therapeutic effects of syringic acid (SYRA) and ascorbic acid (ASCA) in DMN-induced hepatic injury in rats.
Olubisi E. Adeyi, Oluwatobi T. Somade, Babajide O. Ajayi, Adewale S. James, Akindele O. Adeyi, Zainab M. Olayemi, Nafisat B. Tella   +6 more
doaj   +1 more source

Purification and Mechanism of Microcystinase MlrC for Catalyzing Linearized Cyanobacterial Hepatotoxins Using Sphingopyxis sp. USTB-05

Toxins, 2022
Cyanobacterial hepatotoxins, including microcystins (MCs) and nodularins (NODs), are widely produced, distributed and extremely hazardous to human beings and the environment.
Qianwen Zou, Junhui Teng, Kunyan Wang, Yiming Huang, Qingbei Hu, Sisi Chen, Qianqian Xu, Haiyang Zhang, Duyuan Fang, Hai Yan   +9 more
doaj   +1 more source

Cyanobacteria Characteristics and Methods for Isolation and Accurate Identification of Cyanotoxins: A Review Article [PDF]

Avicenna Journal of Environmental Health Engineering, 2017
Cyanobacteria are bacteria found in different ecosystems, such as lakes and rocks. These bacteria, capable of photosynthesis, are important sources of oxygen.
Tengku Nadiah Yusof, Mohd Rafatullah, Rohaslinda Mohamad, Norli Ismail, Zarina Zainuddin, Japareng Lalung   +5 more
doaj   +1 more source

Anti-oxidant protective effects of Cassia alata in rats exposed to carbon tetrachloride

Journal of Applied Sciences and Environmental Management, 2006
The protective activity of Cassia alata against carbon tetrachloride (CCl4) – induced hepatotoxicity in rats was assessed. Crude extracts of petals of the plant in 0.5% ethanol were administered by intubation for 14 days prior to injection of 0.5ml Kg-1 ...
MO Wegwu, EO Ayalogu, OJ Sule
doaj   +1 more source

Stereoselective Total Synthesis of the Cyanobacterial Hepatotoxin 7-Epicylindrospermopsin:  Revision of the Stereochemistry of Cylindrospermopsin

, 2016
Stereoselective Total Synthesis of the Cyanobacterial Hepatotoxin 7-Epicylindrospermopsin:  Revision of the Stereochemistry of ...
Grier A. Wallace (2365516), Stephen P. Keen (2029042), Steven M. Weinreb (1651984), Wen-Kui Fang (2985288), Geoffrey R. Heintzelman (2531518)   +4 more
core   +1 more source

Opposing effects of prednisolone treatment on T/NKT cell- and hepatotoxin-mediated hepatitis in mice

, 2014
Prednisolone is a corticosteroid that has been used to treat inflammatory liver diseases such as autoimmune hepatitis and alcoholic hepatitis. However, the results have been controversial, and how prednisolone affects liver disease progression remains ...
H J Kwon, Young Suk Won, B Gao, D Feng, O Park   +4 more
core   +1 more source

The Loss of Nuclear PTEN Increases Tumorigenesis in a Preclinical Mouse Model for Hepatocellular Carcinoma

iScience, 2020
Summary: The PTEN gene is highly mutated in many cancers, including hepatocellular carcinoma. The PTEN protein is located at different subcellular regions—PTEN at the plasma membrane suppresses PI3-kinase signaling in cell growth, whereas PTEN in the ...
Takashi Kato, Tatsuya Yamada, Hideki Nakamura, Atsushi Igarashi, Robert A. Anders, Hiromi Sesaki, Miho Iijima   +6 more
doaj   +1 more source