Results 11 to 20 of about 6,799 (258)
Marine Drugs, 2019 Microcystins are a family of chemically diverse hepatotoxins produced by distantly related cyanobacteria and are potent inhibitors of eukaryotic protein phosphatases 1 and 2A.
Tânia Keiko Shishido +7 more
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Impaired liver regeneration and lipid homeostasis in CCl4 treated WDR13 deficient mice
Laboratory Animal Research, 2020 WDR13 - a WD repeat protein, is abundant in pancreas, liver, ovary and testis. Absence of this protein in mice has been seen to be associated with pancreatic β-cell proliferation, hyperinsulinemia and age dependent mild obesity.
Arun Prakash Mishra +4 more
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Toxins, 2013 Cyanobacteria (also called blue-green algae) are ubiquitous in aquatic environments. Some species produce potent toxins that can sicken or kill people, domestic animals, and wildlife.
Tegwin K. Taylor +4 more
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Proteomic identification of IPSE/alpha-1 as a major hepatotoxin secreted by Schistosoma mansoni eggs. [PDF]
PLoS Neglected Tropical Diseases, 2011 Eggs deposited in the liver of the mammalian host by the blood fluke parasite, Schistosoma mansoni, normally drive a T-helper-2 (Th2)-mediated granulomatous response in immune-competent mice.
Maha-Hamadien Abdulla +3 more
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Analgesic and Hepatoprotective Activity of Methanolic Leaf Extract of Ocimum gratissimum (L.). [PDF]
, 2012 The methanolic extract of Ocimum gratissimum (L.) leaves was screened for analgesic and hepatoprotective activity in albino rats, respectively. The use of the hot-plate method to study central analgesic activity of the leaves extract in albino rats ...
Akubugwo, E. I. +4 more
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Toxins, 2013 A two and a half year old spayed female Miniature Australian Shepherd presented to a Montana veterinary clinic with acute onset of anorexia, vomiting and depression. Two days prior, the dog was exposed to an algal bloom in a community lake. Within h, the
Michael J. Murray +5 more
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Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis. [PDF]
PLoS ONE, 2008 Overexpression of the human c-MYC (MYC) oncogene is one of the most frequently implicated events in the pathogenesis of hepatocellular carcinoma (HCC).
Shelly Beer +5 more
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Marine Drugs, 2019 Microcystins are cyclic heptapeptides from cyanobacteria that are potent inhibitors of protein phosphatases and are toxic to animals and humans. At present, more than 250 microcystin variants are known, with variants reported for all seven peptide ...
Vittoria Mallia +4 more
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Bacteria homologus to Aeromonas capable of microcystin degradation [PDF]
, 2014 Water blooms dominated by cyanobacteria are capable of producing hepatotoxins known as microcystins. These toxins are dangerous to people and to the environment. Therefore, for a better understanding of the biological termination of this increasingly
Dziadek, J. +5 more
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Human Illnesses and Animal Deaths Associated with Freshwater Harmful Algal Blooms—Kansas
Toxins, 2015 Freshwater harmful algal bloom (FHAB) toxins can cause morbidity and mortality in both humans and animals, and the incidence of FHABs in the United States and Kansas has increased. In 2010, the Kansas Department of Health and Environment (KDHE) developed
Ingrid Trevino-Garrison +8 more
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