Results 21 to 30 of about 4,105 (286)

Removal of a potent cyanobacterial hepatotoxin by peat

Journal of Environmental Science and Health, Part A, 2010
Microcystins (cyclic heptapeptides), produced by a number of freshwater cyanobacteria, are of health concern in potable water supplies. In this article, the adsorptive removal of microcystin-RR (MCRR) from the aqueous solution by a low-cost adsorbent, peat, was investigated. The BET surface area of peat was found to be 12.134 m2/g.
Sathishkumar, O., Pavagadhi, S., Mahadevan, A., Balasubramanian, R., Burger, D.F.   +4 more
openaire   +3 more sources

Limitations of acetaminophen as a reference hepatotoxin for the evaluation of in vitro liver models. [PDF]

Toxicol Sci
Acetaminophen is commonly used as a reference hepatotoxin to demonstrate that in vitro human liver platforms can emulate features of clinical drug-induced liver injury.
Livoti LA, Sison-Young R, Reddyhoff D, Fisher CP, Gardner I, Diaz-Nieto R, Goldring CE, Copple IM.   +7 more
europepmc   +2 more sources

Cyanobacterial Hepatotoxin Microcystins: Purification by Affinity Chromatography

, 2005
Fumio Kondo
core   +3 more sources

Redefining IL11 as a regeneration-limiting hepatotoxin and therapeutic target in acetaminophen-induced liver injury [PDF]

, 2021
Acetaminophen (N-acetyl-p-aminophenol; APAP) toxicity is a common cause of liver damage. In the mouse model of APAP-induced liver injury (AILI), interleukin 11 (IL11) is highly up-regulated and administration of recombinant human IL11 (rhIL11) has been ...
Tan, Jessie, Viswanathan, Sivakumar, Schafer, Sebastian, Wang, Mao, Holgate, Robert, Lim, Sze Yun, Widjaja, Anissa A, Yen, Paul M., Widjaja, Anissa A., Ng, Benjamin K, Lim, Wei Wen, Ng, Benjamin, Felkin, Leanne E, Drum, Chester L, Chothani, Sonia P, Shekeran, Shamini G., Felkin, Leanne E., Dong, Jinrui, Cook, Stuart A, Yen, Paul M, Pakkiri, Leroy S, Shekeran, Shamini G, Chothani, Sonia P., Singh, Brijesh K, Adami, Eleonora, Zhou, Jin, Pakkiri, Leroy S., Hearn, Arron, Goh, Joyce, Singh, Brijesh K., Dear, James W, Drum, Chester Lee   +31 more
core   +1 more source

Anti-cyanobacterial activity of Moringa oleifera seeds [PDF]

, 2009
Filtrates from crushed Moringa oleifera seeds were tested for their effects on growth and Photosystem II efficiency of the common bloom-forming cyanobacterium Microcystis aeruginosa. M.
Wendy Beekman, Beekman, W., Miquel Lürling, Lürling, M.F.L.L.W.   +3 more
core   +1 more source

Human Illnesses and Animal Deaths Associated with Freshwater Harmful Algal Blooms—Kansas

Toxins, 2015
Freshwater harmful algal bloom (FHAB) toxins can cause morbidity and mortality in both humans and animals, and the incidence of FHABs in the United States and Kansas has increased. In 2010, the Kansas Department of Health and Environment (KDHE) developed
Ingrid Trevino-Garrison, Jamie DeMent, Farah S. Ahmed, Patricia Haines-Lieber, Thomas Langer, Henri Ménager, Janet Neff, Deon van der Merwe, Edward Carney   +8 more
doaj   +1 more source

Rapid and Highly Sensitive Non-Competitive Immunoassay for Specific Detection of Nodularin

Microorganisms, 2017
Nodularin (NOD) is a cyclic penta-peptide hepatotoxin mainly produced by Nodularia spumigena, reported from the brackish water bodies of various parts of the world.
Sultana Akter, Markus Vehniäinen, Harri T. Kankaanpää, Urpo Lamminmäki   +3 more
doaj   +1 more source

The Biosynthesis of Rare Homo-Amino Acid Containing Variants of Microcystin by a Benthic Cyanobacterium

Marine Drugs, 2019
Microcystins are a family of chemically diverse hepatotoxins produced by distantly related cyanobacteria and are potent inhibitors of eukaryotic protein phosphatases 1 and 2A.
Tânia Keiko Shishido, Jouni Jokela, Anu Humisto, Suvi Suurnäkki, Matti Wahlsten, Danillo O. Alvarenga, Kaarina Sivonen, David P. Fewer   +7 more
doaj   +1 more source

Canine Cyanotoxin Poisonings in the United States (1920s–2012): Review of Suspected and Confirmed Cases from Three Data Sources

Toxins, 2013
Cyanobacteria (also called blue-green algae) are ubiquitous in aquatic environments. Some species produce potent toxins that can sicken or kill people, domestic animals, and wildlife.
Tegwin K. Taylor, Kevin Keel, Jan H. Landsberg, Melissa Miller, Lorraine C. Backer   +4 more
doaj   +1 more source

p53 triggers mitochondrial apoptosis following DNA damage-dependent replication stress by the hepatotoxin methyleugenol

Cell Death and Disease, 2022
Liver cancer is one of the most frequent tumor entities worldwide, which is causally linked to viral infection, fatty liver disease, life-style factors and food-borne carcinogens, particularly aflatoxins.
Max J. Carlsson, Anastasia S. Vollmer, Philipp Demuth, Daniel Heylmann, Diana Reich, Caroline Quarz, Birgit Rasenberger, Teodora Nikolova, Thomas G. Hofmann, Markus Christmann, Julia A. Fuhlbrueck, Simone Stegmüller, Elke Richling, Alexander T. Cartus, Jörg Fahrer   +14 more
doaj   +1 more source