Results 41 to 50 of about 4,105 (286)

Oxidative stress biomarkers in Clarias gariepinus (Burchel, 1822) exposed to Microcystin-LR

open access: yesBeni-Suef University Journal of Basic and Applied Sciences, 2017
Stress levels inflicted by microcystin-LR extracted from Microcystis aeruginosa were assessed by estimating the effects on the oxidative stress biomarkers in the liver, muscle and gill tissues of Clarias gariepinus. Microcystin-LR was administered to the
Patrick Omoregie Isibor
doaj   +1 more source

Increasing Microcystis cell density enhances microcystin synthesis: a mesocosm study [PDF]

open access: yes, 2012
An experimental protocol using mesocosms was established to study the effect of Microcystis sp. cell abundance on microcystin production. The mesocosms (55 L) were set up in a shallow eutrophic lake and received either no (control), low (to simulate a ...
Dietrich, Daniel R   +7 more
core   +1 more source

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito   +8 more
wiley   +1 more source

Impact of Six‐Month Monitoring Compared to Three‐Month Monitoring of Laboratories During Methotrexate Therapy

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate whether extending the American College of Rheumatology–recommended monitoring interval for complete blood count and liver function tests in patients receiving methotrexate (MTX) affects timely detection of medication‐related toxicity.
Spencer Simko   +4 more
wiley   +1 more source

Elevated liver enzymes is not an impediment to allopurinol dose escalation: an observational cohort study

open access: yesArthritis Care &Research, Accepted Article.
Objective Routine liver enzyme monitoring is advocated while on allopurinol but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzymes in gout patients commenced on allopurinol. Methods 150 patients with gout and normal baseline serum aminotransferases initiated on allopurinol were followed ...
May Shuen Tang   +4 more
wiley   +1 more source

Alcohol and periodontal health in adolescence

open access: yesSRM Journal of Research in Dental Sciences, 2012
Alcohol is considered to be a major cause of morbidity and mortality in adults in most parts of the world. Ethanol, the most common hepatotoxin, can injure the liver cells directly or through its toxic metabolites i.e., acetaldehyde and free radicals ...
Ranjan Katyal   +2 more
doaj   +1 more source

Über den Einfluss von Hepatotoxin auf das azetonbildende Vermögen der Leber [PDF]

open access: yes, 1926
Von zahlreichen Autoren ist die Frage wiederholt diskutiert worden, ob Hepatotoxin wirklich eine Funktionsstörung der Leber herbeiführen kann oder nicht, aber die Meinungen darüber sind noch nicht einig.
Oka, M., Kobayashi, M.
core  

Hepatotoxin-induced hypertyrosinemia and its toxicological significance

open access: yes, 2007
A 1H Nuclear Magnetic Resonance (NMR) spectroscopic investigation of the effects of single doses of four model hepatotoxins on male Sprague-Dawley rats showed that hypertyrosinemia was induced by three of the treatments (ethionine 300 mg/kg ...
Clayton, T. Andrew   +7 more
core   +1 more source

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults with Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, Accepted Article.
Objective To characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE). Methods We analyzed cross‐sectional data from 451 adults in the Approaches to Positive, Patient‐centered Experiences of ...
Sarah L. Patterson   +7 more
wiley   +1 more source

Marked inhibition of testosterone biosynthesis by the hepatotoxin nodularin due to apoptosis of Leydig cells.

open access: yes, 2002
We previously observed that the serum testosterone level was greatly reduced in the course of diethylnitrosamine-nodularin-induced hepatocarcinogenesis in Fischer 344 male rats (Lim et al., Gastroenterological Carcinogenesis, 1999).
Sohn, SH, Lim, IK, Song, KY, Park, TJ
core   +1 more source

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