Results 41 to 50 of about 4,163 (290)

Glucagon‐Like Peptide‐1 Receptor Agonists in Multiple Sclerosis: A Topical Narrative Review

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The glucagon‐like peptide‐1 (GLP‐1) receptor agonists (RAs) are a relatively new class of drugs that were initially approved by the US Food and Drug Administration to improve glycemic control in patients with type 2 diabetes mellitus and, subsequently, weight reduction in patients with obesity.
Audrey Y. Chang, Farrah J. Mateen
wiley   +1 more source

Alcohol and periodontal health in adolescence

open access: yesSRM Journal of Research in Dental Sciences, 2012
Alcohol is considered to be a major cause of morbidity and mortality in adults in most parts of the world. Ethanol, the most common hepatotoxin, can injure the liver cells directly or through its toxic metabolites i.e., acetaldehyde and free radicals ...
Ranjan Katyal   +2 more
doaj   +1 more source

Impact of Six‐Month Monitoring Compared to Three‐Month Monitoring of Laboratories During Methotrexate Therapy

open access: yesArthritis Care &Research, EarlyView.
Objective To evaluate whether extending the American College of Rheumatology–recommended monitoring interval for complete blood count and liver function tests in patients receiving methotrexate (MTX) affects timely detection of medication‐related toxicity.
Spencer Simko   +4 more
wiley   +1 more source

Über den Einfluss von Hepatotoxin auf das azetonbildende Vermögen der Leber [PDF]

open access: yes, 1926
Von zahlreichen Autoren ist die Frage wiederholt diskutiert worden, ob Hepatotoxin wirklich eine Funktionsstörung der Leber herbeiführen kann oder nicht, aber die Meinungen darüber sind noch nicht einig.
Oka, M., Kobayashi, M.
core  

Elevated Liver Enzymes Is Not an Impediment to Allopurinol Dose Escalation: An Observational Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Routine liver enzyme monitoring is advocated for while on allopurinol, but supporting guidance is lacking. We assessed the incidence and factors associated with elevated liver enzyme levels in patients with gout commenced on allopurinol. Methods One hundred and fifty patients with gout and normal baseline serum aminotransferases initiated on ...
May Shuen Tang   +4 more
wiley   +1 more source

Connexin 43 plays an important role in the transformation of cholangiocytes with Clonochis sinensis excretory-secretory protein and N-nitrosodimethylamine. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2019
BACKGROUND:Clonorchis sinensis is a group I bio-carcinogen responsible for cholangiocarcinoma (CHCA) in humans. However, the mechanism by which C. sinensis promotes carcinogenesis is unclear.
Eun-Min Kim   +3 more
doaj   +1 more source

Anti-cyanobacterial activity of Moringa oleifera seeds [PDF]

open access: yes, 2009
Filtrates from crushed Moringa oleifera seeds were tested for their effects on growth and Photosystem II efficiency of the common bloom-forming cyanobacterium Microcystis aeruginosa. M.
Wendy Beekman   +3 more
core   +1 more source

Prevalence of Dietary Supplement Use and Potential Medication Interactions Among Adults With Systemic Lupus Erythematosus

open access: yesArthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize the prevalence and correlates of dietary supplement use, identify commonly used supplements, and evaluate potential supplement–medication interactions among adults with systemic lupus erythematosus (SLE).
Sarah L. Patterson   +7 more
wiley   +1 more source

Acetaminophen-cysteine adducts during therapeutic dosing and following overdose

open access: yesBMC Gastroenterology, 2011
Background Acetaminophen-cysteine adducts (APAP-CYS) are a specific biomarker of acetaminophen exposure. APAP-CYS concentrations have been described in the setting of acute overdose, and a concentration >1.1 nmol/ml has been suggested as a marker of ...
Judge Bryan S   +6 more
doaj   +1 more source

Metabolomic analysis indicates a pivotal role of the hepatotoxin microcystin in high light adaptation of Microcystis

open access: yes, 2015
Microcystis is a freshwater cyanobacterium frequently forming nuisance blooms in the summer months. The genus belongs to the predominant producers of the potent hepatotoxin microcystin.
Sven Meissner   +8 more
core   +1 more source

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