Results 101 to 110 of about 7,493 (302)
Comparative Studies on the pH Dependence of DOW of Microcystin-RR and -LR Using LC-MS
The Scientific World Journal, 2011 Microcystins (MCs) are well known worldwide as hepatotoxins produced by cyanobacteria, but little is known about the physicochemical properties of these compounds.
Gaodao Liang +3 more
doaj +1 more source
Nodularia spumigena Peptides—Accumulation and Effect on Aquatic Invertebrates
Toxins, 2015 Thus far, the negative effects of Nodularia spumigena blooms on aquatic organisms have been mainly attributed to the production of the hepatotoxic nodularin (NOD). In the current work, the accumulation of other N.
Hanna Mazur-Marzec +5 more
doaj +1 more source
British Journal of Clinical Pharmacology, EarlyView.With multiple disease‐modifying therapies now available, treatment switching has become an important clinical consideration in the management of spinal muscular atrophy (SMA). While some switches are prompted by suboptimal clinical response, more commonly they are driven by treatment burden, convenience, or adverse events.
Andrej Belančić +4 more
wiley +1 more source
Microcystins in components of twelve New Hampshire lakes of varied trophic status [PDF]
, 1999 Cyanobacteria toxins, called microcystins (MCs), were found in components of twelve, stratified New Hampshire (USA) lakes of varied trophic status during the summer of 1998.
Johnson, Kimberly M.
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis +5 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Aim Elexacaftor/tezacaftor/ivacaftor (ETI) has markedly improved cystic fibrosis (CF) outcomes. However, its long‐term impact on nutrition, metabolism and liver health remains underexplored. We assessed 30‐month changes in pulmonary, nutritional, metabolic and inflammatory markers in people with CF (PwCF) homozygous for F508del.
Nicola Perrotta +5 more
wiley +1 more source
Sensing and Bio-Sensing Research, 2019 Here, we present the development of aptasensor for the label-free, stable, and sensitive detection of environmental toxin microcystin-LR (MC-LR). A thiolated aptamer used as a bio-receptor was covalently immobilized on dual-resonance long-period fiber ...
Saurabh Mani Tripathi +5 more
doaj +1 more source
Palynomorphs of brackish and marine species in cores from the freshwater Lake Sapanca, NW Turkey [PDF]
, 2010 Lake Sapanca, which is located on the Sakarya–Sapanca–İzmit corridor in NW Turkey, is a freshwater lake with numerous fish farms in its catchment. Palynological analyses including non-pollen palynomorphs of a short (38.5 cm) and a longer sediment core ...
Aksu +49 more
core +1 more source
British Journal of Clinical Pharmacology, EarlyView.Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt +13 more
wiley +1 more source