Results 121 to 130 of about 3,207 (257)

Drug-Induced Liver Injury Associated With the Angiotensin II Receptor Blocker Losartan in a 59-Year-Old Woman With Hypertension: A Case Report. [PDF]

Am J Case Rep
Al-Ajaj A, Melki W.
europepmc   +1 more source

A COMPREHENSIVE REVIEW OF HEPATOTOXINS

International Research Journal of Pharmacy, 2019
S Sivakrishnan, M Swamivelmanickam
openaire   +1 more source

Quantification of the Carboxylated LGD‐4033 Long‐Term Metabolite in Human Micro‐Dose Excretion Study Urine Samples

Drug Testing and Analysis, EarlyView.
A validated LC‐HRMS/MS method enabled the first quantitative determination of the LGD‐4033 long‐term metabolite (M5‐b) in urine following controlled micro‐dose administration. The generated urinary reference data support the interpretation of adverse analytical findings and anti‐doping result management. ABSTRACT Selective androgen receptor modulators (
Panagiotis Sakellariou, Sebastian Marcel Schröder, Jasmin Thelen, Linus Korsmeier, Sven Guddat, Christian Görgens, Andreas Thomas, Mario Thevis   +7 more
wiley   +1 more source

Hypertransaminasemia in non-cirrhotic critically-ill patients. [PDF]

World J Hepatol
Fiore M, Cosenza G, Coppolino F, Pota V, Sansone P, Petrou S, Pace MC.   +6 more
europepmc   +1 more source

A translational multimodal machine‐learning prototype predicting valproate response in epilepsy treatment

Epilepsia, EarlyView.
Abstract Objective Epilepsy affects ~1% of the global population and often requires lifelong antiseizure medication (ASM) therapy. Valproic acid (VPA) is a commonly prescribed first‐line ASM, yet only approximately half of patients achieve sustained seizure freedom. Treatment selection remains largely empirical.
Simeon Platte, Afsheen Kumar, Giorgia Guerini, Massimo Pandolfo, Denise Haslinger, Colin B. Josephson, Guillermo Delgado‐García, Navprabhjot Kaur, Michaela‐Pauline Lux, Heiko Stempfle, Chantal Depondt, Reetta Kälviäinen, Felix Rosenow, Sophie von Brauchitsch, Karl Martin Klein, Andreas G. Chiocchetti   +15 more
wiley   +1 more source

Are New Approach Methodologies (NAMs) the Holy Grail of toxicology? [PDF]

Toxicol Sci
Jaeschke H, Ramachandran A.
europepmc   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

Epilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

EPI-DOM framework for assessing fish welfare: external and internal indicators for tilapia. [PDF]

Front Vet Sci
Martínez-Yáñez R.
europepmc   +1 more source

Nutraceutical Benefits of Anchomanes difformis Rhizome and Its Effects on Blood Glucose and Hepatorenal Function in Normoglycemic Rats

Food Chemistry International, EarlyView.
Scientific analysis of Anchomanes difformis roots confirms significant nutraceutical potential, containing high levels of carbohydrates, proteins, and essential minerals. Phytochemical screening revealed antioxidants such as phenols and flavonoids, and although the extracts effectively lowered plasma glucose, safety testing showed dose‐dependent risks.
Lawrence Folorunso Dada, Kingsley Omage, Marshall Arebojie Azeke   +2 more
wiley   +1 more source

Drug-Induced Liver Injury Following Co-ingestion of Veterinary Fenbendazole and Ivermectin for Prostate Cancer: A Case Report. [PDF]

Cureus
Powderly GE, Hassevoort K, Loy M, Balonier J, Sievers C.   +4 more
europepmc   +1 more source