Results 111 to 120 of about 7,493 (302)

Drug-induced liver injury. Part I: Classification, diagnosis and treatment

open access: yesClinical & Experimental Hepatology
Drug-induced liver injury (DILI) is a growing clinical problem. Antibiotics remain the most common cause of DILI in Europe. Their clinical spectrum is very broad, from asymptomatic to acute liver failure. Currently, DILI is categorized as hepatocellular (
Dorota M. Kozielewicz   +2 more
doaj   +1 more source

HLA genotype testing for carbamazepine, oxcarbazepine and eslicarbazepine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Carbamazepine is licensed in the United Kingdom for the treatment of epilepsy, bipolar disorder and trigeminal neuralgia. The related compounds oxcarbazepine and eslicarbazepine are licensed for the treatment of epilepsy. These drugs can cause immune‐mediated hypersensitivity reactions, which typically affect the skin, and can be of variable severity ...
Lucy Galloway   +24 more
wiley   +1 more source

CYANO RT-Microarray: A Novel Tool to Detect Gene Expression in Cyanobacteria [PDF]

open access: yes, 2018
EU μAQUA made early warning systems for freshwater pathogens and toxins. Barcodes for each cyanobacterial toxin gene published before 2011 were designed and used in a microarray format to capture messenger RNA to detect toxin gene expression at early ...
Medlin, LK
core  

Patients on statins with elevated transaminases: Frequency of follow‐up creatine kinase testing and gastroenterology referral

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Purpose To quantify how often creatine kinase (CK) is measured after newly elevated aminotransferases in statin users, and whether absent CK data are associated with gastroenterology (GI) referrals. Methods Retrospective chart review of adult outpatients on statins with a first alanine/aspartate aminotransferase (ALT/AST) elevation during a 5 ...
Faris Shweikeh   +5 more
wiley   +1 more source

A prospective series of acute rivaroxaban overdose, coagulopathy and bleeding complications (ATOM 11)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim There is limited research describing rivaroxaban overdose. We aim to describe rivaroxaban overdose, coagulopathy and bleeding complications. Methods This is a prospective series of acute adult (>14 years) rivaroxaban overdose presentations >40 mg enrolled in the Australian Toxicology Monitoring study and presenting to three Australian clinical ...
Katherine Z. Isoardi   +3 more
wiley   +1 more source

Inherited metabolic epilepsies–established diseases, new approaches

open access: yesEpilepsia Open, EarlyView.
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley   +1 more source

Diversity and seasonality of cyanotoxins in Lake Garda (Italy): potential for hepatotoxic microcystins transfer through the food web [PDF]

open access: yes, 2012
42012 SHA 1openToxic cyanobacteria occurrence is a global concern in many eutrophic freshwater ecosystems due to their production of highly toxic secondary metabolites (cyanotoxins): hepatotoxins (microcystins, nodularins), neurotoxins (saxitoxins ...

core  

Nutritional Potential, Phytochemical Content, In Vivo Antioxidant, and Antanemic Potential of Musa paradisiaca Flower

open access: yesFood Chemistry International, EarlyView.
After collecting Musa paradisiaca leaves, some were dried and others were used to produce aqueous extracts. The extracts and powders were characterized and then administered to rats made anaemic by PHZ. After 14 days of administration of the two samples, the rats were euthanized and it was observed that after 9 days of treatment, the aqueous extract ...
Josée Rebeca Nombo   +8 more
wiley   +1 more source

Previsão da capacidade de remoção de cianobactérias e cianotoxinas na ETA de Alcantarilha [PDF]

open access: yes, 2012
Os blooms de cianobactérias em reservatórios de água destinada à produção de água para consumo humano originam muitos problemas, sendo o mais preocupante o facto de uma proporção significativa de cianobactérias produzirem uma ou mais toxinas.
Campinas, Margarida Páscoa   +3 more
core  

Clinical Images: A thorn injury, a sea‐borne culprit, and a tenosynovitis dilemma

open access: yes
Arthritis &Rheumatology, EarlyView.
Jacopo Ciaffi   +8 more
wiley   +1 more source

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