Results 131 to 140 of about 4,021 (283)

Occurrence of Microcystis aeruginosa and microcystins in Río de la Plata river (Argentina)

Acta Toxicológica Argentina, 2007
This paper is the first report on microcystins producer blooms of Microcystis aeruginosa in the Argentinean coast of the Río de la Plata river, the most important drinking water supply of Argentina. The distribution of toxic cyanobacterium Microcystis cf.
Darío Andrinolo, Paulo Pereira, Leda Giannuzzi, Claudia Aura, Silvia Massera, Mariela Caneo, Josep Caixach, Mónica Barco, Ricardo Echenique   +8 more
doaj  

Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage

Journal of Applied Toxicology, EarlyView.
ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal, Abdullah Burak Karaduman, Büşra Korkut Çelikateş, Merve Güven, Özlem Atlı‐Eklioğlu, Sinem Ilgın   +5 more
wiley   +1 more source

Protective Role of Polydatin Against Vancomycin‐Induced Lung Toxicity via Oxidative Stress, Inflammation, Endoplasmic Reticulum Stress, Apoptosis, and Ferroptosis Pathways

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study aimed to evaluate whether polydatin (Poly) could eliminate the harmful effects of vancomycin (VCM) on the lungs of rats. Rats were administered VCM (200 mg/kg) and Poly (50 mg/kg), both separately and in combination, for a duration of 7 days.
Serpil Aygörmez, Sefa Küçükler, Selim Çomaklı, Hasan Şimşek, Özge Kandemir, Fatih Mehmet Kandemir, Şaban Maraşlı   +6 more
wiley   +1 more source

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol, Alparslan Kadir Devrim, Miyase Çinar, Mahmut Sözmen, Fatma Betül Akça   +4 more
wiley   +1 more source

The Expanding Role of Companion Diagnostics in Infectious Diseases: Lessons From Abacavir and Human Immunodeficiency Virus Care

iLABMED, EarlyView.
Yi‐Wei Tang, Eric von Hofe
wiley   +1 more source

Development of an Efficient and Scalable Process for Preparing Timolol N‐Nitrosamine Impurities B, C, E, H, I, J, and Their ADMET Evaluation

Journal of Heterocyclic Chemistry, EarlyView.
N‐nitrosamine impurities (B, C, E, H, I, J) of timolol maleate are easily synthesized from diethyl malonate and 3,4‐dichloro‐1,2,5‐thiadiazole. Good yields and precise impurity profiling are made possible by the effective technique, which also ensures pharmaceutical safety and strengthens regulatory compliance.
Kottolla Sai Prasad, Chithaluri Sudhakar, Vijaya Krishna Ravi, Bijaya Kethan Sahoo   +3 more
wiley   +1 more source

Delayed-Onset Hepatocellular Liver Injury Associated With Nitrofurantoin and Herbal Supplement Use: A Case Report With Multiple Potential Exposures. [PDF]

Case Rep Gastrointest Med
Mendoza E, Pustake M, Annabi J, Torres J, Mendez J, Kattamuri L, Williams B, Deoker A.   +7 more
europepmc   +1 more source

Response of mouse liver coumarin 7-hydroxylase activity to hepatotoxins: Dependence on strain and agent and comparison to other monooxygenases

, 1993
Acute effects of a single intraperitoneal dose of allyl alcohol (AA, 64 mg/kg), dimethylnitrosamine (DMNA, 30 mg/kg), hexachlorobutadiene (HCBD, 50 mg/kg), carbon tetrachloride (CCl4, 24 mg/kg), cocaine (60 mg/kg) and pyrazole (300 mg/kg) on the hepatic ...
Pellinen, P., Pasanen, M., Lang, M., Rautio, A., Stenback, F., Pelkonen, O.   +5 more
core  

Integrating Biomarker‐Based Fatty Liver Indices Into Multidisciplinary Treatment Pathways for Digestive Tumors

iLABMED, EarlyView.
Xudong Song, Jingjing Dai, Guoquan Tao
wiley   +1 more source

Impact of cystic fibrosis transmembrane conductance regulator modulator therapies on liver stiffness and liver enzymes: An observational perspective single‐center cohort study

JPGN Reports, EarlyView.
Abstract Objectives The efficacy of cystic fibrosis transmembrane conductance regulator (CFTR)‐modulator therapies in preventing or ameliorating cystic fibrosis liver disease (CFLD) by correcting CFTR in cholangiocytes is not well‐documented. This study aimed to assess liver function during CFTR‐modulators.
Laura Giugliano, Elisabetta Augustoni, Antonio Pizzol, Anna Opramolla, Cristina Chiadò, Anna Zagaria, Irene Esposito, Giulia Roberto, Alice Ponte, Andrea Evangelista, Paola Quarello, Michele Pinon, Pier Luigi Calvo   +12 more
wiley   +1 more source