Results 11 to 20 of about 4,323 (190)

Degradation of cyanobacterial hepatotoxins in batch experiments

open access: yesWater Science and Technology, 2001
Bank filtration offers a cost effective and low maintenance technique for the removal of cyanobacterial hepatotoxins from drinking water. For bank filtration to be effective, the toxins must be degraded. The broad aim of this research was to determine whether the hepatotoxins, nodularin and microcystin-LR, could be completely removed from the soil ...
M J, Miller, H J, Fallowfield
openaire   +3 more sources

Unique Properties of Hepatocarcinogenesis-Resistant DRH Rat Hepatocytes Linked or Not Linked to the Drh1 Locus on Rat Chromosome 1 [PDF]

open access: yesInternational Journal of Hepatology, 2011
Hepatocarcinogenesis-resistant DRH rats exhibit few and small preneoplastic hepatocytic lesions during hepatocarcinogenesis, of which traits have been assigned to two major chromosomal regions, Drh1 and Drh2. In this study, hepatocytes from DRH.F344-Drh1,
Norikazu Hashimoto   +4 more
doaj   +3 more sources

Development of a convenient in vivo hepatotoxin assay using a transgenic zebrafish line with liver-specific DsRed expression.

open access: yesPLoS ONE, 2014
Previously we have developed a transgenic zebrafish line (LiPan) with liver-specific red fluorescent protein (DsRed) expression under the fabp10a promoter. Since red fluorescence in the liver greatly facilitates the observation of liver in live LiPan fry,
Xiaoyan Zhang, Caixia Li, Zhiyuan Gong
doaj   +2 more sources

Stability of cyanotoxins, microcystin-LR, microcystin-RR and nodularin in seawater and BG-11 medium of different salinity [PDF]

open access: yesOceanologia, 2001
Microcystins and nodularin are potent hepatotoxins produced by fresh and seawater cyanobacteria. The persistence of three hepatotoxins - microcystin-LR, microcystin-RR and nodularin - was investigated in sterile BG-11 medium of different salinity and in ...
Hanna Mazur, Marcin Pliñski
doaj   +1 more source

Occurrence of the Microcystins MC-LW and MC-LF in Dutch Surface Waters and Their Contribution to Total Microcystin Toxicity

open access: yesMarine Drugs, 2013
Microcystins (MCs) are the most frequently found cyanobacterial toxins in freshwater systems. Many MC variants have been identified and variants differ in their toxicity. Recent studies showed that the variants MC-LW and MC-LF might be more toxic than MC-
Elisabeth J. Faassen, Miquel Lürling
doaj   +1 more source

Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis. [PDF]

open access: yesPLoS ONE, 2008
Overexpression of the human c-MYC (MYC) oncogene is one of the most frequently implicated events in the pathogenesis of hepatocellular carcinoma (HCC).
Shelly Beer   +5 more
doaj   +1 more source

Development, Validation and Application of a Targeted LC-MS Method for Quantification of Microcystins and Nodularin: Towards a Better Characterization of Drinking Water [PDF]

open access: yes, 2022
peer reviewedCyanotoxins can be produced in surface waters by cyanobacterial blooms, mostly during summer and early autumn. Intoxications would result from consumption of water contaminated with the potent hepatotoxins, microcystins and nodularin ...
Bart Huybrechts   +14 more
core   +1 more source

Plant and Fungal Hepatotoxicities of Cattle in Australia, with a Focus on Minimally Understood Toxins

open access: yesToxins, 2020
Plant- and fungus-derived hepatotoxins are a major cause of disease and production losses in ruminants in Australia and around the world. Many are well studied and described in the literature; however, this is not the case for a number of ...
Eve M. Manthorpe   +3 more
doaj   +1 more source

1,1-Dichloroethylene: An Apoptotic Hepatotoxin? [PDF]

open access: yesEnvironmental Health Perspectives, 1984
Within 2 hr after 1,1-dichloroethylene administration, the following phenomena occur in livers of fasted rats: dilation and disruption of bile canaliculi, plasma membrane invagination and loss of microvilli, cytoplasmic vacuolation, and loss of density in mitochondrial matrices.
E S, Reynolds   +3 more
openaire   +3 more sources

Effect of hepato-toxins in the acceleration of hepatic fibrosis in hepatitis B mice.

open access: yesPLoS ONE, 2020
Chronic liver diseases such as hepatitis B viral (HBV) infection and liver fibrosis have been a major health problem worldwide. However, less research has been conducted owing to the lack of animal models.
Suchithra Poilil Surendran   +6 more
doaj   +1 more source

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