Results 11 to 20 of about 3,207 (257)
Toxins, 2020 Plant- and fungus-derived hepatotoxins are a major cause of disease and production losses in ruminants in Australia and around the world. Many are well studied and described in the literature; however, this is not the case for a number of ...
Eve M. Manthorpe +3 more
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1,1-Dichloroethylene: An Apoptotic Hepatotoxin? [PDF]
Environmental Health Perspectives, 1984 Within 2 hr after 1,1-dichloroethylene administration, the following phenomena occur in livers of fasted rats: dilation and disruption of bile canaliculi, plasma membrane invagination and loss of microvilli, cytoplasmic vacuolation, and loss of density in mitochondrial matrices.
E S, Reynolds +3 more
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Cells, 2023 We wished to understand the metabolic reprogramming underlying liver fibrosis progression in mice. Administration to male C57BL/6J mice of the hepatotoxins carbon tetrachloride (CCl4), thioacetamide (TAA), or a 60% high-fat diet, choline-deficient, amino-
Diren Beyoğlu +5 more
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PLoS ONE, 2014 Previously we have developed a transgenic zebrafish line (LiPan) with liver-specific red fluorescent protein (DsRed) expression under the fabp10a promoter. Since red fluorescence in the liver greatly facilitates the observation of liver in live LiPan fry,
Xiaoyan Zhang, Caixia Li, Zhiyuan Gong
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Effect of hepato-toxins in the acceleration of hepatic fibrosis in hepatitis B mice.
PLoS ONE, 2020 Chronic liver diseases such as hepatitis B viral (HBV) infection and liver fibrosis have been a major health problem worldwide. However, less research has been conducted owing to the lack of animal models.
Suchithra Poilil Surendran +6 more
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Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity. [PDF]
PLoS ONE, 2012 Hepatotoxicity is associated with major changes in liver gene expression induced by xenobiotic exposure. Understanding the underlying mechanisms is critical for its clinical diagnosis and treatment.
María N Lardizábal +5 more
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Toxins, 2022 Exposure to cyanobacterial hepatotoxins has been linked to the promotion and increased incidence of liver cancer in pre-clinical and epidemiologic studies.
Igor Mrdjen +3 more
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International Journal of Hepatology, 2011 Hepatocarcinogenesis-resistant DRH rats exhibit few and small preneoplastic hepatocytic lesions during hepatocarcinogenesis, of which traits have been assigned to two major chromosomal regions, Drh1 and Drh2. In this study, hepatocytes from DRH.F344-Drh1,
Norikazu Hashimoto +4 more
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Bacteria homologus to Aeromonas capable of microcystin degradation
Open Life Sciences, 2015 Water blooms dominated by cyanobacteria are capable of producing hepatotoxins known as microcystins. These toxins are dangerous to people and to the environment.
Mankiewicz-Boczek J. +5 more
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Experimental models used for the study of antihepatotoxic agents
Journal of Acute Disease, 2012 Both in vitro and in vivo liver models have been developed in the past years to study the hepatoprotective agents. These systems measure the ability of the test drug to prevent or cure liver toxicity (induced by various hepatotoxins) in experimental ...
Feroz Ahmad, Nahida Tabassum
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