Results 21 to 30 of about 4,021 (283)
Sedimentation Patterns of Toxin-Producing Microcystis Morphospecies in Freshwater Reservoirs
Toxins, 2013 Understanding the annual cycle of Microcystis is essential for managing the blooms of this toxic cyanobacterium. The current work investigated the sedimentation of microcystin-producing Microcystis spp.
Antonio Quesada +3 more
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Marine Drugs, 2013 Microcystins (MCs) are the most frequently found cyanobacterial toxins in freshwater systems. Many MC variants have been identified and variants differ in their toxicity. Recent studies showed that the variants MC-LW and MC-LF might be more toxic than MC-
Elisabeth J. Faassen, Miquel Lürling
doaj +1 more source
Hepatotoxin-induced changes in the adult murine liver promote MYC-induced tumorigenesis. [PDF]
PLoS ONE, 2008 Overexpression of the human c-MYC (MYC) oncogene is one of the most frequently implicated events in the pathogenesis of hepatocellular carcinoma (HCC).
Shelly Beer +5 more
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Toxins, 2020 Plant- and fungus-derived hepatotoxins are a major cause of disease and production losses in ruminants in Australia and around the world. Many are well studied and described in the literature; however, this is not the case for a number of ...
Eve M. Manthorpe +3 more
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1,1-Dichloroethylene: An Apoptotic Hepatotoxin? [PDF]
Environmental Health Perspectives, 1984 Within 2 hr after 1,1-dichloroethylene administration, the following phenomena occur in livers of fasted rats: dilation and disruption of bile canaliculi, plasma membrane invagination and loss of microvilli, cytoplasmic vacuolation, and loss of density in mitochondrial matrices.
E S, Reynolds +3 more
openaire +3 more sources
Cells, 2023 We wished to understand the metabolic reprogramming underlying liver fibrosis progression in mice. Administration to male C57BL/6J mice of the hepatotoxins carbon tetrachloride (CCl4), thioacetamide (TAA), or a 60% high-fat diet, choline-deficient, amino-
Diren Beyoğlu +5 more
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Effect of hepato-toxins in the acceleration of hepatic fibrosis in hepatitis B mice.
PLoS ONE, 2020 Chronic liver diseases such as hepatitis B viral (HBV) infection and liver fibrosis have been a major health problem worldwide. However, less research has been conducted owing to the lack of animal models.
Suchithra Poilil Surendran +6 more
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Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity. [PDF]
PLoS ONE, 2012 Hepatotoxicity is associated with major changes in liver gene expression induced by xenobiotic exposure. Understanding the underlying mechanisms is critical for its clinical diagnosis and treatment.
María N Lardizábal +5 more
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Toxins, 2022 Exposure to cyanobacterial hepatotoxins has been linked to the promotion and increased incidence of liver cancer in pre-clinical and epidemiologic studies.
Igor Mrdjen +3 more
doaj +1 more source
International Journal of Hepatology, 2011 Hepatocarcinogenesis-resistant DRH rats exhibit few and small preneoplastic hepatocytic lesions during hepatocarcinogenesis, of which traits have been assigned to two major chromosomal regions, Drh1 and Drh2. In this study, hepatocytes from DRH.F344-Drh1,
Norikazu Hashimoto +4 more
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