Results 21 to 30 of about 4,323 (190)
We wished to understand the metabolic reprogramming underlying liver fibrosis progression in mice. Administration to male C57BL/6J mice of the hepatotoxins carbon tetrachloride (CCl4), thioacetamide (TAA), or a 60% high-fat diet, choline-deficient, amino-
Diren Beyoğlu +5 more
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Biostatistical Analysis on Synergetic therapy of the three plants
The liver is an important metabolic organ consisting of four different sized lobes in our bodies. Theimportant function of liver includes the elimination of toxic material, detoxication and regulationof theblood, blood clotting, and manufacture of vital ...
Dr. Bin Zhao
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Reference genes for real-time PCR quantification of microRNAs and messenger RNAs in rat models of hepatotoxicity. [PDF]
Hepatotoxicity is associated with major changes in liver gene expression induced by xenobiotic exposure. Understanding the underlying mechanisms is critical for its clinical diagnosis and treatment.
María N Lardizábal +5 more
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Exposure to cyanobacterial hepatotoxins has been linked to the promotion and increased incidence of liver cancer in pre-clinical and epidemiologic studies.
Igor Mrdjen +3 more
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Proteomic responses of HepG2 cell monolayers and 3D spheroids to selected hepatotoxins [PDF]
Despite the importance of hepatotoxicity testing in the development of new potential pharmaceuticals, standardized methods for preclinical in vitro hepatotoxicity is complicated by the perceived adequacy of approach, diversity of origin of cells, and the
Hurrell, Tracey +2 more
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Transcription regulation of hepatotoxins microcystin and nodularin from cyanobacteria [PDF]
The role and function of hepatotoxins microcystin and nodularin produced by M.aeruginosa PCC 7806 and N. spumigena NSORlO respectively have yet to be elucidated.
Root, Hannah Patricia
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Bacteria homologus to Aeromonas capable of microcystin degradation
Water blooms dominated by cyanobacteria are capable of producing hepatotoxins known as microcystins. These toxins are dangerous to people and to the environment.
Mankiewicz-Boczek J. +5 more
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Chemical Study of the Hepatotoxins from Microcystis Aeruginosa Collected in California
Four cyclic peptide toxins were purified and quantified from the aqueous extract of algal cell material utilizing high performance liquid chromatography, thin layer chromatography, and fast atom bombardment mass spectrometry.
F. D. Galey +5 more
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Aim: The aim of this study was to conduct a rapid and comprehensive analysis of the reservoir using physical, chemical and biological variables comprising water and sediment as also to verify if a one-sampling campaign can produce information that is ...
Frederico Guilherme de Souza Beghelli +5 more
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Experimental models used for the study of antihepatotoxic agents
Both in vitro and in vivo liver models have been developed in the past years to study the hepatoprotective agents. These systems measure the ability of the test drug to prevent or cure liver toxicity (induced by various hepatotoxins) in experimental ...
Feroz Ahmad, Nahida Tabassum
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